* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Tuesday, July 22, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    AP Entertainment SummaryBrief at 1:51 p.m. EDT – Channel 3000

    Entertainment Highlights: Key Updates You Can’t Miss

    ‘Devil Wears Prada 2’ casts Anne Hathaway’s love interest replacing Adrian Grenier’s Nate – Entertainment Weekly

    Devil Wears Prada 2′ Casts New Love Interest for Anne Hathaway, Replacing Adrian Grenier’s Nate

    12 ‘Late Show’ Moments Proving Stephen Colbert Can’t Be Replaced – The Mountaineer

    12 Unforgettable ‘Late Show’ Moments That Prove Stephen Colbert Is Truly One of a Kind

    Canes owner Tom Dundon’s real estate firm eyes entertainment complex near RDU – The Business Journals

    Canes Owner Tom Dundon’s Real Estate Firm Unveils Plans for Thrilling New Entertainment Complex Near RDU

    Inspired Entertainment, Inc.’s (NASDAQ:INSE) Price Is Right But Growth Is Lacking After Shares Rocket 29% – simplywall.st

    Inspired Entertainment Soars 29% but Growth Momentum Falls Short

    Kroger shares summer entertainment tips – Supermarket Perimeter

    Ultimate Summer Entertainment Tips to Make Your Season Unforgettable

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Transformative technology, support for food entrepreneurs spotlighted – University of Hawaii System

    How Cutting-Edge Technology and Strong Support Are Revolutionizing Food Entrepreneurs’ Success

    Cold Weather Alloy Opens New Possibilities for Space Technology – Universe Today

    Revolutionary Cold Weather Alloy Unlocks New Frontiers in Space Technology

    Defence Holdings PLC Transitions from Esports to Pioneering Defence Technology

    Bull of the Day: Credo Technology Group (CRDO) – Yahoo Finance

    Bull of the Day: Why Credo Technology Group (CRDO) Is Poised for a Breakout

    BlackSky Technology Inc. Stock Analysis and Forecast – Explosive wealth accumulation – Jammu Links News

    BlackSky Technology Inc.: Unlocking Explosive Wealth Potential Through Expert Stock Analysis and Forecast

    Polypurine Hairpin Technology is Safe, Effective at Inhibiting PCSK9 to Regulate Cholesterol – Pharmacy Times

    Polypurine Hairpin Technology: A Safe and Powerful Breakthrough for Controlling Cholesterol by Targeting PCSK9

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    AP Entertainment SummaryBrief at 1:51 p.m. EDT – Channel 3000

    Entertainment Highlights: Key Updates You Can’t Miss

    ‘Devil Wears Prada 2’ casts Anne Hathaway’s love interest replacing Adrian Grenier’s Nate – Entertainment Weekly

    Devil Wears Prada 2′ Casts New Love Interest for Anne Hathaway, Replacing Adrian Grenier’s Nate

    12 ‘Late Show’ Moments Proving Stephen Colbert Can’t Be Replaced – The Mountaineer

    12 Unforgettable ‘Late Show’ Moments That Prove Stephen Colbert Is Truly One of a Kind

    Canes owner Tom Dundon’s real estate firm eyes entertainment complex near RDU – The Business Journals

    Canes Owner Tom Dundon’s Real Estate Firm Unveils Plans for Thrilling New Entertainment Complex Near RDU

    Inspired Entertainment, Inc.’s (NASDAQ:INSE) Price Is Right But Growth Is Lacking After Shares Rocket 29% – simplywall.st

    Inspired Entertainment Soars 29% but Growth Momentum Falls Short

    Kroger shares summer entertainment tips – Supermarket Perimeter

    Ultimate Summer Entertainment Tips to Make Your Season Unforgettable

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Transformative technology, support for food entrepreneurs spotlighted – University of Hawaii System

    How Cutting-Edge Technology and Strong Support Are Revolutionizing Food Entrepreneurs’ Success

    Cold Weather Alloy Opens New Possibilities for Space Technology – Universe Today

    Revolutionary Cold Weather Alloy Unlocks New Frontiers in Space Technology

    Defence Holdings PLC Transitions from Esports to Pioneering Defence Technology

    Bull of the Day: Credo Technology Group (CRDO) – Yahoo Finance

    Bull of the Day: Why Credo Technology Group (CRDO) Is Poised for a Breakout

    BlackSky Technology Inc. Stock Analysis and Forecast – Explosive wealth accumulation – Jammu Links News

    BlackSky Technology Inc.: Unlocking Explosive Wealth Potential Through Expert Stock Analysis and Forecast

    Polypurine Hairpin Technology is Safe, Effective at Inhibiting PCSK9 to Regulate Cholesterol – Pharmacy Times

    Polypurine Hairpin Technology: A Safe and Powerful Breakthrough for Controlling Cholesterol by Targeting PCSK9

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

New study used 3D-printed sensors to measure spinal cord malformations in embryos

July 13, 2024
in Health
New study used 3D-printed sensors to measure spinal cord malformations in embryos
Share on FacebookShare on Twitter

New ways to study spinal cord malformations in embryos

The i3D bioprinting with accurately determined position, geometry and stiffness. Credit: Nature Materials (2024). DOI: 10.1038/s41563-024-01942-9

A group of scientists at UCL have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.

The study, published in Nature Materials and in collaboration with the University of Padua and the Veneto Institute of Molecular Medicine (VIMM), uses innovative biotechnologies to measure the mechanical forces exerted by the embryo during its development.

These forces are crucial in the formation of organs and anatomical systems, such as the formation of the neural tube, which gives rise to the central nervous system.

Congenital spinal cord malformations affect around one in 2,000 newborns in Europe each year.

Although these malformations have been studied for decades, they cannot be fully explained through molecular and genetic studies alone.

As a result, researchers are now looking at the physical and mechanical forces in tissues during embryo development. However, this can be challenging as the embryonic spinal cord is tiny—too small to be seen with the naked eye—and extremely delicate. Force measuring devices therefore need to be similarly small and soft to avoid disrupting normal growth.

To overcome these difficulties, researchers 3D printed tiny force sensors (about 0.1mm wide) directly inside the developing nervous system of chicken embryos.

These force sensors begin as a liquid applied directly to the developing embryos. When exposed to a strong laser, the liquid transforms into a spring-like solid. This solid attaches to the growing spinal cord of the embryos and gets deformed by the mechanical forces produced by the embryo’s cells.

This enabled them to measure the minute forces—about a tenth of the weight of a human eyelash—that embryos must generate to form the spinal cord.

New ways to study spinal cord malformations in embryos

“V” spring force sensors. Credit: Nature Materials (2024). DOI: 10.1038/s41563-024-01942-9

For normal embryonic development, these forces must be greater than the opposing negative forces.

Quantifying the forces would allow researchers to explore drugs capable of sufficiently increasing positive forces or decreasing negative ones, in order to help prevent congenital malformations such as spina bifida.

Such drugs could also complement the benefits of folic acid intake—a well-established strategy for preventing developmental problems before and during pregnancy.

Lead author, Marie Sklowdowska Curie postdoctoral fellow, Dr. Eirini Maniou (UCL Great Ormond Street Institute of Child Health and University of Padua), said, “Thanks to the use of novel biomaterials and advanced microscopy, this study promises a step change in the field of embryonic mechanics and lays the foundation for a unified understanding of development.

“Our work paves the way for identifying new preventative and therapeutic strategies for central nervous system malformations.”

The research group also demonstrated that the same technology could be applied to human stem cells, as they develop into spinal cord cells.

In the future, this would allow for comparisons between the stem cells of healthy donors and patients with spina bifida, with the goal of understanding why some people develop the condition.

Co-senior author, Dr. Gabriel Galea (UCL Great Ormond Street Institute of Child Health), said, “This technology is very versatile and widely applicable to many research fields, and we hope it will be quickly adopted and applied by other groups to address fundamental questions.”

Co-senior author, Professor Nicola Elvassore (University of Padua and VIMM), added, “This discovery not only allows us to better understand the mechanical forces at play during embryonic development but also offers new perspectives for intervening and preventing conditions like spina bifida.

“The ability to quantify embryonic forces with such precision represents a significant step forward in biomedical research.”

More information:
Eirini Maniou et al, Quantifying mechanical forces during vertebrate morphogenesis, Nature Materials (2024). DOI: 10.1038/s41563-024-01942-9

Citation:
New study used 3D-printed sensors to measure spinal cord malformations in embryos (2024, July 12)
retrieved 13 July 2024
from https://medicalxpress.com/news/2024-07-3d-sensors-spinal-cord-malformations.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2024-07-3d-sensors-spinal-cord-malformations.html

Tags: D-Printedhealthstudy
Previous Post

Q&A: Finding novel therapies for childhood cancer

Next Post

Unraveling disease patterns in older adults starting long-term care in Japan and their future health outcomes

Lifestyle startup Escape Plan raises $5 million to launch over 100 offline stores across India – Indian Startup News

Lifestyle Startup Escape Plan Secures $5 Million to Open 100+ Offline Stores Across India

July 22, 2025
Kauffman Foundation launches new executive role to lead its Real World Learning team – Startland News

Kauffman Foundation Creates Exciting New Executive Role to Drive Real World Learning Initiatives

July 22, 2025
Economic Planning Shouldn’t Be a Swear Word – Jacobin

Why It’s Time to Give Economic Planning Another Shot

July 22, 2025
AP Entertainment SummaryBrief at 1:51 p.m. EDT – Channel 3000

Entertainment Highlights: Key Updates You Can’t Miss

July 22, 2025
Department of Labor changes home health care, migrant farm worker rules – WBUR

Department of Labor changes home health care, migrant farm worker rules – WBUR

July 22, 2025
Band’s set nixed over ‘politics and propaganda’ concerns in Luzerne County – WNEP

Band’s set nixed over ‘politics and propaganda’ concerns in Luzerne County – WNEP

July 22, 2025
Transformative technology, support for food entrepreneurs spotlighted – University of Hawaii System

How Cutting-Edge Technology and Strong Support Are Revolutionizing Food Entrepreneurs’ Success

July 22, 2025
Saturday is for the buzz? Fox Sports inks TV deal with Barstool Sports, Dave Portnoy – The New York Times

Saturday is for the buzz? Fox Sports inks TV deal with Barstool Sports, Dave Portnoy – The New York Times

July 22, 2025
Zegna Plants Roots in Aspen with Ambition to Expand Conservation Initiatives Globally – The Impression

Zegna Plants Roots in Aspen with Ambition to Expand Conservation Initiatives Globally – The Impression

July 22, 2025
EPA targets science research office – The Hill

EPA targets science research office – The Hill

July 22, 2025

Categories

Archives

July 2025
MTWTFSS
 123456
78910111213
14151617181920
21222324252627
28293031 
« Jun    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (733)
  • Economy (757)
  • Entertainment (21,641)
  • General (16,042)
  • Health (9,795)
  • Lifestyle (765)
  • News (22,149)
  • People (758)
  • Politics (766)
  • Science (15,973)
  • Sports (21,254)
  • Technology (15,739)
  • World (740)

Recent News

Lifestyle startup Escape Plan raises $5 million to launch over 100 offline stores across India – Indian Startup News

Lifestyle Startup Escape Plan Secures $5 Million to Open 100+ Offline Stores Across India

July 22, 2025
Kauffman Foundation launches new executive role to lead its Real World Learning team – Startland News

Kauffman Foundation Creates Exciting New Executive Role to Drive Real World Learning Initiatives

July 22, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version