* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Monday, September 1, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

    Erykah Badu Announces ‘Abi & Alan’ Album With The Alchemist Will Be Delayed – yahoo.com

    Erykah Badu Opens Up About the Delay of Her Highly Anticipated ‘Abi & Alan’ Album with The Alchemist

    If You Needed Some BTS Pics Of The Rock’s Tree Trunk Legs To Spice Up Your Day, We Got ‘Em – yahoo.com

    Need a Boost? Check Out These Epic BTS Shots of The Rock’s Tree Trunk Legs!

    Sabrina Carpenter’s pearl-clutching magic? Humor – CNN

    Sabrina Carpenter’s pearl-clutching magic? Humor – CNN

    South Park Is In Trouble And Needs To Change Course, Fast – yahoo.com

    South Park Faces Major Challenges and Must Adapt Fast to Survive

    ‘Netflix House’ entertainment complexes are coming. Here’s when they open – Los Angeles Times

    Exciting News: Netflix’s House Entertainment Complexes Are Opening Soon!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

    How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

    Gator football kicks off with excitement and new technology – WCJB | TV20

    Gator Football Kicks Off with Thrilling Action and Innovative Technology

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Propelling solar technology into a perovskite future – CORDIS

    Propelling solar technology into a perovskite future – CORDIS

    13 Top Technology Trends (2025) – Exploding Topics

    13 Game-Changing Technology Trends to Watch in 2025

    Japan’s legacy LCD and chip technology find new home in India – Nikkei Asia

    How Japan’s Breakthrough LCD and Chip Technologies Are Driving Innovation in India

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

    Erykah Badu Announces ‘Abi & Alan’ Album With The Alchemist Will Be Delayed – yahoo.com

    Erykah Badu Opens Up About the Delay of Her Highly Anticipated ‘Abi & Alan’ Album with The Alchemist

    If You Needed Some BTS Pics Of The Rock’s Tree Trunk Legs To Spice Up Your Day, We Got ‘Em – yahoo.com

    Need a Boost? Check Out These Epic BTS Shots of The Rock’s Tree Trunk Legs!

    Sabrina Carpenter’s pearl-clutching magic? Humor – CNN

    Sabrina Carpenter’s pearl-clutching magic? Humor – CNN

    South Park Is In Trouble And Needs To Change Course, Fast – yahoo.com

    South Park Faces Major Challenges and Must Adapt Fast to Survive

    ‘Netflix House’ entertainment complexes are coming. Here’s when they open – Los Angeles Times

    Exciting News: Netflix’s House Entertainment Complexes Are Opening Soon!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

    How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

    Gator football kicks off with excitement and new technology – WCJB | TV20

    Gator Football Kicks Off with Thrilling Action and Innovative Technology

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Propelling solar technology into a perovskite future – CORDIS

    Propelling solar technology into a perovskite future – CORDIS

    13 Top Technology Trends (2025) – Exploding Topics

    13 Game-Changing Technology Trends to Watch in 2025

    Japan’s legacy LCD and chip technology find new home in India – Nikkei Asia

    How Japan’s Breakthrough LCD and Chip Technologies Are Driving Innovation in India

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Benign nail condition linked to rare syndrome that greatly increases cancer risk

May 20, 2024
in Health
Benign nail condition linked to rare syndrome that greatly increases cancer risk
Share on FacebookShare on Twitter

Benign nail condition linked to rare syndrome that greatly increases cancer risk

A fingernail with onychopapilloma. Credit: Dermatology Consultation Service, NIAMS

Scientists at the National Institutes of Health (NIH) have discovered that the presence of a benign nail abnormality may lead to the diagnosis of a rare inherited disorder that increases the risk of developing cancerous tumors of the skin, eyes, kidneys and the tissue that lines the chest and abdomen (e.g., the mesothelium).

The condition, known as BAP1 tumor predisposition syndrome, is caused by mutations in the BAP1 gene, which normally acts as a tumor suppressor, among other functions.

The findings are published in JAMA Dermatology and were presented at the Society for Investigative Dermatology Annual Meeting (SID 2024) that was held in Dallas May 15–18.

Scientists happened upon the discovery while studying participants who were enrolled in a screening for BAP 1 variants at the NIH Clinical Center. As part of the study, a dermatology screening was performed at enrollment and annually for participants aged 2 and older. The cohort in the current study included 47 individuals with BAP1 tumor predisposition syndrome from 35 families.

“When asked about nail health during a baseline genetic assessment, a very astute patient reported that he had noticed subtle changes in his nails,” said co-lead author and genetic counselor Alexandra Lebensohn, M.S., of NIH’s National Cancer Institute (NCI). “His comment prompted us to systematically evaluate other participants for nail changes and uncover this new finding.”

Biopsies of the nail and underlying nail bed in several participants confirmed the investigators’ suspicion of a benign tumor abnormality known as an onychopapilloma. The condition causes a colored band (usually white or red) along the length of the nail, along with thickening of the nail underlying the color change and thickening at the end of the nail. It typically only affects one nail.

However, among study participants with known BAP1 tumor predisposition syndrome aged 30 and older, 88% had onychopapilloma tumors affect multiple nails. Researchers suggest that nail screening may be particularly valuable in a patient with a personal or family history of melanoma or other potential BAP1-associated malignancy.

“This finding is rarely seen in the general population, and we believe the presence of nail changes that suggest onychopapillomas on multiple nails should prompt consideration of a diagnosis of BAP1 tumor predisposition syndrome,” said Edward Cowen, M.D, head of Dermatology Consultation Services at NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

“This discovery is an excellent example of how multidisciplinary teams and natural history studies can reveal insights about rare diseases,” said Raffit Hassan, M.D., co-senior author of the study and the Principal Investigator of the clinical protocol in which these patients were enrolled.

More information:
Alexandra Lebensohn et al, Multiple Onychopapillomas and BAP1 Tumor Predisposition Syndrome, JAMA Dermatology (2024). DOI: 10.1001/jamadermatol.2024.1804

Citation:
Benign nail condition linked to rare syndrome that greatly increases cancer risk (2024, May 20)
retrieved 20 May 2024
from https://medicalxpress.com/news/2024-05-benign-condition-linked-rare-syndrome.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2024-05-benign-condition-linked-rare-syndrome.html

Tags: Benignconditionhealth
Previous Post

Researchers discover top-down signals in brain circuits regulating depression

Next Post

Researchers reveal promising treatment target for resistant brain cancer

Sky High Farm’s Biennial Blends Art, Agriculture and Ecological Urgency – observer.com

Sky High Farm’s Biennial Blends Art, Agriculture and Ecological Urgency – observer.com

September 1, 2025

After 150 Job Applications and Rescinded Offers, Computer Science Grads Face an Unforgiving Job Market

September 1, 2025
Proportion of US students taking chemistry fails to keep pace with other science disciplines – Chemistry World

Why Fewer US Students Are Choosing Chemistry Compared to Other Sciences

September 1, 2025
Going zero-waste for a month opened my eyes — here are 7 lessons I wish I knew sooner – VegOut

7 Eye-Opening Lessons I Learned from Living Zero-Waste for a Month

September 1, 2025
This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

September 1, 2025
2 men shot and killed at Don Knabe Community Regional Park in Cerritos – ABC7 Los Angeles

2 men shot and killed at Don Knabe Community Regional Park in Cerritos – ABC7 Los Angeles

September 1, 2025
More drama to come after Australia, USA ignite Women’s Rugby World Cup – ESPN

More drama to come after Australia, USA ignite Women’s Rugby World Cup – ESPN

September 1, 2025
India Was the Economic Alternative to China. Trump Ended That. – The New York Times

How Trump’s Policies Disrupted India’s Bid to Challenge China as an Economic Powerhouse

September 1, 2025
Comanche Nation Entertainment closes casino near Devol – KSWO 7News

Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

September 1, 2025
White House names RFK Jr deputy Jim O’Neill as replacement CDC director – BBC

White House names RFK Jr deputy Jim O’Neill as replacement CDC director – BBC

September 1, 2025

Categories

Archives

September 2025
MTWTFSS
1234567
891011121314
15161718192021
22232425262728
2930 
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (801)
  • Economy (819)
  • Entertainment (21,699)
  • General (16,793)
  • Health (9,860)
  • Lifestyle (834)
  • News (22,149)
  • People (821)
  • Politics (827)
  • Science (16,030)
  • Sports (21,318)
  • Technology (15,800)
  • World (800)

Recent News

Sky High Farm’s Biennial Blends Art, Agriculture and Ecological Urgency – observer.com

Sky High Farm’s Biennial Blends Art, Agriculture and Ecological Urgency – observer.com

September 1, 2025

After 150 Job Applications and Rescinded Offers, Computer Science Grads Face an Unforgiving Job Market

September 1, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version