* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Monday, October 27, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Dylan Efron suffers brutal nose injury in ‘DWTS’ rehearsals – Yahoo

    Dylan Efron Endures Painful Nose Injury During ‘DWTS’ Rehearsals

    Person shot, injured in parking lot of adult entertainment club in Gresham – KPTV

    Person Shot and Injured in Gresham Adult Entertainment Club Parking Lot

    Meet Belynda From ‘Married at First Sight’ Season 19: Age, Job, Instagram and More – Yahoo

    Meet Belynda from ‘Married at First Sight’ Season 19: Age, Career, Instagram & More Revealed!

    General Hospital’s Rena Sofer Exits as Lois — But the Door Isn’t Closed – Yahoo

    General Hospital’s Rena Sofer Exits as Lois — But the Door Isn’t Closed – Yahoo

    CNN Launches New Show – What to Know About Host Elex Michaelson – Central Oregon Daily

    Get to Know Elex Michaelson: The Dynamic New Host Taking CNN by Storm

    Johnny Depp Set To Finally Make His Big Hollywood Comeback After Amber Heard Controversy – Yahoo

    Johnny Depp Set for a Triumphant Hollywood Comeback Following Amber Heard Controversy

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Researchers Discover New Bacterium That Turns Food Waste Into Energy – Technology Networks

    Scientists Unveil Breakthrough Bacterium That Transforms Food Waste Into Clean Energy

    Jim Cramer on GSI Technology: “That Thing is a Rocket Ship” – Yahoo Finance

    Jim Cramer Labels GSI Technology a “Rocket Ship” Poised for Takeoff

    The Anti-Tech Backlash Is Going to Grow Stronger – Jacobin

    The Anti-Tech Backlash Is Gaining Unstoppable Momentum

    Comments to EU Regarding the Draft Revised Technology Transfer Block Exemption Regulation and Technology Transfer Guidelines – Information Technology and Innovation Foundation

    Have Your Say: Share Your Thoughts on the Draft Revised Technology Transfer Block Exemption Regulation and Guidelines

    Ghost Tapping is exploiting tap-to-pay technology in order to steal your money; what your need to know – ABC7 New York

    Ghost Tapping: How Thieves Are Using Tap-to-Pay Technology to Steal Your Money and What You Need to Know

    New technology for grading and packing dates – FreshPlaza

    Revolutionary Technology Transforms Date Grading and Packing Process

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Dylan Efron suffers brutal nose injury in ‘DWTS’ rehearsals – Yahoo

    Dylan Efron Endures Painful Nose Injury During ‘DWTS’ Rehearsals

    Person shot, injured in parking lot of adult entertainment club in Gresham – KPTV

    Person Shot and Injured in Gresham Adult Entertainment Club Parking Lot

    Meet Belynda From ‘Married at First Sight’ Season 19: Age, Job, Instagram and More – Yahoo

    Meet Belynda from ‘Married at First Sight’ Season 19: Age, Career, Instagram & More Revealed!

    General Hospital’s Rena Sofer Exits as Lois — But the Door Isn’t Closed – Yahoo

    General Hospital’s Rena Sofer Exits as Lois — But the Door Isn’t Closed – Yahoo

    CNN Launches New Show – What to Know About Host Elex Michaelson – Central Oregon Daily

    Get to Know Elex Michaelson: The Dynamic New Host Taking CNN by Storm

    Johnny Depp Set To Finally Make His Big Hollywood Comeback After Amber Heard Controversy – Yahoo

    Johnny Depp Set for a Triumphant Hollywood Comeback Following Amber Heard Controversy

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Researchers Discover New Bacterium That Turns Food Waste Into Energy – Technology Networks

    Scientists Unveil Breakthrough Bacterium That Transforms Food Waste Into Clean Energy

    Jim Cramer on GSI Technology: “That Thing is a Rocket Ship” – Yahoo Finance

    Jim Cramer Labels GSI Technology a “Rocket Ship” Poised for Takeoff

    The Anti-Tech Backlash Is Going to Grow Stronger – Jacobin

    The Anti-Tech Backlash Is Gaining Unstoppable Momentum

    Comments to EU Regarding the Draft Revised Technology Transfer Block Exemption Regulation and Technology Transfer Guidelines – Information Technology and Innovation Foundation

    Have Your Say: Share Your Thoughts on the Draft Revised Technology Transfer Block Exemption Regulation and Guidelines

    Ghost Tapping is exploiting tap-to-pay technology in order to steal your money; what your need to know – ABC7 New York

    Ghost Tapping: How Thieves Are Using Tap-to-Pay Technology to Steal Your Money and What You Need to Know

    New technology for grading and packing dates – FreshPlaza

    Revolutionary Technology Transforms Date Grading and Packing Process

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Psoriatic Arthritis Treatment Failure Tied to Key Factors

July 24, 2024
in Health
Psoriatic Arthritis Treatment Failure Tied to Key Factors
Share on FacebookShare on Twitter

TOPLINE:

Failure to respond to targeted disease-modifying antirheumatic drugs (tsDMARDs) for psoriatic arthritis occurs at an incident rate of about 0.35 per person-year.

METHODOLOGY:

An observational cohort of 591 individuals at the University of Toronto, Toronto, Ontario, Canada, with psoriatic arthritis (mean age, 48.2 years) who started advanced therapy between 2000 and 2023 was followed prospectively.Primary failure was defined as inefficacy during treatment or failure to meet response criteria (≥ 40% reduction in swollen joint count and ≥ 50% reduction in Psoriasis Area and Severity Index scores) after 1 year.The researchers grouped patients into responders, treatment failures, and individuals who discontinued therapy for other reasons.

TAKEAWAY:

Therapies involved tumor necrosis factor (TNF) inhibitors (82.2%), etanercept (39.3%), IL-17 inhibitors (8.3%), IL-23 or IL-12/IL-23 inhibitors (4.4%), and tsDMARDs (4.4%).Treatment response occurred in 49.9% of participants, treatment failure in 35.4%, and therapy stoppage for other reasons in 14.7%. Treatment failure rates were 32.5% for TNF inhibitors, 50.7% for non-TNF inhibitor biologics, and 43.3% for tsDMARDs.Greater risk for primary failure was linked to daily alcohol consumption (odds ratio [OR], 3.52; 95% CI, 1.33-9.31), higher body mass index (OR, 1.04; 95% CI, 1.01-1.08), and fibromyalgia (OR, 2.07; 95% CI, 1.03-4.16).Higher educational level (OR, 0.51; 95% CI, 0.38-0.87), higher damaged joint count (OR, 0.95; 95% CI, 0.93-0.99), and HLA-B27 positivity (OR, 0.40; 95% CI, 0.17, 0.97) conferred lower risk for primary failure. 

IN PRACTICE:

“We always try to look for clinical profiling of patients to know how a patient will respond to therapy. This helps in that,” said presenting author Fadi Kharouf, MD, a clinical fellow at Toronto Western Hospital, Toronto, in an interview.

SOURCE:

Dr Kharouf and coauthors presented the study as a poster at the GRAPPA 2024 annual meeting.

LIMITATIONS:

The study was a retrospective analysis and cannot demonstrate causality. The study was conducted at a single center in Canada, which may limit generalizability.

DISCLOSURES:

The study received funding from the Krembil Foundation.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medscape – https://www.medscape.com/viewarticle/factors-associated-treatment-failure-psoriatic-arthritis-2024a1000djo

Tags: ArthritishealthPsoriatic
Previous Post

Are GLP-1s Bad for Retinas?

Next Post

This app shows how the MacBook’s ugly notch can be pretty useful

The Bearded Vulture as an accumulator of historical remains: Insights for future ecological and biocultural studies – ESA Journals

The Bearded Vulture: Unlocking Secrets of Historical Remains for Future Ecological and Biocultural Research

October 27, 2025
«The subdued earth»: the history of thinking about science and faith. – omnesmag.com

The Subdued Earth: Unraveling the Intricate Relationship Between Science and Faith

October 27, 2025
Scientists Just Took a Big Step Toward Letting Humans Breathe Through Their Butts – Men’s Health

Scientists Make Breakthrough That Could Let Humans Breathe Through Their Butts

October 27, 2025
Costco Finally Brought This International Bakery Item to the U.S. – Yahoo

Costco Finally Brings Beloved International Bakery Treat to the U.S.!

October 27, 2025
Researchers Discover New Bacterium That Turns Food Waste Into Energy – Technology Networks

Scientists Unveil Breakthrough Bacterium That Transforms Food Waste Into Clean Energy

October 27, 2025
15 games, four leagues, plenty of props: How bettors view the sports equinox – ESPN

15 Games, 4 Leagues, and a World of Betting Props: Dive Into the Ultimate Sports Equinox

October 27, 2025
Canada-U.S. Tensions Stay on Baseball Field During Blue Jays-Dodgers World Series – The New York Times

Canada-U.S. Rivalry Heats Up on the Baseball Field in Blue Jays-Dodgers World Series

October 27, 2025
Marketplace without a storefront: how ChatGPT is creating a new shopping economy in the age of AI – realnoevremya.com

How ChatGPT is Transforming Shopping with a Storefront-Free Marketplace in the AI Era

October 27, 2025
Dylan Efron suffers brutal nose injury in ‘DWTS’ rehearsals – Yahoo

Dylan Efron Endures Painful Nose Injury During ‘DWTS’ Rehearsals

October 27, 2025
Close Up: The future of health care premiums, open races in 2026 – KCCI

What’s Next for Health Care Premiums and the High-Stakes 2026 Elections?

October 27, 2025

Categories

Archives

October 2025
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (888)
  • Economy (910)
  • Entertainment (21,781)
  • General (17,834)
  • Health (9,951)
  • Lifestyle (923)
  • News (22,149)
  • People (911)
  • Politics (920)
  • Science (16,121)
  • Sports (21,410)
  • Technology (15,890)
  • World (893)

Recent News

The Bearded Vulture as an accumulator of historical remains: Insights for future ecological and biocultural studies – ESA Journals

The Bearded Vulture: Unlocking Secrets of Historical Remains for Future Ecological and Biocultural Research

October 27, 2025
«The subdued earth»: the history of thinking about science and faith. – omnesmag.com

The Subdued Earth: Unraveling the Intricate Relationship Between Science and Faith

October 27, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version