* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Saturday, September 6, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    ITV Studios Launches New Entertainment Label – Global Bulletin – IMDb

    ITV Studios Unveils Exciting New Entertainment Label

    TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

    TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

    Jenny Han Dropped a Major ‘The Summer I Turned Pretty’ Easter Egg Revealing [SPOILER] – yahoo.com

    Jenny Han Just Unveiled a Huge ‘The Summer I Turned Pretty’ Easter Egg That Changes Everything [SPOILER]

    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

    Country music star apologizes after drunken show ends with cops taking him down: ‘I’m not OK’ – PennLive.com

    Country Music Star Apologizes After Drunken Show Ends in Police Intervention: ‘I’m Not OK

    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Coherent Joins LLNL’s STARFIRE Diode Technology Working Group to Advance Inertial Fusion Energy – GlobeNewswire

    Coherent Partners with LLNL’s STARFIRE Team to Drive Breakthroughs in Inertial Fusion Energy

    Gene Associated With Deadly Heart Disease in Golden Retrievers Identified – Technology Networks

    Breakthrough Discovery Uncovers Gene Behind Deadly Heart Disease in Golden Retrievers

    Monkey Island LNG Picks ConocoPhillips’ Liquefaction Technology – Hart Energy

    Monkey Island LNG Selects ConocoPhillips’ Advanced Liquefaction Technology for Next-Gen Energy Solutions

    Credo Technology Group Holding Ltd. (CRDO) Surpasses Q1 Earnings and Revenue Estimates – Yahoo Finance

    Credo Technology Group Surpasses Q1 Earnings and Revenue Expectations

    The Economist is hiring a science and technology correspondent – The Economist

    Exciting Opportunity: Become Our Next Science and Technology Correspondent!

    Blockchain lender Figure Technology seeks to raise up to $526M in IPO (FIGR:Pending) – Seeking Alpha

    Blockchain Lender Figure Technology Sets Sights on $526M in Thrilling IPO Launch

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    ITV Studios Launches New Entertainment Label – Global Bulletin – IMDb

    ITV Studios Unveils Exciting New Entertainment Label

    TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

    TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

    Jenny Han Dropped a Major ‘The Summer I Turned Pretty’ Easter Egg Revealing [SPOILER] – yahoo.com

    Jenny Han Just Unveiled a Huge ‘The Summer I Turned Pretty’ Easter Egg That Changes Everything [SPOILER]

    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

    Country music star apologizes after drunken show ends with cops taking him down: ‘I’m not OK’ – PennLive.com

    Country Music Star Apologizes After Drunken Show Ends in Police Intervention: ‘I’m Not OK

    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Coherent Joins LLNL’s STARFIRE Diode Technology Working Group to Advance Inertial Fusion Energy – GlobeNewswire

    Coherent Partners with LLNL’s STARFIRE Team to Drive Breakthroughs in Inertial Fusion Energy

    Gene Associated With Deadly Heart Disease in Golden Retrievers Identified – Technology Networks

    Breakthrough Discovery Uncovers Gene Behind Deadly Heart Disease in Golden Retrievers

    Monkey Island LNG Picks ConocoPhillips’ Liquefaction Technology – Hart Energy

    Monkey Island LNG Selects ConocoPhillips’ Advanced Liquefaction Technology for Next-Gen Energy Solutions

    Credo Technology Group Holding Ltd. (CRDO) Surpasses Q1 Earnings and Revenue Estimates – Yahoo Finance

    Credo Technology Group Surpasses Q1 Earnings and Revenue Expectations

    The Economist is hiring a science and technology correspondent – The Economist

    Exciting Opportunity: Become Our Next Science and Technology Correspondent!

    Blockchain lender Figure Technology seeks to raise up to $526M in IPO (FIGR:Pending) – Seeking Alpha

    Blockchain Lender Figure Technology Sets Sights on $526M in Thrilling IPO Launch

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Experts, Senators Wrestle Over Thorny Drug Shortage Challenge

December 7, 2023
in Health
Experts, Senators Wrestle Over Thorny Drug Shortage Challenge
Share on FacebookShare on Twitter

Experts from industry and academia and lawmakers reached consensus around the dangers and the drivers of drug shortages but clashed over approaches to solving the problem during a Senate Finance Committee hearing on Tuesday.

Drug shortages tend to impact older, low-cost generic medicines. Because of shortages, millions of patients are forced to ration their medications or use a less safe or less effective alternative, explained committee chairman Ron Wyden (D-Ore.).

In an ironic twist given the firestorm over the high cost of prescription drugs, the low cost of generics is part of what’s driving the problem. “You have in effect a ‘race to the bottom’ price war for generics that leads to quality control problems and factory shutdowns, which leads to a shortage of generic drug products that are, of course, in high demand,” Wyden said.

Faulty System Drives Shortages

Inmaculada Hernandez, PharmD, PhD, a pharmacist and professor at the University of California San Diego, explained that regardless of what generic they choose, providers and pharmacies are reimbursed the same amount.

Since they have no incentive to choose a manufacturer with “more resilient and dependable” supply chains, they naturally choose whatever has the lowest acquisition cost, which drives prices down and threatens the sustainability of the market, she said.

Sen. Mike Crapo (R-Idaho), the committee’s ranking member, pointed out prices for generic drugs have dropped “in excess of 50%” since 2016, and the number of manufacturers exiting the generic drug market has eclipsed their rate of entry.

Because of what Crapo described as “razor thin ” profit margins, Hernandez said manufacturers may skimp on factory maintenance or choose to off-shore manufacturing, increasing the risk of quality problems. Quality issues then trigger shortages because manufacturing has to be stopped to address them. And given that these are less profitable drugs, manufacturers enduring such headaches may leave the market entirely, causing market concentration that worsens supply disruptions, Hernandez said.

Made in America?

To fix this broken system, Hernandez said, the federal government could fund the “re-shoring” — returning to the U.S. — of generic manufacturing and link funding to “supply guarantees” and the “resilience” of the supply chain.

She also stressed the need to encourage providers and pharmacies to purchase their drugs from manufacturers who have developed more dependable supply chains.

Sen. Thom Tillis (R-N.C.) also spoke about re-shoring manufacturing. He likened the drug shortage challenge to the supply chain resiliency issues in the semiconductor space. In 2022, Congress passed the CHIPS and Science Act, which provides government funding to boost production of semiconductors in the U.S. Tillis asked whether a similar solution could be used to address drug shortages.

Marta Wosińska, PhD, a health economist and senior fellow at the Brookings Institution in Washington, pointed out that there are roughly 20,000 approved drugs and around 16,000 drug manufacturing facilities, while semiconductor production involves many fewer products and manufacturing sites. But “the framework is good,” she said, citing her written testimony and a proposal she and other colleagues developed that centers around which elements of the supply chain to prioritize.

Manufacturing everything in the U.S. isn’t possible, but the government could think about “friend-shoring” and “near-shoring,” she said. That’s important because if the federal government, for example, moved active pharmaceutical ingredient facilities to the U.S., but upstream manufacturing remained in China, then problems would continue.

Incentivizing Use of Stable Manufacturers

Wosińska also expanded on the idea of incentivizing purchasers to stabilize the drug supply, especially generic sterile injectable (GSI) drug shortages — including “crash cart” drugs, oncology drugs, IV antibiotics, and saline, which she said account for two-thirds of all shortages.

GSI shortages often occur in U.S. sites where the final GSI products are made. To address them, Wosińska argued, the Centers for Medicare & Medicaid Services (CMS) “will need to pay hospitals differently, incentivizing them to consider reliability of supply in their purchasing decisions.”

Under a pay-for-performance program proposed by Wosińska and her colleagues, CMS would retroactively score hospitals against their peers on two measures: whether they buy from reliable manufacturers and whether they “buffer” their inventory. Hospitals would be rewarded for “buying reliably” and “buffering before shortages happen,” she said. Hospitals would not have to determine this reliability themselves; instead, they could lean on group purchasing organizations that already track related measures.

The catch: CMS doesn’t have the authority to set up such a program, particularly if it isn’t budget-neutral, Wosińska said, adding, “This committee, however, can grant that authority.”

Buffering to Prevent Shortages?

The committee also heard from Allan Coukell, BSc (Pharm), a pharmacist and senior vice president of public policy for Civica Rx, of Lehi, Utah, a non-profit drug company founded by health systems and philanthropies specifically to address drug shortages.

Civica Rx works to supply “safe, stable, and affordable” essential medicines by leveraging long-term purchase and supply contracts, keeping a 6-month buffer inventory of every drug, and relying on U.S. sourcing whenever possible. “Twenty of our top 25 products are currently on national shortage, and yet we’re supplying member hospitals without interruption,” Coukell said.

He stressed that incentivizing providers to contract for “buffer inventory” from manufacturers who are less likely to have quality failures can help address shortages, and he called on Congress to create an “insurance policy” at a cost of $4 million per essential drug to ensure “backup domestic manufacturing capacity.”

Coukell also expressed support for a provision — which was eventually dropped — in a draft hospital payment rule that involved CMS paying hospitals more for keeping a “buffer stock” of certain drugs, or contracting with a company to do it for them. Wosińska said she opposed the “buffer inventory idea,” both because she didn’t think it was “enough of an incentive” to drive change, and also because it’s the small hospitals that hurt the most in a shortage.

“What we need to be doing is buffering those that usually get left behind,” Wosińska said.

author['full_name']

Shannon Firth has been reporting on health policy as MedPage Today’s Washington correspondent since 2014. She is also a member of the site’s Enterprise & Investigative Reporting team. Follow

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : MedPageToday – https://www.medpagetoday.com/washington-watch/washington-watch/107710

Tags: Expertshealthsenators
Previous Post

Why Recurrent Infections Can Signal a Major Immune System Issue

Next Post

Tucatinib Regimen Boosts PFS in Advanced HER2-Positive Breast Cancer

Blending art, culture and native plants at Wakamatsu – Mountain Democrat

Discover the Harmony of Art, Culture, and Native Plants at Wakamatsu

September 6, 2025
The Two-Body Problem for Women in Science – Nautilus | Science Connected

The Two-Body Problem for Women in Science – Nautilus | Science Connected

September 6, 2025
How AI and Automation are Speeding Up Science and Discovery – Berkeley Lab News Center (.gov)

How AI and Automation Are Accelerating Breakthroughs in Scientific Discovery

September 6, 2025

American Trust Investment Services Serves as Exclusive Placement Agent in $9 Million Follow-On Offering for Nova LifeStyle, Inc. – Morningstar

September 6, 2025
Coherent Joins LLNL’s STARFIRE Diode Technology Working Group to Advance Inertial Fusion Energy – GlobeNewswire

Coherent Partners with LLNL’s STARFIRE Team to Drive Breakthroughs in Inertial Fusion Energy

September 6, 2025
EA SPORTS™ and New York City FC Extend Partnership to Power the Future of Football Fandom in NYC – New York City FC

EA SPORTS™ and New York City FC Join Forces to Transform Football Fandom in NYC

September 6, 2025
News – Ancient DNA Pinpoints Culprit Responsible for World’s First Pandemic – Archaeology Magazine

Ancient DNA Reveals the True Cause of the World’s First Pandemic

September 5, 2025
Fears of US recession as economy adds just 22,000 jobs – The Times

Fears of US recession as economy adds just 22,000 jobs – The Times

September 5, 2025
Musiq Soulchild Surprises Fan’s Bride With “Dontchange” Wedding Serenade – yahoo.com

Musiq Soulchild Captivates Wedding Guests with Heartfelt Serenade of “Don’tchange

September 5, 2025
States fight feds over future of school mental health services – Courthouse News Service

States Clash with Federal Government Over the Future of School Mental Health Services

September 5, 2025

Categories

Archives

September 2025
MTWTFSS
1234567
891011121314
15161718192021
22232425262728
2930 
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (809)
  • Economy (827)
  • Entertainment (21,704)
  • General (16,879)
  • Health (9,868)
  • Lifestyle (840)
  • News (22,149)
  • People (829)
  • Politics (834)
  • Science (16,038)
  • Sports (21,326)
  • Technology (15,808)
  • World (808)

Recent News

Blending art, culture and native plants at Wakamatsu – Mountain Democrat

Discover the Harmony of Art, Culture, and Native Plants at Wakamatsu

September 6, 2025
The Two-Body Problem for Women in Science – Nautilus | Science Connected

The Two-Body Problem for Women in Science – Nautilus | Science Connected

September 6, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version