The truth about the new class of Alzheimer’s drugs

Insight and
Health

Three drugs approved for Alzheimer’s disease have been hailed as a breakthrough in treating the condition – how effective are they, and what risks and side effects do they come with?

By Grace Wade

Illustration of amyloid plaques (orange) among brain cells

Science Photo Library/Alamy

In early July, the US Food and Drug Administration (FDA) approved a treatment called donanemab for people with early-stage Alzheimer’s disease. It is the second drug shown to slow the condition’s progression, and the third FDA-authorised medication that clears the amyloid proteins that accumulate in the brains of people with Alzheimer’s.

The FDA’s approval of three new drugs – donanemab, lecanemab and aducanumab – in just over three years has led some to declare a leap forward in Alzheimer’s disease treatment. Japan, South Korea, China,…

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