* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Tuesday, October 7, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Charlie Hunnam Reflects on Playing a Serial Killer in Monster: The Ed Gein Story – Yahoo

    Charlie Hunnam Reveals the Dark Challenges of Playing a Serial Killer in Monster: The Ed Gein Story

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    Why Taylor Swift Name-Dropped Elizabeth Taylor in Her New Album – Yahoo

    Here’s Why Taylor Swift Dropped Elizabeth Taylor’s Name in Her New Album

    Al Roker Gives Olivia Dean an Unexpected ‘New Job’ on the ‘Today’ Show – Yahoo

    Al Roker Shocks Olivia Dean with an Exciting New Role on the ‘Today’ Show

    Books about the arts and some haunts for a Denton October – Denton Record-Chronicle

    Uncover Artistic Treasures and Spooky Adventures to Experience in Denton This October

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    ARM Institute opens technology project call to speed submarine manufacturing – The Robot Report

    ARM Institute Unveils Cutting-Edge Technology Project to Revolutionize Submarine Manufacturing

    Forget Cowbells. Cows Wear High-Tech Collars Now. – The New York Times

    Ditch the Cowbells: Discover the High-Tech Collars Transforming Cattle Care

    What the Recent Price Surge Means for Figure Technology Solutions After SEC Settlement – Yahoo Finance

    What the Recent Price Surge Reveals About Figure Technology Solutions Following SEC Settlement

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    Technology Is Becoming More Important Than Humans In CX – No Jitter

    Technology Is Becoming More Important Than Humans In CX – No Jitter

    A Tech Expo Shows What China Can Make, but Not Who’ll Buy It All – The New York Times

    Inside China’s Tech Expo: Cutting-Edge Innovations Face Uncertain Demand

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Charlie Hunnam Reflects on Playing a Serial Killer in Monster: The Ed Gein Story – Yahoo

    Charlie Hunnam Reveals the Dark Challenges of Playing a Serial Killer in Monster: The Ed Gein Story

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    Why Taylor Swift Name-Dropped Elizabeth Taylor in Her New Album – Yahoo

    Here’s Why Taylor Swift Dropped Elizabeth Taylor’s Name in Her New Album

    Al Roker Gives Olivia Dean an Unexpected ‘New Job’ on the ‘Today’ Show – Yahoo

    Al Roker Shocks Olivia Dean with an Exciting New Role on the ‘Today’ Show

    Books about the arts and some haunts for a Denton October – Denton Record-Chronicle

    Uncover Artistic Treasures and Spooky Adventures to Experience in Denton This October

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    ARM Institute opens technology project call to speed submarine manufacturing – The Robot Report

    ARM Institute Unveils Cutting-Edge Technology Project to Revolutionize Submarine Manufacturing

    Forget Cowbells. Cows Wear High-Tech Collars Now. – The New York Times

    Ditch the Cowbells: Discover the High-Tech Collars Transforming Cattle Care

    What the Recent Price Surge Means for Figure Technology Solutions After SEC Settlement – Yahoo Finance

    What the Recent Price Surge Reveals About Figure Technology Solutions Following SEC Settlement

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    Technology Is Becoming More Important Than Humans In CX – No Jitter

    Technology Is Becoming More Important Than Humans In CX – No Jitter

    A Tech Expo Shows What China Can Make, but Not Who’ll Buy It All – The New York Times

    Inside China’s Tech Expo: Cutting-Edge Innovations Face Uncertain Demand

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Efgartigimod efficacious, safe for primary immune thrombocytopenia

October 8, 2023
in Health
Efgartigimod efficacious, safe for primary immune thrombocytopenia
Share on FacebookShare on Twitter

Efgartigimod efficacious, safe for primary immune thrombocytopenia

The first-in-class novel human immunoglobulin G1 Fc fragment, efgartigimod, is efficacious and safe for patients with chronic or persistent primary immune thrombocytopenia, according to a study published online Sept. 28 in The Lancet.

Catherine M. Broome, M.D., from Georgetown University in Washington, D.C., and colleagues conducted a phase 3 24-week study to assess the efficacy and safety of intravenous efgartigimod in adults aged 18 years or older with chronic or persistent primary immune thrombocytopenia who had an average platelet count of less than 30,000, had responded to at least one previous immune thrombocytopenia therapy, and were on or had received at least a second previous immune thrombocytopenia therapy. A total of 131 patients were randomly assigned to efgartigimod or placebo (86 and 45, respectively).

The researchers found that 22 and 5 percent of those receiving efgartigimod and placebo, respectively, reached the primary end point of sustained platelet count response. The median number of weeks of disease control was 2.0 and 0.0 for patients with chronic immune thrombocytopenia receiving efgartigimod and placebo, respectively. Efgartigimod was well tolerated, with adverse events mostly of mild-to-moderate severity. In both groups, the most common adverse events of interest were headache, hematuria, and petechiae.

“The higher proportion of efgartigimod-treated patients with sustained platelet count responses and improved disease control compared with placebo in this population with chronic and persistent disease corroborates and extends the evidence of this novel mechanism for targeting the autoantibody-based pathophysiology of immune thrombocytopenia,” the authors write.

Several authors disclosed ties to biopharmaceutical companies, including argenx, which manufactures efgartigimod and funded the study.

More information:
Catherine M Broome et al, Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial, The Lancet (2023). DOI: 10.1016/S0140-6736(23)01460-5

Syed Mahamad et al, Inhibition of neonatal Fc receptor as a treatment for immune thrombocytopenia, The Lancet (2023). DOI: 10.1016/S0140-6736(23)01836-6

Copyright © 2023 HealthDay. All rights reserved.

Citation:
Efgartigimod efficacious, safe for primary immune thrombocytopenia (2023, October 6)
retrieved 8 October 2023
from https://medicalxpress.com/news/2023-10-efgartigimod-efficacious-safe-primary-immune.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2023-10-efgartigimod-efficacious-safe-primary-immune.html

Tags: efficaciousEfgartigimodhealth
Previous Post

Weight-Loss Drug Benefit Spans HFpEF, HFmrEF

Next Post

Kidney disease gene found to also have a protective mutation

Ecology blazing the trail for more clean energy projects – Washington State Department of Ecology (.gov)

How Ecology is Powering the Shift to a Greener Energy Future

October 7, 2025
Penn State Brandywine Earth sciences professor earns two national awards – Penn State University

Penn State Brandywine Earth sciences professor earns two national awards – Penn State University

October 7, 2025
UNESCO and CODATA launch resources on open science for crisis response – unesco.org

UNESCO and CODATA Launch Innovative Open Science Tools to Enhance Crisis Response

October 7, 2025
New Engen Report Identifies Key Trends and Winning Strategies for Active Lifestyle Brands in 2025 and Beyond – Fitt Insider

New Engen Report Identifies Key Trends and Winning Strategies for Active Lifestyle Brands in 2025 and Beyond – Fitt Insider

October 7, 2025
ARM Institute opens technology project call to speed submarine manufacturing – The Robot Report

ARM Institute Unveils Cutting-Edge Technology Project to Revolutionize Submarine Manufacturing

October 7, 2025
Seahawks’ defensive depth being challenged as injuries stack up – FOX Sports

Seahawks’ defensive depth being challenged as injuries stack up – FOX Sports

October 7, 2025
World Mental Health Day Festival and gala set for this week in NYC – MSNBC News

World Mental Health Day Festival and gala set for this week in NYC – MSNBC News

October 6, 2025
Green economy means jobs for NJ, report says – NJ Spotlight News

Green economy means jobs for NJ, report says – NJ Spotlight News

October 6, 2025
Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

October 6, 2025
Republicans are holding Americans’ health care hostage — and lying about it – MSNBC News

How Republicans Are Holding Americans’ Health Care Hostage – and Deceiving the Public

October 6, 2025

Categories

Archives

October 2025
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (855)
  • Economy (875)
  • Entertainment (21,749)
  • General (17,452)
  • Health (9,917)
  • Lifestyle (888)
  • News (22,149)
  • People (877)
  • Politics (886)
  • Science (16,086)
  • Sports (21,376)
  • Technology (15,856)
  • World (858)

Recent News

Ecology blazing the trail for more clean energy projects – Washington State Department of Ecology (.gov)

How Ecology is Powering the Shift to a Greener Energy Future

October 7, 2025
Penn State Brandywine Earth sciences professor earns two national awards – Penn State University

Penn State Brandywine Earth sciences professor earns two national awards – Penn State University

October 7, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version