* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Saturday, August 23, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

    From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

    How to watch ‘F1: The Movie’ on Prime Video – About Amazon

    Experience the Thrill: How to Stream ‘F1: The Movie’ on Prime Video

    FOX One is now available on Prime Video: Here’s everything to know – About Amazon

    FOX One is now available on Prime Video: Here’s everything to know – About Amazon

    What Are Our Predictions for Taylor Swift’s ‘Life of a Showgirl’ Based on What She’s Told Us So Far? – yahoo.com

    Uncover the Hidden Surprises in Taylor Swift’s ‘Life of a Showgirl’ – Can You Decode Her Clues?

    Bama Dining Serving Up New Food, Entertainment – UA News Center

    Bama Dining Launches Thrilling New Food and Entertainment Experiences

    The latest on Williams-Brice Stadium renovations, entertainment district – On3

    Discover the Thrilling New Upgrades Coming to Williams-Brice Stadium and Its Vibrant Entertainment District!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Alcorn State awarded grant to boost STEM with VR technology – WJTV

    Alcorn State Secures Grant to Transform STEM Education Through Cutting-Edge VR Technology

    Hyundai: The Only Way To Beat China Is To Embrace Technology – InsideEVs

    Hyundai’s Bold Strategy to Outpace China with Cutting-Edge Technology

    Teaching older adults how to use technology – WWNY

    Empowering Older Adults to Master Technology with Confidence

    Denver man receives pacemaker using new technology – CBS News

    Denver Man’s Life Transformed by Revolutionary Pacemaker Technology

    Morgan County Rescue Squad is using new technology to recover people missing in the water faster – WAFF

    Morgan County Rescue Squad is using new technology to recover people missing in the water faster – WAFF

    YSU to celebrate launch of new radiology technology program – WKBN.com

    YSU Launches Exciting New Radiology Technology Program Celebration

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

    From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

    How to watch ‘F1: The Movie’ on Prime Video – About Amazon

    Experience the Thrill: How to Stream ‘F1: The Movie’ on Prime Video

    FOX One is now available on Prime Video: Here’s everything to know – About Amazon

    FOX One is now available on Prime Video: Here’s everything to know – About Amazon

    What Are Our Predictions for Taylor Swift’s ‘Life of a Showgirl’ Based on What She’s Told Us So Far? – yahoo.com

    Uncover the Hidden Surprises in Taylor Swift’s ‘Life of a Showgirl’ – Can You Decode Her Clues?

    Bama Dining Serving Up New Food, Entertainment – UA News Center

    Bama Dining Launches Thrilling New Food and Entertainment Experiences

    The latest on Williams-Brice Stadium renovations, entertainment district – On3

    Discover the Thrilling New Upgrades Coming to Williams-Brice Stadium and Its Vibrant Entertainment District!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Alcorn State awarded grant to boost STEM with VR technology – WJTV

    Alcorn State Secures Grant to Transform STEM Education Through Cutting-Edge VR Technology

    Hyundai: The Only Way To Beat China Is To Embrace Technology – InsideEVs

    Hyundai’s Bold Strategy to Outpace China with Cutting-Edge Technology

    Teaching older adults how to use technology – WWNY

    Empowering Older Adults to Master Technology with Confidence

    Denver man receives pacemaker using new technology – CBS News

    Denver Man’s Life Transformed by Revolutionary Pacemaker Technology

    Morgan County Rescue Squad is using new technology to recover people missing in the water faster – WAFF

    Morgan County Rescue Squad is using new technology to recover people missing in the water faster – WAFF

    YSU to celebrate launch of new radiology technology program – WKBN.com

    YSU Launches Exciting New Radiology Technology Program Celebration

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Pretherapy imaging and dosimetry offer personalized treatment planning for thyroid cancer patients

June 22, 2023
in Health
Pretherapy imaging and dosimetry offer personalized treatment planning for thyroid cancer patients
Share on FacebookShare on Twitter

Pretherapy imaging and dosimetry offer personalized treatment planning for thyroid cancer patients

Example of whole-body planar scans at 24 hours after 123I-NaI administration at baseline, before selumetinib was administered (A), and after 4 weeks of treatment with selumetinib (B). Credit: Society of Nuclear Medicine

A combination of pretherapy imaging and dosimetry can help ensure that patients with refractory differentiated thyroid cancer obtain the maximum benefit from radioactive iodine treatments following redifferentiation therapy. In this novel approach, a small amount of radioactive iodine was used to determine whether the treatment was being delivered to the thyroid lesions.

If the treatment was absorbed well, researchers from The Royal Marsden NHS Foundation Trust were able to calculate a personalized dosage of treatment for each patient. Results from this multicenter phase II trial, led by the UK NCRI Thyroid Cancer Research Group, were published in the June issue of the Journal of Nuclear Medicine.

Differentiated thyroid cancer has been treated with radioactive iodine for over 80 years. While the majority of patients respond well to initial treatment, in some cases further administration is needed. After several treatments, 5% to 10% of patients no longer take up the iodine. This carries a poor prognosis with a median overall survival of three to five years.

“The drug selumetinib has shown potential to restore or enhance the uptake of radioactive iodine treatment in patients,” said Jan Taprogge, Ph.D., principal clinical scientist at The Royal Marsden NHS Foundation Trust. “In this study we aimed to investigate whether selumetinib could resensitize these differentiated thyroid cancer patients to radioiodine.”

Patients with iodine refractory disease (one or more lesions with no measurable iodine uptake or an iodine-avid lesion that progressed within 12 months of radioactive iodine treatments) were included in the study. Participants underwent baseline 123I-NaI SPECT/CT and then received selumetinib orally twice daily for four weeks. Follow-up 123I-NaI SPECT/CT imaging was used to determine if an increase in 123I-NaI was observed after taking selumetinib. In patients who did see an increase, therapy was warranted. Pre-therapy and post-therapy dosimetry were performed and the range of absorbed doses was calculated.

A wide variation in the radiation delivered to different areas of disease was found among patients. However, researchers noted that this variability can be accurately predicted from scans taken just before the therapy with just a small amount of the radioactive drug.

“It is likely that the response to treatment is largely dependent on how much of the injected radiation is delivered to the disease as absorbed dose, and the range of radiation doses delivered may partly explain the variation in outcomes. The ability to predict the radiation doses delivered to areas of disease implies that this could be considered when planning treatment and that treatments may be tailored to individual patients,” stated Taprogge.

The authors noted that the methods developed for this study—in particular the close collaboration between medical centers to collect and share images and radiation dosimetry results—open the door to more informed treatments that could improve outcomes. These methods can be applied to the wider field of molecular radiotherapy and could significantly improve the clinical and cost effectiveness of existing and new radiotherapeutics.

More information:
Jan Taprogge et al, The Role of Pretherapy Quantitative Imaging and Dosimetry in Radioiodine Therapy for Advanced Thyroid Cancer, Journal of Nuclear Medicine (2023). DOI: 10.2967/jnumed.122.264913

Citation:
Pretherapy imaging and dosimetry offer personalized treatment planning for thyroid cancer patients (2023, June 22)
retrieved 22 June 2023
from https://medicalxpress.com/news/2023-06-pretherapy-imaging-dosimetry-personalized-treatment.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2023-06-pretherapy-imaging-dosimetry-personalized-treatment.html

Tags: healthimagingPretherapy
Previous Post

Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

Next Post

A Breath of Fresh Air: Purifiers for Spaces Post-Pandemic

Putin wants to attend 2026 FIFA World Cup in the U.S. “very badly,” Trump says – Axios

Putin Eager to Attend 2026 FIFA World Cup in the U.S., Says Trump

August 23, 2025
How the semiconductor boom and ASU are transforming Arizona’s economy – ASU News

How the semiconductor boom and ASU are transforming Arizona’s economy – ASU News

August 23, 2025
From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

From polka to Poison, Corn Palace adjusts entertainment offerings with the times – Mitchell Republic

August 23, 2025
Luther College to host discussion exploring links between soil and food health – Luther College

Luther College to host discussion exploring links between soil and food health – Luther College

August 23, 2025
OPINION | WOODY BASSETT: Can the nation do better in its politics? Can the Democrats? – Northwest Arkansas Democrat-Gazette

OPINION | WOODY BASSETT: Can the nation do better in its politics? Can the Democrats? – Northwest Arkansas Democrat-Gazette

August 23, 2025
Crossings: How Road Ecology is Shaping the Future of Our Planet – Living on Earth

Crossings: How Road Ecology is Shaping the Future of Our Planet

August 23, 2025
Toyota Friday Night Rivals kicks off season with Elizabethton at Science Hill – WCYB

Toyota Friday Night Rivals Ignite the Season with Elizabethton vs. Science Hill Showdown

August 23, 2025
Star Trek as Refuge for the Science-Minded – The Provincetown Independent

How Star Trek Ignites Passion and Empowers the Science-Minded

August 23, 2025
Refresh your wardrobe at these 11 QTS award-winning fashion and lifestyle stores – Time Out Worldwide

Transform Your Look with These 11 Must-Visit Fashion and Lifestyle Stores

August 23, 2025
Alcorn State awarded grant to boost STEM with VR technology – WJTV

Alcorn State Secures Grant to Transform STEM Education Through Cutting-Edge VR Technology

August 23, 2025

Categories

Archives

August 2025
MTWTFSS
 123
45678910
11121314151617
18192021222324
25262728293031
« Jul    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (785)
  • Economy (806)
  • Entertainment (21,685)
  • General (16,624)
  • Health (9,846)
  • Lifestyle (818)
  • News (22,149)
  • People (807)
  • Politics (815)
  • Science (16,018)
  • Sports (21,304)
  • Technology (15,786)
  • World (787)

Recent News

Putin wants to attend 2026 FIFA World Cup in the U.S. “very badly,” Trump says – Axios

Putin Eager to Attend 2026 FIFA World Cup in the U.S., Says Trump

August 23, 2025
How the semiconductor boom and ASU are transforming Arizona’s economy – ASU News

How the semiconductor boom and ASU are transforming Arizona’s economy – ASU News

August 23, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version