* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Thursday, September 4, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    ITV Studios Launches New Entertainment Label – Global Bulletin – IMDb

    ITV Studios Unveils Exciting New Entertainment Label

    TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

    TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

    Jenny Han Dropped a Major ‘The Summer I Turned Pretty’ Easter Egg Revealing [SPOILER] – yahoo.com

    Jenny Han Just Unveiled a Huge ‘The Summer I Turned Pretty’ Easter Egg That Changes Everything [SPOILER]

    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

    Country music star apologizes after drunken show ends with cops taking him down: ‘I’m not OK’ – PennLive.com

    Country Music Star Apologizes After Drunken Show Ends in Police Intervention: ‘I’m Not OK

    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Credo Technology Group Holding Ltd. (CRDO) Surpasses Q1 Earnings and Revenue Estimates – Yahoo Finance

    Credo Technology Group Surpasses Q1 Earnings and Revenue Expectations

    The Economist is hiring a science and technology correspondent – The Economist

    Exciting Opportunity: Become Our Next Science and Technology Correspondent!

    Blockchain lender Figure Technology seeks to raise up to $526M in IPO (FIGR:Pending) – Seeking Alpha

    Blockchain Lender Figure Technology Sets Sights on $526M in Thrilling IPO Launch

    New Technology from Ramsey Theory Group Brings Diagnostic Testing and Telehealth Directly into Patients’ Homes – Yahoo Finance

    Revolutionary Ramsey Theory Technology Delivers Diagnostic Testing and Telehealth Right to Your Doorstep

    China’s CATL sells stake in Finnish subcontract car manufacturer – Reuters

    China’s CATL Sells Stake in Finnish Auto Supplier in Strategic Move

    This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

    How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    ITV Studios Launches New Entertainment Label – Global Bulletin – IMDb

    ITV Studios Unveils Exciting New Entertainment Label

    TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

    TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

    Jenny Han Dropped a Major ‘The Summer I Turned Pretty’ Easter Egg Revealing [SPOILER] – yahoo.com

    Jenny Han Just Unveiled a Huge ‘The Summer I Turned Pretty’ Easter Egg That Changes Everything [SPOILER]

    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

    Country music star apologizes after drunken show ends with cops taking him down: ‘I’m not OK’ – PennLive.com

    Country Music Star Apologizes After Drunken Show Ends in Police Intervention: ‘I’m Not OK

    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Credo Technology Group Holding Ltd. (CRDO) Surpasses Q1 Earnings and Revenue Estimates – Yahoo Finance

    Credo Technology Group Surpasses Q1 Earnings and Revenue Expectations

    The Economist is hiring a science and technology correspondent – The Economist

    Exciting Opportunity: Become Our Next Science and Technology Correspondent!

    Blockchain lender Figure Technology seeks to raise up to $526M in IPO (FIGR:Pending) – Seeking Alpha

    Blockchain Lender Figure Technology Sets Sights on $526M in Thrilling IPO Launch

    New Technology from Ramsey Theory Group Brings Diagnostic Testing and Telehealth Directly into Patients’ Homes – Yahoo Finance

    Revolutionary Ramsey Theory Technology Delivers Diagnostic Testing and Telehealth Right to Your Doorstep

    China’s CATL sells stake in Finnish subcontract car manufacturer – Reuters

    China’s CATL Sells Stake in Finnish Auto Supplier in Strategic Move

    This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

    How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Shortened antibiotic treatment for ventilator-associated pneumonia in ICU patients just as effective as standard course

January 26, 2024
in Health
Shortened antibiotic treatment for ventilator-associated pneumonia in ICU patients just as effective as standard course
Share on FacebookShare on Twitter

ventilator

Credit: Unsplash/CC0 Public Domain

Less is also better—that is what researchers have found while conducting a tri-nation clinical trial to see if shorter courses of antibiotics are as effective as longer prescriptions of the drug to treat ventilator-associated pneumonia.

The research is published in The Lancet Respiratory Medicine journal.

The four-year long REducing Antibiotic tReatment Duration for Ventilator-Associated Pneumonia (REGARD-VAP) study involved 460 patients in 39 hospital intensive care units in Nepal, Thailand and Singapore. While personalized short-course treatment duration for patients with ventilator-associated pneumonia (VAP) was just as effective in reducing the duration of pneumonia in comparison to the standard treatment duration, the short-course treatment strategy also successfully reduced antibiotic side effects from 38% to 8%.

VAP is a common lung infection among critically ill patients in hospital intensive care units, who are dependent on ventilators to breathe. It occurs when bacteria invade the lower respiratory tract and thin lung tissues via the breathing tube. The infection leads to longer hospital stays, increased antibiotic use, and the risk of death is as much as 40%. The study’s findings serve as a point of reference for antibiotic usage reduction and titration, so that the onset of antibiotic resistance can be prevented.

The study’s author and infectious diseases physician Dr. Mo Yin from the Infectious Diseases Translational Research Programme at the Yong Loo Lin School of Medicine (NUS Medicine) and Consultant from the Division of Infectious Diseases in the Department of Medicine at National University Hospital (NUH) said, “Antibiotics are the default treatment used for patients with ventilator-associated pneumonia, which is the commonest hospital-acquired infection in the intensive care units.

“However, antibiotics when used in indiscriminately in large amounts will make antibiotics less effective over time and increase bacteria’s resistance to antibiotics. This clinical study shows that the duration and the strategy of antibiotic treatment can be tailored based on how the patient responds to treatment and is feasible enough to be adopted even in settings with limited resources, coupled with constant evaluation by attending physicians.”

The 460 patients with VAP were randomly assigned into two groups—a three-to-five day individualized, short-course antibiotic treatment plan, and a longer, standard-of-course treatment plan of a minimum eight days. The main aim was to determine if the individualized short-course strategy is non-inferior to the usual standard-of-care duration, in terms of the increased risk of death or the recurrence of pneumonia happening within 60 days of enrolling into the study. Of the 460 participants, 41% in the individualized short-course group and 44% in the standard-of-care group either died or had pneumonia recurrence.

Participants were reviewed daily to assess if they met the criteria to stop antibiotics; the criteria included a core body temperature of less than or equal to 38.3 degrees Celsius for 48 hours and stable blood pressure. When the criteria were met, all participants in the short-course treatment strategy group were weaned off antibiotics after three to five days of receiving VAP treatment.

For patients in the standard care duration group, the antibiotic treatment strategy lasted at least eight days, as determined by their primary physicians. Current standard-of-care antibiotic treatment can last up to two to three weeks, accompanied by higher risks of side effects and unnecessary economic costs.

More information:
Yin Mo et al, Individualised, short-course antibiotic treatment versus usual long-course treatment for ventilator-associated pneumonia (REGARD-VAP): a multicentre, individually randomised, open-label, non-inferiority trial, The Lancet Respiratory Medicine (2024). DOI: 10.1016/S2213-2600(23)00418-6

Citation:
Shortened antibiotic treatment for ventilator-associated pneumonia in ICU patients just as effective as standard course (2024, January 26)
retrieved 26 January 2024
from https://medicalxpress.com/news/2024-01-shortened-antibiotic-treatment-ventilator-pneumonia.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2024-01-shortened-antibiotic-treatment-ventilator-pneumonia.html

Tags: AntibiotichealthShortened
Previous Post

Female reproductive milestones may be risk factors for diabetes and high cholesterol later in life

Next Post

What are the symptoms of an enlarged prostate and how is it treated?

Potential caterpillar mimicry in a tropical hummingbird – Falk – 2025 – Ecology – ESA Journals

Tropical Hummingbird’s Surprising Caterpillar Mimicry Revealed

September 4, 2025
Degrees of Science: Healthy Aging – KWTX

Unlocking the Secrets to Healthy Aging: A Science-Based Guide

September 4, 2025
Podcast: Blame, bad drivers, and ‘safety science’ – BikePortland

Podcast: Blame, bad drivers, and ‘safety science’ – BikePortland

September 4, 2025
If you want your 60s to be some of the best years of your life, say goodbye to these 5 behaviors – VegOut

If you want your 60s to be some of the best years of your life, say goodbye to these 5 behaviors – VegOut

September 4, 2025
Credo Technology Group Holding Ltd. (CRDO) Surpasses Q1 Earnings and Revenue Estimates – Yahoo Finance

Credo Technology Group Surpasses Q1 Earnings and Revenue Expectations

September 4, 2025

NFL Week 1 Power Rankings: Eagles Take Early Lead, But Bills Poised to Claim Ultimate Crown

September 4, 2025
Xi Parades Military Strength as Trump Accuses Him of Conspiring With Putin and Kim – The New York Times

Xi Unveils Military Strength as Trump Levels Accusations of Alliances with Putin and Kim

September 4, 2025
Trump tariffs and the Fed: Fate of U.S. economy may lie with the Supreme Court – Axios

How the Supreme Court Could Decide the Future of the U.S. Economy Amid Trump Tariffs and Fed Moves

September 4, 2025
ITV Studios Launches New Entertainment Label – Global Bulletin – IMDb

ITV Studios Unveils Exciting New Entertainment Label

September 4, 2025
RFK Jr. is spreading a reckless myth about SSRIs and mass shootings – MSNBC News

RFK Jr. Fuels Dangerous Myth Linking SSRIs to Mass Shootings

September 4, 2025

Categories

Archives

September 2025
MTWTFSS
1234567
891011121314
15161718192021
22232425262728
2930 
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (806)
  • Economy (824)
  • Entertainment (21,704)
  • General (16,848)
  • Health (9,865)
  • Lifestyle (839)
  • News (22,149)
  • People (826)
  • Politics (831)
  • Science (16,035)
  • Sports (21,323)
  • Technology (15,805)
  • World (805)

Recent News

Potential caterpillar mimicry in a tropical hummingbird – Falk – 2025 – Ecology – ESA Journals

Tropical Hummingbird’s Surprising Caterpillar Mimicry Revealed

September 4, 2025
Degrees of Science: Healthy Aging – KWTX

Unlocking the Secrets to Healthy Aging: A Science-Based Guide

September 4, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version