* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Thursday, June 26, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    George Lopez is coming to Spokane – KXLY.com

    George Lopez is coming to Spokane – KXLY.com

    Netflix unveils Dallas immersive venue for fans of hit shows like ‘Squid Game,’ ‘Stranger Things’ – Houston Chronicle

    Step Inside Netflix’s New Dallas Immersive Experience Featuring Hits Like ‘Squid Game’ and ‘Stranger Things

    ‘Puttin’ on the Ritz’: Civic Players bring ‘Young Frankenstein’ to life – Yahoo

    Civic Players Deliver a Hilarious and Unforgettable Performance of ‘Young Frankenstein

    ‘Wheel of Fortune’: Amputee Wins $60,000 After Breaking Incredible ‘Curse’ – Hastings Tribune

    Wheel of Fortune’ Amputee Breaks Incredible ‘Curse’ to Win $60,000!

    North Star Sports & Entertainment Network: Coming soon – KTTC News

    North Star Sports & Entertainment Network: Coming soon – KTTC News

    Safety concerns in Deep Ellum create apprehension as the entertainment district gains visitors – CBS News

    Safety Concerns Surge Amid Deep Ellum’s Booming Popularity and Growing Crowds

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Frontdoor Announces Tech Expert Dr. Bala Ganesh as Chief Technology Officer – Business Wire

    Frontdoor Appoints Tech Visionary Dr. Bala Ganesh as New Chief Technology Officer

    Defense technology giant Northrop Grumman to host interviews in Iuka to fill technician roles – supertalk.fm

    Defense technology giant Northrop Grumman to host interviews in Iuka to fill technician roles – supertalk.fm

    China’s Military Introduces Mosquito-Sized Drones: A Game-Changing Surveillance Technology – Indian Defence Review

    China Unveils Mosquito-Sized Drones: Revolutionizing Surveillance Technology

    Marvell Technology Stock Rallies After AI Event Sparks Investor Optimism – Yahoo Finance

    Marvell Technology Stock Rallies After AI Event Sparks Investor Optimism – Yahoo Finance

    Promising Technology Stocks To Follow Today – June 22nd – MarketBeat

    Top Technology Stocks to Watch Today – June 22nd

    Technology Convergence Report 2025 – The World Economic Forum

    Technology Convergence Report 2025 – The World Economic Forum

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    George Lopez is coming to Spokane – KXLY.com

    George Lopez is coming to Spokane – KXLY.com

    Netflix unveils Dallas immersive venue for fans of hit shows like ‘Squid Game,’ ‘Stranger Things’ – Houston Chronicle

    Step Inside Netflix’s New Dallas Immersive Experience Featuring Hits Like ‘Squid Game’ and ‘Stranger Things

    ‘Puttin’ on the Ritz’: Civic Players bring ‘Young Frankenstein’ to life – Yahoo

    Civic Players Deliver a Hilarious and Unforgettable Performance of ‘Young Frankenstein

    ‘Wheel of Fortune’: Amputee Wins $60,000 After Breaking Incredible ‘Curse’ – Hastings Tribune

    Wheel of Fortune’ Amputee Breaks Incredible ‘Curse’ to Win $60,000!

    North Star Sports & Entertainment Network: Coming soon – KTTC News

    North Star Sports & Entertainment Network: Coming soon – KTTC News

    Safety concerns in Deep Ellum create apprehension as the entertainment district gains visitors – CBS News

    Safety Concerns Surge Amid Deep Ellum’s Booming Popularity and Growing Crowds

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Frontdoor Announces Tech Expert Dr. Bala Ganesh as Chief Technology Officer – Business Wire

    Frontdoor Appoints Tech Visionary Dr. Bala Ganesh as New Chief Technology Officer

    Defense technology giant Northrop Grumman to host interviews in Iuka to fill technician roles – supertalk.fm

    Defense technology giant Northrop Grumman to host interviews in Iuka to fill technician roles – supertalk.fm

    China’s Military Introduces Mosquito-Sized Drones: A Game-Changing Surveillance Technology – Indian Defence Review

    China Unveils Mosquito-Sized Drones: Revolutionizing Surveillance Technology

    Marvell Technology Stock Rallies After AI Event Sparks Investor Optimism – Yahoo Finance

    Marvell Technology Stock Rallies After AI Event Sparks Investor Optimism – Yahoo Finance

    Promising Technology Stocks To Follow Today – June 22nd – MarketBeat

    Top Technology Stocks to Watch Today – June 22nd

    Technology Convergence Report 2025 – The World Economic Forum

    Technology Convergence Report 2025 – The World Economic Forum

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

American Guidelines Sour on Beta-Blockers for Chronic Coronary Disease

July 21, 2023
in Health
American Guidelines Sour on Beta-Blockers for Chronic Coronary Disease
Share on FacebookShare on Twitter

New American guidelines for chronic coronary disease (CCD) modify management considerations for a heterogeneous group that includes people with or without angina, a history of coronary revascularization, and previous acute coronary syndrome.

For one, the American Heart Association (AHA) and American College of Cardiology (ACC) say that outpatients with CCD should no longer initiate beta-blockers — based on recent observational studies, a class III statement of non-recommendation has been issued for long-term beta-blocker therapy in the absence of myocardial infarction (MI) in the past year, left ventricular ejection fraction ≤50%, or another primary indication for beta-blocker therapy.

“This guideline provides an evidenced-based and patient-centered approach to management of patients with chronic coronary disease, considering social determinants of health and incorporating the principles of shared decision-making and team-based care,” according to the writing committee chaired by Salim Virani, MD, PhD, of the Aga Khan University in Karachi City, Pakistan, and Texas Heart Institute, Houston.

Published in Circulation, the new recommendations replace the 2012 guideline and 2014 focused guideline update on stable ischemic heart disease.

Virani and colleagues noted that CCD covers conditions of obstructive and nonobstructive coronary artery disease (CAD) with or without previous MI or revascularization, ischemic heart disease diagnosed only by noninvasive testing, and chronic angina syndromes with varying underlying causes. Approximately 20.1 million people live with CCD in the U.S., they said.

In patients with CCD who are already on beta-blockers for previous MI without a history of or current left ventricular ejection fraction (LVEF) ≤50%, angina, arrhythmias, or uncontrolled hypertension, guideline authors deem it “may be reasonable” to reassess the indication for long-term use of beta-blocker therapy for reducing major adverse cardiovascular events, in a class IIb recommendation.

Meanwhile, modified recommendations now put a class I endorsement for revascularization to improve symptoms in patients with lifestyle-limiting angina despite guideline-directed medical therapy and with coronary stenoses amenable to revascularization; or to improve survival in patients with significant left main disease, or multivessel disease with severe left ventricular (LV) dysfunction in whom bypass surgery plus medical therapy is recommended over medical therapy alone.

The AHA and ACC continue to recommend healthy diet and exercise. Statins remain the first-line therapy for lipid lowering; this leaves ezetimibe (Zetia), PCSK9 inhibitors, inclisiran (Leqvio), and bempedoic acid (Nexletol) as adjunctive therapies with weaker class II endorsements.

Meanwhile, SGLT-2 inhibitors are strongly recommended for those with CCD and type 2 diabetes or heart failure with reduced LVEF, and GLP-1 receptor agonists are similarly endorsed in CCD with type 2 diabetes.

Routine periodic anatomic or ischemic testing should be limited to people who have had a change in clinical or functional status, not for risk stratification or to guide therapeutic decision-making in patients with CCD.

“There is no role for routine stress testing or coronary angiography in patients who are stable,” agreed Sunil Rao, MD, and two colleagues at NYU Langone Health System in New York City, in an accompanying editorial.

“Although not specifically mentioned in the guidelines, as a pragmatic approach, periodic assessment of LV function might be considered for patients with LVEF near the qualifying value for an implantable cardioverter-defibrillator, even without a change in clinical status. Otherwise, there is no role for routine assessment of LV function,” the editorialists wrote.

As for the soured attitude toward beta-blockers, Rao and colleagues noted that this is based on observational data and that several ongoing randomized trials are assessing how well beta-blockers work in the context of contemporary secondary prevention in a range of CCD patient types.

“Importantly, the guidelines exist to provide guidance, and are meant to complement, not supplant, clinical judgment. As the evidence for the management of CCD continues to evolve, the guidelines will need to be a ‘living document’ to ensure that clinicians and patients can achieve their shared therapeutic goals of reducing mortality and improving quality of life,” they urged.

The new guidelines had been developed in collaboration with and were endorsed by the American College of Clinical Pharmacy, American Society for Preventive Cardiology, National Lipid Association, and Preventive Cardiovascular Nurses Association; and were endorsed by the Society for Cardiovascular Angiography and Interventions.

author['full_name']

Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow

Disclosures

Virani and Rao had no relevant disclosures.

Primary Source

Circulation

Source Reference: Virani SS, et al “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA guideline for the management of patients with chronic coronary disease: A report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines” Circulation 2023; DOI: 10.1161/CIR.0000000000001168.

Secondary Source

Circulation

Source Reference: Rao SV, et al “Chronic coronary disease guidelines” Circulation 2023; DOI: 10.1161/CIRCULATIONAHA.123.064623.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : MedPageToday – https://www.medpagetoday.com/cardiology/prevention/105574

Tags: Americanguidelineshealth
Previous Post

Cost of Wasted Cancer Drugs May Exceed $4,000 Per Patient

Next Post

Nixing Food Triggers Could Ease More Eosinophilic GI Disorders

HUD to move into the National Science Foundation headquarters, no current plan on where to relocate NSF employees – Government Executive

HUD to move into the National Science Foundation headquarters, no current plan on where to relocate NSF employees – Government Executive

June 25, 2025

Protecting the Boundless Future of U.S. Science: Tackling Tomorrow’s Challenges Today

June 25, 2025
LVMH’s Paris Olympics partnership wins Luxury and Lifestyle Grand Prix – Ad Age

LVMH Shines Bright with Luxury and Lifestyle Victory at Paris Olympics Partnership

June 25, 2025
Why the Strait of Hormuz, A Vital Oil Route, Is Vulnerable to Israel-Iran Conflict – The New York Times

Why the Strait of Hormuz, A Vital Oil Route, Is Vulnerable to Israel-Iran Conflict – The New York Times

June 25, 2025
Dying honey bees are threatening California’s economy. Can Central Valley lawmakers save them? – CalMatters

Dying honey bees are threatening California’s economy. Can Central Valley lawmakers save them? – CalMatters

June 25, 2025
Butler launches sports, entertainment institute focused on local events – Inside INdiana Business

Butler Launches Exciting New Sports and Entertainment Institute Spotlighting Local Events

June 25, 2025
Expert panel picked by RFK Jr. will scrutinize the vaccine schedule for kids – NPR

Expert panel picked by RFK Jr. will scrutinize the vaccine schedule for kids – NPR

June 25, 2025
What Is a Democratic Socialist? – The New York Times

What Is a Democratic Socialist? – The New York Times

June 25, 2025
Frontdoor Announces Tech Expert Dr. Bala Ganesh as Chief Technology Officer – Business Wire

Frontdoor Appoints Tech Visionary Dr. Bala Ganesh as New Chief Technology Officer

June 25, 2025
City council approves Sports Illustrated Resort – WBRC 6 News

City Council Approves Exciting New Sports Illustrated Resort Project

June 25, 2025

Categories

Archives

June 2025
MTWTFSS
 1
2345678
9101112131415
16171819202122
23242526272829
30 
« May    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (698)
  • Economy (717)
  • Entertainment (21,612)
  • General (15,564)
  • Health (9,756)
  • Lifestyle (722)
  • News (22,149)
  • People (719)
  • Politics (724)
  • Science (15,935)
  • Sports (21,213)
  • Technology (15,702)
  • World (697)

Recent News

HUD to move into the National Science Foundation headquarters, no current plan on where to relocate NSF employees – Government Executive

HUD to move into the National Science Foundation headquarters, no current plan on where to relocate NSF employees – Government Executive

June 25, 2025

Protecting the Boundless Future of U.S. Science: Tackling Tomorrow’s Challenges Today

June 25, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version