Acetazolamide may prevent some patients with chronic obstructive pulmonary disease (COPD) from suffering altitude-related adverse health effects (ARAHE) when traveling, a randomized controlled trial showed.
In patients with moderate to severe COPD traveling to and staying for 2 days at 3,100 m, ARAHE occurred in 50% of those taking acetazolamide compared with 74% of those taking placebo (HR 0.60, 95% CI 0.40-0.89, P
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