The use of acupuncture in women undergoing endocrine therapy for hormone receptor (HR)-positive breast cancer resulted in significant improvements in hot flashes and other endocrine symptoms, according to a pooled analysis of randomized trials.
Across the trials conducted in the U.S., China, and South Korea, patients randomized to receive immediate acupuncture reported statistically significant improvements in the Functional Assessment of Cancer Therapy (FACT) endocrine symptom subscale score compared with those in the delayed acupuncture arm (mean change 5.1 vs 0.2, P=0.0003), reported Weidong Lu, MB, MPH, PhD, of the Dana-Farber Cancer Institute in Boston, and colleagues.
Other significant improvements were observed in the hot flash score, calculated by multiplying the frequency and severity of hot flashes recorded in a daily hot flash diary (mean change -5.3 vs -1.4, P
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