* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Wednesday, September 3, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

    TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

    Jenny Han Dropped a Major ‘The Summer I Turned Pretty’ Easter Egg Revealing [SPOILER] – yahoo.com

    Jenny Han Just Unveiled a Huge ‘The Summer I Turned Pretty’ Easter Egg That Changes Everything [SPOILER]

    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

    Country music star apologizes after drunken show ends with cops taking him down: ‘I’m not OK’ – PennLive.com

    Country Music Star Apologizes After Drunken Show Ends in Police Intervention: ‘I’m Not OK

    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

    Erykah Badu Announces ‘Abi & Alan’ Album With The Alchemist Will Be Delayed – yahoo.com

    Erykah Badu Opens Up About the Delay of Her Highly Anticipated ‘Abi & Alan’ Album with The Alchemist

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Blockchain lender Figure Technology seeks to raise up to $526M in IPO (FIGR:Pending) – Seeking Alpha

    Blockchain Lender Figure Technology Sets Sights on $526M in Thrilling IPO Launch

    New Technology from Ramsey Theory Group Brings Diagnostic Testing and Telehealth Directly into Patients’ Homes – Yahoo Finance

    Revolutionary Ramsey Theory Technology Delivers Diagnostic Testing and Telehealth Right to Your Doorstep

    China’s CATL sells stake in Finnish subcontract car manufacturer – Reuters

    China’s CATL Sells Stake in Finnish Auto Supplier in Strategic Move

    This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

    How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

    Gator football kicks off with excitement and new technology – WCJB | TV20

    Gator Football Kicks Off with Thrilling Action and Innovative Technology

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

    TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

    Jenny Han Dropped a Major ‘The Summer I Turned Pretty’ Easter Egg Revealing [SPOILER] – yahoo.com

    Jenny Han Just Unveiled a Huge ‘The Summer I Turned Pretty’ Easter Egg That Changes Everything [SPOILER]

    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

    Country music star apologizes after drunken show ends with cops taking him down: ‘I’m not OK’ – PennLive.com

    Country Music Star Apologizes After Drunken Show Ends in Police Intervention: ‘I’m Not OK

    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

    Erykah Badu Announces ‘Abi & Alan’ Album With The Alchemist Will Be Delayed – yahoo.com

    Erykah Badu Opens Up About the Delay of Her Highly Anticipated ‘Abi & Alan’ Album with The Alchemist

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Blockchain lender Figure Technology seeks to raise up to $526M in IPO (FIGR:Pending) – Seeking Alpha

    Blockchain Lender Figure Technology Sets Sights on $526M in Thrilling IPO Launch

    New Technology from Ramsey Theory Group Brings Diagnostic Testing and Telehealth Directly into Patients’ Homes – Yahoo Finance

    Revolutionary Ramsey Theory Technology Delivers Diagnostic Testing and Telehealth Right to Your Doorstep

    China’s CATL sells stake in Finnish subcontract car manufacturer – Reuters

    China’s CATL Sells Stake in Finnish Auto Supplier in Strategic Move

    This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

    How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

    Gator football kicks off with excitement and new technology – WCJB | TV20

    Gator Football Kicks Off with Thrilling Action and Innovative Technology

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Testing PD-1 Inhibition With Neoadjuvant Anti-HER2 Therapy in Breast Cancer

July 4, 2023
in Health
Testing PD-1 Inhibition With Neoadjuvant Anti-HER2 Therapy in Breast Cancer
Share on FacebookShare on Twitter

At the American Society of Clinical Oncology (ASCO) annual meeting, researchers reported on a multicenter, phase II trial exploring the efficacy and safety of adding pembrolizumab (Keytruda) to the standard-of-care treatment of paclitaxel (Taxol), trastuzumab (Herceptin), and pertuzumab (Perjeta; THP) in chemotherapy-naive patients with invasive, HER2-positive breast cancer.

In this exclusive MedPage Today video, Jin Sun L. Bitar, MD, a breast oncologist from Cedars Sinai Medical Center in Los Angeles, explained the study background and design.

Following is a transcript of her remarks:

The neoHIP trial is a prospective, multicenter trial for HER2-positive early-stage breast cancer. So the trial was designed to test adding immune checkpoint inhibitor pembrolizumab to the standard-of-care HER2-targeted and chemo-based neoadjuvant regimen.

So the study was opened [in] 2018 with the study arms. So arm A we call THP, so that’s paclitaxel, trastuzumab, and pertuzumab. And then arm B is that arm A plus pembrolizumab, so with the immune checkpoint inhibitor. And arm C is paclitaxel with trastuzumab. But after our pre-analysis, we closed arm C.

So we have two arms, arm A and arm B. Our goal is 58 patients in each arm. So far I think we enrolled a little bit more than 30 patients in each arm. So the primary endpoint is pCR [pathologic complete response]. We are expecting the report soon.

There were a lot of clinical trials [testing] the immune checkpoint inhibitor for the advanced setting in HER2-positive disease, but it didn’t really show good efficacy. So I think we need to use that immune checkpoint more in the early setting. So like now the neoadjuvant trial we have, because the chemotherapy actually changes the immune microenvironment, the tumor. So if wait until end of lines, then it wouldn’t work. So that’s why we wanted to bring this immunotherapy in the early setting. So hopefully we can decrease the chemo toxicity by adding immune checkpoint inhibitor.

author['full_name']

Greg Laub is the Senior Director of Video and currently leads the video and podcast production teams. Follow

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : MedPageToday – https://www.medpagetoday.com/meetingcoverage/ascovideopearlsmetastaticbreastca/105294

Tags: healthInhibitiontesting
Previous Post

Employer says talks stalled in B.C. port workers strike

Next Post

New Data on BCMA-Directed Bispecifics in Multiple Myeloma

TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

September 3, 2025
How Trump health conspiracy theories went wild on social media – CNN

The Wild Spread of Trump Health Conspiracy Theories on Social Media

September 3, 2025
Inside the Democratic plan to recapture the House majority in 2026 – The Washington Post

Democrats’ Bold Strategy to Win Back the House Majority in 2026

September 3, 2025
Grassland ecological compensation accounting based on the flow of emergy ecological products: a case from the Qinghai Tibet region, China – Nature

Innovative Grassland Ecological Compensation Accounting Using Emergy Flow: Insights from the Qinghai-Tibet Region

September 3, 2025
Climate scientists file a public, point-by-point rebuttal of Trump admin report casting doubt on climate change – CNN

Climate Scientists Deliver a Detailed Public Rebuttal to Trump Administration’s Climate Change Doubts

September 3, 2025
Earth’s Seasons Are Out of Sync, Scientists Discover From Space – ScienceAlert

Scientists Reveal Earth’s Seasons Are Falling Out of Sync Through Space Observations

September 3, 2025
Fasting glucose improvement following a short-term, culturally adapted lifestyle intervention in Latino adults at risk for type 2 diabetes mellitus: a quasi-experimental study – BMC Nutrition

Short-Term Culturally Tailored Lifestyle Intervention Boosts Fasting Glucose in Latino Adults at Risk for Type 2 Diabetes

September 3, 2025
Blockchain lender Figure Technology seeks to raise up to $526M in IPO (FIGR:Pending) – Seeking Alpha

Blockchain Lender Figure Technology Sets Sights on $526M in Thrilling IPO Launch

September 3, 2025
One big question for every postseason team, Rangers in the mix & notable September call-ups – Yahoo Sports

Key Questions for Every Postseason Team: Rangers in the Mix and Notable September Call-Ups

September 3, 2025
Is it OK to be happy when the world is falling apart? | Avram Alpert – The Guardian

Is It Possible to Find True Happiness When the World Feels Like It’s Falling Apart?

September 3, 2025

Categories

Archives

September 2025
MTWTFSS
1234567
891011121314
15161718192021
22232425262728
2930 
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (804)
  • Economy (822)
  • Entertainment (21,703)
  • General (16,829)
  • Health (9,864)
  • Lifestyle (837)
  • News (22,149)
  • People (824)
  • Politics (831)
  • Science (16,033)
  • Sports (21,321)
  • Technology (15,803)
  • World (803)

Recent News

TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

September 3, 2025
How Trump health conspiracy theories went wild on social media – CNN

The Wild Spread of Trump Health Conspiracy Theories on Social Media

September 3, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version