* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Thursday, June 26, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Susquehanna Raises Penn Entertainment Inc. (PENN) Price Target. – Yahoo Finance

    Susquehanna Raises Price Target for Penn Entertainment Inc. (PENN)

    George Lopez is coming to Spokane – KXLY.com

    George Lopez is coming to Spokane – KXLY.com

    Netflix unveils Dallas immersive venue for fans of hit shows like ‘Squid Game,’ ‘Stranger Things’ – Houston Chronicle

    Step Inside Netflix’s New Dallas Immersive Experience Featuring Hits Like ‘Squid Game’ and ‘Stranger Things

    ‘Puttin’ on the Ritz’: Civic Players bring ‘Young Frankenstein’ to life – Yahoo

    Civic Players Deliver a Hilarious and Unforgettable Performance of ‘Young Frankenstein

    ‘Wheel of Fortune’: Amputee Wins $60,000 After Breaking Incredible ‘Curse’ – Hastings Tribune

    Wheel of Fortune’ Amputee Breaks Incredible ‘Curse’ to Win $60,000!

    North Star Sports & Entertainment Network: Coming soon – KTTC News

    North Star Sports & Entertainment Network: Coming soon – KTTC News

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Frontdoor Announces Tech Expert Dr. Bala Ganesh as Chief Technology Officer – Business Wire

    Frontdoor Appoints Tech Visionary Dr. Bala Ganesh as New Chief Technology Officer

    Defense technology giant Northrop Grumman to host interviews in Iuka to fill technician roles – supertalk.fm

    Defense technology giant Northrop Grumman to host interviews in Iuka to fill technician roles – supertalk.fm

    China’s Military Introduces Mosquito-Sized Drones: A Game-Changing Surveillance Technology – Indian Defence Review

    China Unveils Mosquito-Sized Drones: Revolutionizing Surveillance Technology

    Marvell Technology Stock Rallies After AI Event Sparks Investor Optimism – Yahoo Finance

    Marvell Technology Stock Rallies After AI Event Sparks Investor Optimism – Yahoo Finance

    Promising Technology Stocks To Follow Today – June 22nd – MarketBeat

    Top Technology Stocks to Watch Today – June 22nd

    Technology Convergence Report 2025 – The World Economic Forum

    Technology Convergence Report 2025 – The World Economic Forum

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Susquehanna Raises Penn Entertainment Inc. (PENN) Price Target. – Yahoo Finance

    Susquehanna Raises Price Target for Penn Entertainment Inc. (PENN)

    George Lopez is coming to Spokane – KXLY.com

    George Lopez is coming to Spokane – KXLY.com

    Netflix unveils Dallas immersive venue for fans of hit shows like ‘Squid Game,’ ‘Stranger Things’ – Houston Chronicle

    Step Inside Netflix’s New Dallas Immersive Experience Featuring Hits Like ‘Squid Game’ and ‘Stranger Things

    ‘Puttin’ on the Ritz’: Civic Players bring ‘Young Frankenstein’ to life – Yahoo

    Civic Players Deliver a Hilarious and Unforgettable Performance of ‘Young Frankenstein

    ‘Wheel of Fortune’: Amputee Wins $60,000 After Breaking Incredible ‘Curse’ – Hastings Tribune

    Wheel of Fortune’ Amputee Breaks Incredible ‘Curse’ to Win $60,000!

    North Star Sports & Entertainment Network: Coming soon – KTTC News

    North Star Sports & Entertainment Network: Coming soon – KTTC News

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Frontdoor Announces Tech Expert Dr. Bala Ganesh as Chief Technology Officer – Business Wire

    Frontdoor Appoints Tech Visionary Dr. Bala Ganesh as New Chief Technology Officer

    Defense technology giant Northrop Grumman to host interviews in Iuka to fill technician roles – supertalk.fm

    Defense technology giant Northrop Grumman to host interviews in Iuka to fill technician roles – supertalk.fm

    China’s Military Introduces Mosquito-Sized Drones: A Game-Changing Surveillance Technology – Indian Defence Review

    China Unveils Mosquito-Sized Drones: Revolutionizing Surveillance Technology

    Marvell Technology Stock Rallies After AI Event Sparks Investor Optimism – Yahoo Finance

    Marvell Technology Stock Rallies After AI Event Sparks Investor Optimism – Yahoo Finance

    Promising Technology Stocks To Follow Today – June 22nd – MarketBeat

    Top Technology Stocks to Watch Today – June 22nd

    Technology Convergence Report 2025 – The World Economic Forum

    Technology Convergence Report 2025 – The World Economic Forum

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

New study used 3D-printed sensors to measure spinal cord malformations in embryos

July 13, 2024
in Health
New study used 3D-printed sensors to measure spinal cord malformations in embryos
Share on FacebookShare on Twitter

New ways to study spinal cord malformations in embryos

The i3D bioprinting with accurately determined position, geometry and stiffness. Credit: Nature Materials (2024). DOI: 10.1038/s41563-024-01942-9

A group of scientists at UCL have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.

The study, published in Nature Materials and in collaboration with the University of Padua and the Veneto Institute of Molecular Medicine (VIMM), uses innovative biotechnologies to measure the mechanical forces exerted by the embryo during its development.

These forces are crucial in the formation of organs and anatomical systems, such as the formation of the neural tube, which gives rise to the central nervous system.

Congenital spinal cord malformations affect around one in 2,000 newborns in Europe each year.

Although these malformations have been studied for decades, they cannot be fully explained through molecular and genetic studies alone.

As a result, researchers are now looking at the physical and mechanical forces in tissues during embryo development. However, this can be challenging as the embryonic spinal cord is tiny—too small to be seen with the naked eye—and extremely delicate. Force measuring devices therefore need to be similarly small and soft to avoid disrupting normal growth.

To overcome these difficulties, researchers 3D printed tiny force sensors (about 0.1mm wide) directly inside the developing nervous system of chicken embryos.

These force sensors begin as a liquid applied directly to the developing embryos. When exposed to a strong laser, the liquid transforms into a spring-like solid. This solid attaches to the growing spinal cord of the embryos and gets deformed by the mechanical forces produced by the embryo’s cells.

This enabled them to measure the minute forces—about a tenth of the weight of a human eyelash—that embryos must generate to form the spinal cord.

New ways to study spinal cord malformations in embryos

“V” spring force sensors. Credit: Nature Materials (2024). DOI: 10.1038/s41563-024-01942-9

For normal embryonic development, these forces must be greater than the opposing negative forces.

Quantifying the forces would allow researchers to explore drugs capable of sufficiently increasing positive forces or decreasing negative ones, in order to help prevent congenital malformations such as spina bifida.

Such drugs could also complement the benefits of folic acid intake—a well-established strategy for preventing developmental problems before and during pregnancy.

Lead author, Marie Sklowdowska Curie postdoctoral fellow, Dr. Eirini Maniou (UCL Great Ormond Street Institute of Child Health and University of Padua), said, “Thanks to the use of novel biomaterials and advanced microscopy, this study promises a step change in the field of embryonic mechanics and lays the foundation for a unified understanding of development.

“Our work paves the way for identifying new preventative and therapeutic strategies for central nervous system malformations.”

The research group also demonstrated that the same technology could be applied to human stem cells, as they develop into spinal cord cells.

In the future, this would allow for comparisons between the stem cells of healthy donors and patients with spina bifida, with the goal of understanding why some people develop the condition.

Co-senior author, Dr. Gabriel Galea (UCL Great Ormond Street Institute of Child Health), said, “This technology is very versatile and widely applicable to many research fields, and we hope it will be quickly adopted and applied by other groups to address fundamental questions.”

Co-senior author, Professor Nicola Elvassore (University of Padua and VIMM), added, “This discovery not only allows us to better understand the mechanical forces at play during embryonic development but also offers new perspectives for intervening and preventing conditions like spina bifida.

“The ability to quantify embryonic forces with such precision represents a significant step forward in biomedical research.”

More information:
Eirini Maniou et al, Quantifying mechanical forces during vertebrate morphogenesis, Nature Materials (2024). DOI: 10.1038/s41563-024-01942-9

Citation:
New study used 3D-printed sensors to measure spinal cord malformations in embryos (2024, July 12)
retrieved 13 July 2024
from https://medicalxpress.com/news/2024-07-3d-sensors-spinal-cord-malformations.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2024-07-3d-sensors-spinal-cord-malformations.html

Tags: D-Printedhealthstudy
Previous Post

Q&A: Finding novel therapies for childhood cancer

Next Post

Unraveling disease patterns in older adults starting long-term care in Japan and their future health outcomes

Tiny night lizards survived dinosaur-killing asteroid strike, despite being close enough to see it happen – Live Science

How Tiny Night Lizards Miraculously Survived the Dinosaur-Killing Asteroid Impact

June 26, 2025
Scientists Confirm Anti-Aging Drug Appears to Prolong Life in Animals – ScienceAlert

Scientists Confirm Anti-Aging Drug Appears to Prolong Life in Animals – ScienceAlert

June 26, 2025
Tokyo Lifestyle Makes Strategic Move into Australian Market with Premium Store in Sydney Chinatown – Stock Titan

Tokyo Lifestyle Makes Strategic Move into Australian Market with Premium Store in Sydney Chinatown – Stock Titan

June 26, 2025
First images from world’s largest digital camera reveal galaxies and cosmic collisions – NBC News

First images from world’s largest digital camera reveal galaxies and cosmic collisions – NBC News

June 26, 2025
Spirit Airlines Rebrands Travel Options: First, Premium Economy, Value – One Mile at a Time

Spirit Airlines Unveils Exciting New Travel Options: First, Premium Economy, and Value Classes

June 26, 2025
Susquehanna Raises Penn Entertainment Inc. (PENN) Price Target. – Yahoo Finance

Susquehanna Raises Price Target for Penn Entertainment Inc. (PENN)

June 26, 2025

Vanderburgh County Health Department Takes Bold Action Against Vaccine Hesitancy

June 26, 2025
Why Trump needs the world to believe Iran’s nuclear program is ‘obliterated’ – CNN

Why Trump Wants the World to Believe Iran’s Nuclear Program Is Completely Destroyed

June 26, 2025
House panel wrangles on rail safety technology – FreightWaves

House Panel Sparks Debate Over the Future of Rail Safety Technology

June 26, 2025
The Desert Sun unveils its Top Spring Athletes: History-makers and record-breakers – The Desert Sun

Meet This Spring’s Top Athletes: History-Makers and Record-Breakers Revealed!

June 26, 2025

Categories

Archives

June 2025
MTWTFSS
 1
2345678
9101112131415
16171819202122
23242526272829
30 
« May    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (698)
  • Economy (718)
  • Entertainment (21,613)
  • General (15,574)
  • Health (9,757)
  • Lifestyle (723)
  • News (22,149)
  • People (720)
  • Politics (725)
  • Science (15,936)
  • Sports (21,214)
  • Technology (15,702)
  • World (698)

Recent News

Tiny night lizards survived dinosaur-killing asteroid strike, despite being close enough to see it happen – Live Science

How Tiny Night Lizards Miraculously Survived the Dinosaur-Killing Asteroid Impact

June 26, 2025
Scientists Confirm Anti-Aging Drug Appears to Prolong Life in Animals – ScienceAlert

Scientists Confirm Anti-Aging Drug Appears to Prolong Life in Animals – ScienceAlert

June 26, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version