* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Tuesday, September 30, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    The Police Made Chart History With This 1979 Hit Nearly 50 Years Ago – Yahoo

    How The Police Changed Music Forever with Their Iconic 1979 Hit Nearly 50 Years Ago

    Good Deed Entertainment Acquires Worldwide Rights To Liza Mandelup’s Documentary ‘Caterpillar’ – Deadline

    Good Deed Entertainment Lands Global Rights to Liza Mandelup’s Captivating Documentary ‘Caterpillar

    Danielle Fishel Explains Why Being on “DWTS” Makes Her Feel ‘Like It’s 1994 Again’ Filming “Boy Meets World” (Exclusive) – Yahoo

    Danielle Fishel Explains Why Being on “DWTS” Makes Her Feel ‘Like It’s 1994 Again’ Filming “Boy Meets World” (Exclusive) – Yahoo

    Jussie Smollett Claims He Was ‘Disrespected’ on the ‘Special Forces’ Season Premiere – Yahoo

    Jussie Smollett Opens Up About Feeling ‘Disrespected’ During the ‘Special Forces’ Season Premiere

    TicketSmarter Fall Entertainment Guide – Eastern Illinois University Athletics

    TicketSmarter Fall Entertainment Guide – Eastern Illinois University Athletics

    Cardi B Adds More Dates to Little Miss Drama Tour: ‘Y’all Making Me Work’ – Yahoo

    Cardi B Extends Little Miss Drama Tour: “Y’all Making Me Work

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Saving Energy and Money with Smart Technology – Terms of Service with Clare Duffy – Podcast on CNN Podcasts – CNN

    Saving Energy and Money with Smart Technology – Terms of Service with Clare Duffy – Podcast on CNN Podcasts – CNN

    Four Strategic Signals Technology Leaders Are Tuning In To – SPONSOR CONTENT FROM ARM – Harvard Business Review

    Four Essential Strategic Signals Every Technology Leader Should Watch

    Virginia Tech hosts annual New Music + Technology Festival this week – Cardinal News

    Virginia Tech Kicks Off Exciting Annual New Music and Technology Festival This Week

    Why I gave the world wide web away for free | Tim Berners-Lee – The Guardian

    Why I Decided to Make the World Wide Web Free for Everyone | Tim Berners-Lee

    From shale to steam: Fossil fuel technology boosts clean geothermal energy – Washington Examiner

    From Shale to Steam: How Fossil Fuel Technology is Powering a Clean Geothermal Energy Revolution

    How Sustainable Technology is Shaping a Greener Future – Technology Magazine

    How Sustainable Technology is Driving the Revolution Toward a Greener Future

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    The Police Made Chart History With This 1979 Hit Nearly 50 Years Ago – Yahoo

    How The Police Changed Music Forever with Their Iconic 1979 Hit Nearly 50 Years Ago

    Good Deed Entertainment Acquires Worldwide Rights To Liza Mandelup’s Documentary ‘Caterpillar’ – Deadline

    Good Deed Entertainment Lands Global Rights to Liza Mandelup’s Captivating Documentary ‘Caterpillar

    Danielle Fishel Explains Why Being on “DWTS” Makes Her Feel ‘Like It’s 1994 Again’ Filming “Boy Meets World” (Exclusive) – Yahoo

    Danielle Fishel Explains Why Being on “DWTS” Makes Her Feel ‘Like It’s 1994 Again’ Filming “Boy Meets World” (Exclusive) – Yahoo

    Jussie Smollett Claims He Was ‘Disrespected’ on the ‘Special Forces’ Season Premiere – Yahoo

    Jussie Smollett Opens Up About Feeling ‘Disrespected’ During the ‘Special Forces’ Season Premiere

    TicketSmarter Fall Entertainment Guide – Eastern Illinois University Athletics

    TicketSmarter Fall Entertainment Guide – Eastern Illinois University Athletics

    Cardi B Adds More Dates to Little Miss Drama Tour: ‘Y’all Making Me Work’ – Yahoo

    Cardi B Extends Little Miss Drama Tour: “Y’all Making Me Work

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Saving Energy and Money with Smart Technology – Terms of Service with Clare Duffy – Podcast on CNN Podcasts – CNN

    Saving Energy and Money with Smart Technology – Terms of Service with Clare Duffy – Podcast on CNN Podcasts – CNN

    Four Strategic Signals Technology Leaders Are Tuning In To – SPONSOR CONTENT FROM ARM – Harvard Business Review

    Four Essential Strategic Signals Every Technology Leader Should Watch

    Virginia Tech hosts annual New Music + Technology Festival this week – Cardinal News

    Virginia Tech Kicks Off Exciting Annual New Music and Technology Festival This Week

    Why I gave the world wide web away for free | Tim Berners-Lee – The Guardian

    Why I Decided to Make the World Wide Web Free for Everyone | Tim Berners-Lee

    From shale to steam: Fossil fuel technology boosts clean geothermal energy – Washington Examiner

    From Shale to Steam: How Fossil Fuel Technology is Powering a Clean Geothermal Energy Revolution

    How Sustainable Technology is Shaping a Greener Future – Technology Magazine

    How Sustainable Technology is Driving the Revolution Toward a Greener Future

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home General

After Cervical Artery Dissection, Early Anticoagulant Might Be Better

February 11, 2024
in General
After Cervical Artery Dissection, Early Anticoagulant Might Be Better
Share on FacebookShare on Twitter

PHOENIX — Anticoagulation worked at least as well as antiplatelet medication for stroke prevention after cervical artery dissection, an observational study suggested.

Subsequent ischemic stroke was numerically but not significantly less common with anticoagulation than with antiplatelet use in this population both at 30 days (adjusted HR 0.71, 95% CI 0.45-1.12) and 180 days (adjusted HR 0.80, 95% CI 0.28-2.24), according to Shadi Yaghi, MD, of Brown Medical School in Providence, Rhode Island.

For patients with occlusive dissection, the advantage of anticoagulation was significant (aHR 0.40, 95% CI 0.18-0.88, P=0.009 for interaction), Yaghi reported at the American Stroke Association International Stroke Conference. The STOP-CAD study findings also were published in Stroke.

Anticoagulation didn’t carry higher risk of major hemorrhage in the first 30 days (aHR 1.39, 95% CI 0.35-5.45, P=0.637), but that risk became substantial by 180 days (aHR 5.56, 95% CI 1.53-20.13, P=0.009).

“Our study does not rule out a benefit of anticoagulation in reducing ischemic stroke risk, particularly in patients with occlusive dissection,” the researchers concluded. “If anticoagulation is chosen, it seems reasonable to switch to antiplatelet therapy before 180 days to lower the risk of major bleeding.”

Late-breaking science session moderator Lauren Sansing, MD, of Yale School of Medicine in New Haven, Connecticut, agreed with those conclusions.

“What it looks like is that probably early anticoagulation will be better, but that after 30 days we should be switching, probably not keeping those patients on anticoagulation,” she told MedPage Today.

Cervical artery dissection accounts for only about 2% of ischemic strokes but up to 25% of those in young adults ages 50 and younger. Some 3% result in subsequent stroke, so guidelines have recommended antithrombotic therapy for 3 to 6 months afterward without specifying anticoagulation or antiplatelet use.

With relatively small numbers of events and a low overall risk of stroke on either of those medications is low, “it’s hard to then show that one treatment is beneficial over the other,” Sansing noted. “But it’s incredibly important because, again, these are young people, so another stroke is a devastating event.”

Practice has been in equipoise with clinicians relying on intuition about what might be better for any given patient, she added.

Two prior trials, CADISS and TREAT-CAD, compared vitamin K antagonist anticoagulation against antiplatelet therapy after cervical artery dissection but didn’t definitively answer the question. One suggested anticoagulation was superior but was underpowered; the other failed to show non-inferiority of aspirin.

With its 4,023 patients, STOP-CAD “dwarfs any kind of studies that were done before, so that’s the big strength. And it’s a well done study for a retrospective study,” noted session co-moderator Tudor G. Jovin, MD, of the Cooper Neurological Institute in Camden, New Jersey.

However, “with every retrospective study, there’s potential for bias,” he added. “It doesn’t, in my opinion, give us any definitive answers, but it gets us close to that answer.”

Nevertheless, in the absence of a clear winner, Sansing said, “It’s helpful to know that there’s no wrong way. We haven’t been doing it wrong.”

Yaghi’s group called for large prospective studies to validate their findings.

The study included 63 sites in 16 countries that enrolled their adult patients presenting for acute care of cervical artery dissection that was confirmed by imaging. Incidental or iatrogenic chronic dissection cases, dissecting pseudoaneurysm, and those with major head or neck trauma within the prior 4 weeks were excluded.

In total, 3,636 patients (11.1%) received only therapeutic anticoagulation, whether parental anticoagulation, heparin or low-molecular-weight heparin, oral vitamin K antagonist, or a direct oral anticoagulant. Another 2,453 (67.5%) got exclusively antiplatelets, whether a single or dual antiplatelet regimen. The rest of the cohort crossed over between the two antithrombotic types or received both concurrently.

In subgroup analyses, results were similar between the direct oral anticoagulants and vitamin K antagonists.

Limitations included the retrospective observational design with lack of central and blinded outcome adjudication and likely confounding by indication, although mitigated by inverse probability weighting and propensity matching. Endpoint events were only considered if they happened while on treatment.

Also, Yaghi noted at the session, most sites were large academic institutions, “thus limiting generalizability to small community hospitals.”

author['full_name']

Disclosures

The trial was funded by the National Institute of Neurological Disorders and Stroke and American Heart Association.

Yaghi and Sansing disclosed no relationships with industry.

Jovin disclosed relationships with Cerenovus, Route 92, Galaxy Therapeutics, Methinks, Anaconda , Viz.ai, Kandu Health, StataDX, FreeOx Biotech, Stryker, and Medtronic.

Primary Source

Stroke

Source Reference: Yaghi S, et al “Antithrombotic treatment for stroke prevention in cervical artery dissection: The STOP-CAD study” Stroke 2024; DOI: 10.1161/STROKEAHA.123.045731.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : MedPageToday – https://www.medpagetoday.com/meetingcoverage/isc/108683

Previous Post

What Percent of Nurses Experienced Workplace Violence in 2023?

Next Post

Doing Away With Needle Exchange Programs Won’t Prevent Drug Use

Microplastics and invasive crayfish: emerging interactions and ecological implications from three coexisting species in a subalpine lake – Nature

Uncovering the Hidden Impact: How Microplastics and Invasive Crayfish Interact in a Subalpine Lake Ecosystem

September 30, 2025
Scientists Warn: Bottled Water May Pose Serious Long-Term Health Risks – SciTechDaily

Scientists Reveal Shocking Long-Term Health Risks of Bottled Water

September 30, 2025
You Can Trigger ‘Time Expansion’—Meaning You Can Stretch Seconds and Warp Reality, Scientists Say – Popular Mechanics

Unlock the Secret to Stretching Seconds and Bending Reality: Scientists Reveal How to Trigger ‘Time Expansion

September 30, 2025
Roiserv Lifestyle Services Announces Key Corporate Changes at Upcoming EGM – TipRanks

Roiserv Lifestyle Services Announces Exciting Corporate Overhaul Ahead of Key EGM

September 30, 2025
Saving Energy and Money with Smart Technology – Terms of Service with Clare Duffy – Podcast on CNN Podcasts – CNN

Saving Energy and Money with Smart Technology – Terms of Service with Clare Duffy – Podcast on CNN Podcasts – CNN

September 30, 2025
Tim and Anita Schoen Endow Sport Psychology Program Director Position – Notre Dame Athletics

Tim and Anita Schoen Endow Sport Psychology Program Director Position – Notre Dame Athletics

September 30, 2025
Dodgers feel an urgency to deliver another World Series title to L.A. – Los Angeles Times

Dodgers Fueled by Determination to Bring Another World Series Title to L.A

September 30, 2025
City of Malibu Eases Event and Sign Permitting Requirements to Support Post-Fire Economic Recovery – City of Malibu

Malibu Simplifies Event and Sign Permitting to Boost Post-Fire Economic Recovery

September 30, 2025
The Police Made Chart History With This 1979 Hit Nearly 50 Years Ago – Yahoo

How The Police Changed Music Forever with Their Iconic 1979 Hit Nearly 50 Years Ago

September 30, 2025
WISD weighs in on Michigan Board of Education’s proposed health education changes – WEMU

WISD Takes Action on Proposed Changes to Michigan’s Health Education Standards

September 30, 2025

Categories

Archives

September 2025
M T W T F S S
1234567
891011121314
15161718192021
22232425262728
2930  
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (844)
  • Economy (865)
  • Entertainment (21,739)
  • General (17,331)
  • Health (9,908)
  • Lifestyle (878)
  • News (22,149)
  • People (867)
  • Politics (875)
  • Science (16,075)
  • Sports (21,365)
  • Technology (15,848)
  • World (847)

Recent News

Microplastics and invasive crayfish: emerging interactions and ecological implications from three coexisting species in a subalpine lake – Nature

Uncovering the Hidden Impact: How Microplastics and Invasive Crayfish Interact in a Subalpine Lake Ecosystem

September 30, 2025
Scientists Warn: Bottled Water May Pose Serious Long-Term Health Risks – SciTechDaily

Scientists Reveal Shocking Long-Term Health Risks of Bottled Water

September 30, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version