* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Tuesday, August 26, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    ‘The Roses’ review: Olivia Colman, Benedict Cumberbatch sparkle in dark comedy – Yakima Herald-Republic

    The Roses’ Review: Olivia Colman and Benedict Cumberbatch Shine in Dark Comedy Delight

    ‘When Calls the Heart’ Fans All Want the Same Thing After Seeing the Show’s Latest Update – yahoo.com

    When Calls the Heart’ Fans Rally Together in Excitement Over Exciting New Update!

    Quotes of the Week: Peacemaker, Project Runway, Countdown and More – yahoo.com

    This Week’s Most Memorable Quotes from Peacemaker, Project Runway, Countdown, and More!

    Drake Appears in Teaser for Bobbi Althoff’s New Podcast ‘Not This Again’ – yahoo.com

    Drake Drops a Surprise Cameo in Bobbi Althoff’s Thrilling New Podcast Teaser ‘Not This Again

    From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

    From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

    How to watch ‘F1: The Movie’ on Prime Video – About Amazon

    Experience the Thrill: How to Stream ‘F1: The Movie’ on Prime Video

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    The Role of AI and Technology in Shaping the Future of Interactive Entertainment – Technology Org

    How AI and Technology Are Transforming the Future of Interactive Entertainment

    Ten upcoming sports stadiums where technology takes to the field – Dezeen

    10 Futuristic Sports Stadiums Revolutionizing the Game with Cutting-Edge Technology

    Figure Technology Solutions, Inc. Files Registration Statement for Proposed Initial Public Offering – Business Wire

    Figure Technology Solutions, Inc. Unveils Exciting Plans for Its Upcoming Initial Public Offering

    UNLV Responds to Workforce Need with Microcredential in Nuclear Technology – University of Nevada, Las Vegas | UNLV

    UNLV Unveils Cutting-Edge Microcredential Program to Fuel Growth in Nuclear Technology

    Why Technology Will Never Take Over Completely – Patheos

    Why Technology Will Never Completely Control Our Lives

    Alcorn State awarded grant to boost STEM with VR technology – WJTV

    Alcorn State Secures Grant to Transform STEM Education Through Cutting-Edge VR Technology

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    ‘The Roses’ review: Olivia Colman, Benedict Cumberbatch sparkle in dark comedy – Yakima Herald-Republic

    The Roses’ Review: Olivia Colman and Benedict Cumberbatch Shine in Dark Comedy Delight

    ‘When Calls the Heart’ Fans All Want the Same Thing After Seeing the Show’s Latest Update – yahoo.com

    When Calls the Heart’ Fans Rally Together in Excitement Over Exciting New Update!

    Quotes of the Week: Peacemaker, Project Runway, Countdown and More – yahoo.com

    This Week’s Most Memorable Quotes from Peacemaker, Project Runway, Countdown, and More!

    Drake Appears in Teaser for Bobbi Althoff’s New Podcast ‘Not This Again’ – yahoo.com

    Drake Drops a Surprise Cameo in Bobbi Althoff’s Thrilling New Podcast Teaser ‘Not This Again

    From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

    From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

    How to watch ‘F1: The Movie’ on Prime Video – About Amazon

    Experience the Thrill: How to Stream ‘F1: The Movie’ on Prime Video

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    The Role of AI and Technology in Shaping the Future of Interactive Entertainment – Technology Org

    How AI and Technology Are Transforming the Future of Interactive Entertainment

    Ten upcoming sports stadiums where technology takes to the field – Dezeen

    10 Futuristic Sports Stadiums Revolutionizing the Game with Cutting-Edge Technology

    Figure Technology Solutions, Inc. Files Registration Statement for Proposed Initial Public Offering – Business Wire

    Figure Technology Solutions, Inc. Unveils Exciting Plans for Its Upcoming Initial Public Offering

    UNLV Responds to Workforce Need with Microcredential in Nuclear Technology – University of Nevada, Las Vegas | UNLV

    UNLV Unveils Cutting-Edge Microcredential Program to Fuel Growth in Nuclear Technology

    Why Technology Will Never Take Over Completely – Patheos

    Why Technology Will Never Completely Control Our Lives

    Alcorn State awarded grant to boost STEM with VR technology – WJTV

    Alcorn State Secures Grant to Transform STEM Education Through Cutting-Edge VR Technology

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Aided by AI, new catheter design helps prevent bacterial infections

January 6, 2024
in Health
Aided by AI, new catheter design helps prevent bacterial infections
Share on FacebookShare on Twitter

Aided by AI, new catheter design prevents bacterial infections

Schematic of proposed CAUTI mechanism and anti-infection design process. (A) Proposed mechanism for CAUTI. The urine flows from within the patient’s bladder outward through a catheter, while bacteria swim upstream into the patient’s body. (B) The run-and-tumble motion of bacteria and upstream swimming mechanism. (C) Simulations to explore catheter shapes suppressing upstream swimming. (D) AI-assisted optimization using the geo-FNO framework. (E) Microfluidic experiments to test the design in 2D channels. (F) 3D experiment with designed real-size catheters. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adj1741

Bacteria are remarkably good swimmers—a trait that can be detrimental to human health. One of the most common bacterial infections in a health care setting comes from bacteria entering the body through catheters, thin tubes inserted in the urinary tract. Though catheters are designed to draw fluids out of a patient, bacteria are able to propel themselves upstream and into the body via catheter tubes using a unique swimming motion, causing $300 million of catheter-associated urinary infections in the U.S. annually.

Now, an interdisciplinary project at Caltech has designed a new type of catheter tube that impedes the upstream mobility of bacteria, without the need for antibiotics or other chemical antimicrobial methods. With the new design, which was optimized by novel artificial intelligence (AI) technology, the number of bacteria that are able to swim upstream in laboratory experiments was reduced 100-fold.

The paper, “AI-aided geometric design of anti-infection catheters,” was published in the journal Science Advances on January 3.

In catheter tubes, fluid exhibits a so-called Poiseuille flow, an effect where fluid movement is faster in the center but slow near the wall, similar to the flow in a river’s current, where the velocity of the water varies from fast in the center to slow near the banks. Bacteria, as self-propelling organisms, exhibit a unique “two-step forward along the wall, one-step back in the middle” motion that produces their forward progress in tubular structures. Researchers in the Brady lab had previously modeled this phenomenon.

“One day, I shared this intriguing phenomenon with Chiara Daraio, framing it simply as a ‘cool thing,’ and her response shifted the conversation toward a practical application,” says Tingtao Edmond Zhou, postdoctoral scholar in chemical engineering and a co-first author of the study. “Chiara’s research often plays with all kinds of interesting geometries, and she suggested tackling this problem with simple geometries.”

Following that suggestion, the team designed tubes with triangular protrusions, like shark fins, along the inside of the tube’s walls. Simulations yielded promising results: These geometric structures effectively redirected bacterial movement, propelling them toward the center of the tube where the faster flow pushed them back downstream. The triangles’ fin-like curvature also generated vortices that further disrupted bacterial progress.

Zhou and his collaborators aimed to verify the design experimentally but needed additional biology expertise. For that, Zhou reached out to Olivia Xuan Wan, a postdoctoral scholar in the Sternberg laboratory.

“I study nematode navigation, and this project resonated deeply with my specialized interest in motion trajectories,” says Wan, who is also a co-first author on the new paper. For years, the Sternberg laboratory has conducted research into the navigation mechanisms of the nematode Caenorhabditis elegans, a rice grain–sized soil organism commonly studied in research labs and thus had many of the tools to observe and analyze the movements of microscopic organisms.

The team quickly transitioned from theoretical modeling to practical experimentation, using 3D printed catheter tubes and high-speed cameras to monitor bacterial progress. The tubes with triangular inclusions resulted in a reduction of upstream bacterial movement by two orders of magnitude (a 100-fold decrease).

The team then continued simulations to determine the most effective triangular obstacle shape to impede bacteria’s upstream swimming. They then fabricated microfluidic channels analogous to common catheter tubes with the optimized triangular designs to observe the movement of E. coli bacteria under various flow conditions. The observed trajectories of the E. coli within these microfluidic environments aligned almost perfectly with the simulated predictions.

The collaboration grew as the researchers aimed to continue improving the geometric tube design. Artificial intelligence experts in the Anandkumar laboratory provided the project with cutting-edge AI methods called neural operators.

This technology was able to accelerate the catheter design optimization computations so they required not days but minutes. The resulting model proposed tweaks to the geometric design, further optimizing the triangle shapes to prevent even more bacteria from swimming upstream. The final design enhanced the efficacy of the initial triangular shapes by an additional 5% in simulations.

“Our journey from theory to simulation, experiment, and, finally, to real-time monitoring within these microfluidic landscapes is a compelling demonstration of how theoretical concepts can be brought to life, offering tangible solutions to real-world challenges,” says Zhou.

More information:
Tingtao Zhou et al, AI-aided geometric design of anti-infection catheters, Science Advances (2024). DOI: 10.1126/sciadv.adj1741

Citation:
Aided by AI, new catheter design helps prevent bacterial infections (2024, January 5)
retrieved 6 January 2024
from https://medicalxpress.com/news/2024-01-aided-ai-catheter-bacterial-infections.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2024-01-aided-ai-catheter-bacterial-infections.html

Tags: Aidedcatheterhealth
Previous Post

Researchers investigate why vaccines don’t work as well in some older adults

Next Post

For Black adolescents, feeling connected to school has long-lasting mental health benefits, researchers find

Why Your Subway System Isn’t Ready for Today’s Challenges

August 26, 2025
Considering the economic impact of the President’s law enforcement measures in DC – Federal News Network

How the President’s Law Enforcement Actions Are Shaping DC’s Economy

August 26, 2025
What Were Andy Griffith’s Last Words to Don Knotts? – Cadillac News

What Were Andy Griffith’s Final Words to Don Knotts?

August 26, 2025
Heinrich, Leger Fernández ask key U.S. health official to visit struggling Gallup Indian Medical Center – Santa Fe New Mexican

Heinrich, Leger Fernández ask key U.S. health official to visit struggling Gallup Indian Medical Center – Santa Fe New Mexican

August 26, 2025
Kilmar Ábrego García speaks out before entering ICE facility – CNN

Kilmar Ábrego García Breaks Silence Ahead of ICE Detention

August 26, 2025
WA Ecology official testifies against repeal of ‘endangerment finding’ that allows for climate regulation – The Spokesman-Review

WA Ecology official testifies against repeal of ‘endangerment finding’ that allows for climate regulation – The Spokesman-Review

August 26, 2025
Bishop Kearney girls’ hockey team partners with UR Medicine for science-based training – 13wham.com

Bishop Kearney Girls’ Hockey Team Teams Up with UR Medicine for Cutting-Edge Science-Based Training

August 26, 2025
STEM camps offered at National Museum of Nuclear Science and History – KRQE

Discover Thrilling STEM Camps Now Open at the National Museum of Nuclear Science and History!

August 26, 2025
7 things people do when they care too much about what others think – VegOut

7 Signs You’re Caring Too Much About What Others Think

August 26, 2025
The Role of AI and Technology in Shaping the Future of Interactive Entertainment – Technology Org

How AI and Technology Are Transforming the Future of Interactive Entertainment

August 26, 2025

Categories

Archives

August 2025
MTWTFSS
 123
45678910
11121314151617
18192021222324
25262728293031
« Jul    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (790)
  • Economy (810)
  • Entertainment (21,689)
  • General (16,678)
  • Health (9,851)
  • Lifestyle (823)
  • News (22,149)
  • People (811)
  • Politics (818)
  • Science (16,020)
  • Sports (21,309)
  • Technology (15,791)
  • World (792)

Recent News

Why Your Subway System Isn’t Ready for Today’s Challenges

August 26, 2025
Considering the economic impact of the President’s law enforcement measures in DC – Federal News Network

How the President’s Law Enforcement Actions Are Shaping DC’s Economy

August 26, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version