* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Sunday, September 28, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Jussie Smollett Claims He Was ‘Disrespected’ on the ‘Special Forces’ Season Premiere – Yahoo

    Jussie Smollett Opens Up About Feeling ‘Disrespected’ During the ‘Special Forces’ Season Premiere

    TicketSmarter Fall Entertainment Guide – Eastern Illinois University Athletics

    TicketSmarter Fall Entertainment Guide – Eastern Illinois University Athletics

    Cardi B Adds More Dates to Little Miss Drama Tour: ‘Y’all Making Me Work’ – Yahoo

    Cardi B Extends Little Miss Drama Tour: “Y’all Making Me Work

    ‘Today’: Sheinelle Jones Thanks Katie Couric for Support After Husband’s Death – CBS 19 News

    Sheinelle Jones Expresses Heartfelt Thanks to Katie Couric for Support After Husband’s Passing

    Sate your hunger at DBA’s Taste of Downtown – Bakersfield.com

    Indulge Your Cravings at DBA’s Taste of Downtown!

    Caesars Entertainment (CZR): Assessing Valuation After Times Square Casino Setback and Mounting Investor Concerns – simplywall.st

    Caesars Entertainment Faces Times Square Casino Hurdles as Investor Concerns Mount

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    From shale to steam: Fossil fuel technology boosts clean geothermal energy – Washington Examiner

    From Shale to Steam: How Fossil Fuel Technology is Powering a Clean Geothermal Energy Revolution

    How Sustainable Technology is Shaping a Greener Future – Technology Magazine

    How Sustainable Technology is Driving the Revolution Toward a Greener Future

    Aurora police hope to add facial recognition technology to crime-fighting tools – CBS News

    Aurora Police Aim to Boost Crime-Fighting with New Facial Recognition Technology

    Autonomous Solutions shows off cutting-edge technology for the public – Cache Valley Daily

    Autonomous Solutions Unveils Cutting-Edge Technology for the Public

    Amazon to Pay $2.5 Billion in Prime Membership Settlement – The New York Times

    Amazon to Pay $2.5 Billion in Prime Membership Settlement – The New York Times

    What are we really gaining from technology? – Fast Company

    What Are We Really Gaining from Technology?

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Jussie Smollett Claims He Was ‘Disrespected’ on the ‘Special Forces’ Season Premiere – Yahoo

    Jussie Smollett Opens Up About Feeling ‘Disrespected’ During the ‘Special Forces’ Season Premiere

    TicketSmarter Fall Entertainment Guide – Eastern Illinois University Athletics

    TicketSmarter Fall Entertainment Guide – Eastern Illinois University Athletics

    Cardi B Adds More Dates to Little Miss Drama Tour: ‘Y’all Making Me Work’ – Yahoo

    Cardi B Extends Little Miss Drama Tour: “Y’all Making Me Work

    ‘Today’: Sheinelle Jones Thanks Katie Couric for Support After Husband’s Death – CBS 19 News

    Sheinelle Jones Expresses Heartfelt Thanks to Katie Couric for Support After Husband’s Passing

    Sate your hunger at DBA’s Taste of Downtown – Bakersfield.com

    Indulge Your Cravings at DBA’s Taste of Downtown!

    Caesars Entertainment (CZR): Assessing Valuation After Times Square Casino Setback and Mounting Investor Concerns – simplywall.st

    Caesars Entertainment Faces Times Square Casino Hurdles as Investor Concerns Mount

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    From shale to steam: Fossil fuel technology boosts clean geothermal energy – Washington Examiner

    From Shale to Steam: How Fossil Fuel Technology is Powering a Clean Geothermal Energy Revolution

    How Sustainable Technology is Shaping a Greener Future – Technology Magazine

    How Sustainable Technology is Driving the Revolution Toward a Greener Future

    Aurora police hope to add facial recognition technology to crime-fighting tools – CBS News

    Aurora Police Aim to Boost Crime-Fighting with New Facial Recognition Technology

    Autonomous Solutions shows off cutting-edge technology for the public – Cache Valley Daily

    Autonomous Solutions Unveils Cutting-Edge Technology for the Public

    Amazon to Pay $2.5 Billion in Prime Membership Settlement – The New York Times

    Amazon to Pay $2.5 Billion in Prime Membership Settlement – The New York Times

    What are we really gaining from technology? – Fast Company

    What Are We Really Gaining from Technology?

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Adenovirus May Trigger Thrombocytopenia, Thrombosis, Case Studies Suggest

August 10, 2023
in Health
Adenovirus May Trigger Thrombocytopenia, Thrombosis, Case Studies Suggest
Share on FacebookShare on Twitter

In rare cases, symptomatic human adenovirus infection may trigger a life-threatening prothrombotic anti-platelet factor 4 (PF4) disorder resembling vaccine-induced immune thrombotic thrombocytopenia (VITT), according to a report based on two patients.

A 5-year-old boy and a 58-year-old woman based in the U.S. developed serious — and in the case of the boy, ultimately fatal — thrombocytopenia and one or more thrombotic events after being infected with an adenovirus, reported Theodore E. Warkentin, MD, of McMaster University in Hamilton, Ontario, and colleagues in a New England Journal of Medicine correspondence.

Both patients had nasopharyngeal swap samples that tested positive for human adenovirus and negative for 18 other pathogens, including SARS-C0V-2.

Gastrointestinal symptoms occurred in the child, respiratory symptoms occurred in the woman, and both experienced fever. These symptoms were followed 5 to 6 days later by severe thrombocytopenia, coagulopathy, and thrombotic events — fatal cerebral venous sinus thrombosis in the child and multiple arterial strokes, ST-segment elevation myocardial infarction, and multiple deep-vein thromboses in the woman.

Neither patient had previously been exposed to heparin, which is associated with thrombocytopenia (heparin-induced thrombocytopenia [HIT]).

Multiple anti-PF4 assays found VITT-like antibodies to PF4 in serum samples obtained from both patients.

“That is, they are almost identical with the antibodies that were implicated in the COVID-19 vaccine reactions seen in the last few years,” Warkentin told MedPage Today.

VITT is characterized by thrombosis at atypical sites combined with thrombocytopenia. In early 2021, VITT was observed in multiple patients soon after they received the AstraZeneca COVID vaccine. By April of that year, it was also reported in patients who received the Johnson & Johnson vaccine. The woman in this series had been vaccinated against COVID-19 with the Moderna shot 15 months before her adenovirus infection; the mRNA vaccines have not been associated with VITT.

“What made these observations super striking was that both patients developed this VITT-like disorder approximately a week after getting symptomatic adenovirus infection,” Warkentin said. “And the reason that got our attention, and the attention of the editors at the New England Journal of Medicine, is that the vaccines that caused VITT are adenoviral vector vaccines, so it seemed like more than a coincidence that the adenovirus is central to the type of vaccines that were developed to fight COVID-19, and in rare instances caused the VITT reaction.”

“To our knowledge, no one has ever reported that adenovirus infections cause prothrombotic disorder with low platelets, clotting, and anti-PF4 antibodies,” he added. “So that’s the first time that this triad has been put together after an adenovirus infection — so it’s a novel finding.”

Warkentin noted that if a patient presents with thrombocytopenia and thrombosis, clinicians should consider an anti-PF4 disorder as a possible explanation.

“If someone has thrombocytopenia and thrombosis, and a history of viral illness a week or two earlier, that should probably become a leading potential diagnosis,” he said, pointing out that the treatment for this condition will be important.

“Obviously [with] thrombosis, you want to give a blood thinner, so that’s not a surprise,” he added. “But we know from the VITT literature that it’s important to block the antibody’s ability to activate the platelets, and we do that with high-dose intravenous immunoglobulin, and that’s a different treatment you normally don’t use for treating thrombosis. But, in this type of disorder, you need to give it. So right off the bat, it’s an important disorder that has its own unique treatment approach.”

Warkentin suggested that — in hindsight — this disorder associated with adenovirus infection has “been going on for years, decades, centuries.”

“What’s really interesting is that in my practice as a hematologist I have been aware in the past of patients who did develop viral illnesses and a week or so later developed low platelets and blood clotting,” he noted. Thus, he said that he and his colleagues believe an adenovirus can — very rarely — trigger an anti-PF4 disorder.

The onset of the COVID pandemic, and the rare appearance of VITT after hundreds of millions of people were vaccinated over a short period of time, led laboratories like Warkentin’s to study VITT and recognize VITT antibodies and distinguish them from HIT antibodies.

“And we learned how to detect good antibodies,” he explained. “So now that we’ve learned how to detect good antibodies, when patients get these antibodies due to other triggers — for example, adenovirus infection — we now know how to identify them. So, in a way, VITT has allowed us to recognize something that probably has been happening sporadically — and rarely — for years.”

author['full_name']

Mike Bassett is a staff writer focusing on oncology and hematology. He is based in Massachusetts.

Disclosures

Warkentin reported consulting for Paradigm Pharmaceuticals, Veralox Therapeutics, and Werfen USA.

Primary Source

New England Journal of Medicine

Source Reference: Warkentin TE, et al “Adenovirus-associated thrombocytopenia, thrombosis, and VITT-like antibodies” N Engl J Med 2023; DOI: 10.1056/NEJMc2307721.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : MedPageToday – https://www.medpagetoday.com/infectiousdisease/generalinfectiousdisease/105826

Tags: AdenovirushealthTrigger
Previous Post

Dementia Risk Linked With Cumulative Heartburn Med Use, Analysis Suggests

Next Post

Anti-Androgens Can Be Used for PCOS When Oral Contraceptives Can’t

While chasing DK Metcalf, Isaiah Rodgers reached unprecedented speed – Yahoo Sports

Isaiah Rodgers Hits Unbelievable Top Speed While Chasing Down DK Metcalf

September 28, 2025
Poland bounce back with first ever World Championship bronze – Volleyball World

Poland Triumphs with Historic First-Ever World Championship Bronze in Volleyball

September 28, 2025

Russian Economy Struggles Under Growing Strain of Ukraine Conflict

September 28, 2025
Jussie Smollett Claims He Was ‘Disrespected’ on the ‘Special Forces’ Season Premiere – Yahoo

Jussie Smollett Opens Up About Feeling ‘Disrespected’ During the ‘Special Forces’ Season Premiere

September 28, 2025
Tom Holland shares health update after suffering concussion on ‘Spider-Man: Brand New Day’ set – New York Post

Tom Holland Opens Up About His Recovery After Concussion on ‘Spider-Man: Brand New Day’ Set

September 28, 2025
Politics are destroying our public schools. It doesn’t have to be that way | Opinion – Pensacola News Journal

How Politics Are Undermining Our Public Schools-and What We Can Do About It

September 28, 2025
Featured in Functional Ecology – besjournals

Discover the Latest Breakthroughs in Functional Ecology

September 28, 2025
Scientists Identify Simple and Effective Way To Reduce Calorie Intake Without Trying – SciTechDaily

Scientists Identify Simple and Effective Way To Reduce Calorie Intake Without Trying – SciTechDaily

September 28, 2025
Million-year-old skull rewrites human evolution, say scientists – BBC

Ancient Skull Discovery Upends Our Understanding of Human Evolution

September 28, 2025
Corgi Can’t Stop Slipping & TikTok Can’t Stop Laughing – Yahoo

Corgi’s Hilarious Slips Have Everyone Laughing Out Loud

September 28, 2025

Categories

Archives

September 2025
M T W T F S S
1234567
891011121314
15161718192021
22232425262728
2930  
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (841)
  • Economy (862)
  • Entertainment (21,736)
  • General (17,293)
  • Health (9,905)
  • Lifestyle (874)
  • News (22,149)
  • People (863)
  • Politics (872)
  • Science (16,071)
  • Sports (21,362)
  • Technology (15,844)
  • World (844)

Recent News

While chasing DK Metcalf, Isaiah Rodgers reached unprecedented speed – Yahoo Sports

Isaiah Rodgers Hits Unbelievable Top Speed While Chasing Down DK Metcalf

September 28, 2025
Poland bounce back with first ever World Championship bronze – Volleyball World

Poland Triumphs with Historic First-Ever World Championship Bronze in Volleyball

September 28, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version