CHICAGO — Progression-free survival (PFS) was significantly higher with belantamab mafodotin (belamaf; Blenrep) combined with pomalidomide (Pomalyst) and dexamethasone (BPd), compared with standard-of-care pomalidomide, bortezomib (Velcade), and dexamethasone (PVd) in patients with relapsed/refractory multiple myeloma, according to results from the phase III DREAMM-8 trial presented here.
At a median follow-up of 21.8 months, the 12-month estimated PFS rates were 71% with BPd versus 51% with PVd, translating into a 48% reduced risk of disease progression or death with the investigational triplet (HR 0.52, 95% CI 0.37-0.73, P
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