Recent findings from the Schubert Biochemistry Lab have unveiled novel insights into how specific enzymes regulate cellular health and contribute to disease progression. By employing cutting-edge techniques such as cryo-electron microscopy and real-time kinetic assays, the team successfully identified key molecular interactions that dictate enzyme efficiency and malfunction. These discoveries not only deepen our understanding of enzyme activity at an atomic level but also highlight potential therapeutic targets for complex disorders such as neurodegeneration and metabolic syndromes.

Key Highlights from the Lab’s Latest Research:

  • Identification of allosteric sites influencing enzyme conformation and activity
  • Discovery of enzyme mutations linked to early-onset Parkinson’s disease
  • Development of enzyme modulators that restore normal function in diseased cells
Enzyme Function Disease Association Therapeutic Potential
Kinase-X Cell cycle regulation Breast cancer Selective inhibitors under trial
Hydrolase-Y Protein degradation Alzheimer’s disease Enzyme activators in development
Transferase-Z Metabolic signaling Type II diabetes Small molecule modulators identified