* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Thursday, October 30, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Rock Hall Ceremony Adds Chappell, Donald Glover – Yahoo

    Chappell and Donald Glover Shine Bright in a Star-Studded Rock Hall Celebration

    Caesars Entertainment (CZR) Reports Q3 Loss, Lags Revenue Estimates – Yahoo Finance

    Caesars Entertainment Stumbles in Q3, Falls Short of Revenue Goals

    Free Live Entertainment – Fremont Street Experience

    Enjoy Free Live Entertainment on Fremont Street Tonight!

    What to Know About ‘Good Morning America’s 50th Anniversary Episode – Wyoming News Now

    Celebrate the Milestone: Everything You Need to Know About Good Morning America’s 50th Anniversary Episode

    Dylan Efron suffers brutal nose injury in ‘DWTS’ rehearsals – Yahoo

    Dylan Efron Endures Painful Nose Injury During ‘DWTS’ Rehearsals

    Person shot, injured in parking lot of adult entertainment club in Gresham – KPTV

    Person Shot and Injured in Gresham Adult Entertainment Club Parking Lot

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Chipmaker Nvidia hits $5 trillion valuation – Al Jazeera

    Nvidia Rockets to an Astonishing $5 Trillion Valuation

    How digital technologies can support a circular economy – Tech Xplore

    Unlocking the Power of Digital Technologies to Fuel a Thriving Circular Economy

    Nigeria’s government is using digital technology to repress citizens. A researcher explains how – The Conversation

    Nigeria’s government is using digital technology to repress citizens. A researcher explains how – The Conversation

    CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

    CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

    Researchers Discover New Bacterium That Turns Food Waste Into Energy – Technology Networks

    Scientists Unveil Breakthrough Bacterium That Transforms Food Waste Into Clean Energy

    Jim Cramer on GSI Technology: “That Thing is a Rocket Ship” – Yahoo Finance

    Jim Cramer Labels GSI Technology a “Rocket Ship” Poised for Takeoff

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Rock Hall Ceremony Adds Chappell, Donald Glover – Yahoo

    Chappell and Donald Glover Shine Bright in a Star-Studded Rock Hall Celebration

    Caesars Entertainment (CZR) Reports Q3 Loss, Lags Revenue Estimates – Yahoo Finance

    Caesars Entertainment Stumbles in Q3, Falls Short of Revenue Goals

    Free Live Entertainment – Fremont Street Experience

    Enjoy Free Live Entertainment on Fremont Street Tonight!

    What to Know About ‘Good Morning America’s 50th Anniversary Episode – Wyoming News Now

    Celebrate the Milestone: Everything You Need to Know About Good Morning America’s 50th Anniversary Episode

    Dylan Efron suffers brutal nose injury in ‘DWTS’ rehearsals – Yahoo

    Dylan Efron Endures Painful Nose Injury During ‘DWTS’ Rehearsals

    Person shot, injured in parking lot of adult entertainment club in Gresham – KPTV

    Person Shot and Injured in Gresham Adult Entertainment Club Parking Lot

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Chipmaker Nvidia hits $5 trillion valuation – Al Jazeera

    Nvidia Rockets to an Astonishing $5 Trillion Valuation

    How digital technologies can support a circular economy – Tech Xplore

    Unlocking the Power of Digital Technologies to Fuel a Thriving Circular Economy

    Nigeria’s government is using digital technology to repress citizens. A researcher explains how – The Conversation

    Nigeria’s government is using digital technology to repress citizens. A researcher explains how – The Conversation

    CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

    CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

    Researchers Discover New Bacterium That Turns Food Waste Into Energy – Technology Networks

    Scientists Unveil Breakthrough Bacterium That Transforms Food Waste Into Clean Energy

    Jim Cramer on GSI Technology: “That Thing is a Rocket Ship” – Yahoo Finance

    Jim Cramer Labels GSI Technology a “Rocket Ship” Poised for Takeoff

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Troponin Could Play Larger Role Predicting Risk in Stable CAD

July 31, 2023
in Health
Troponin Could Play Larger Role Predicting Risk in Stable CAD
Share on FacebookShare on Twitter

Already established for the assessment of people with suspected acute coronary syndrome (ACS), cardiac troponin also predicted coronary events in people with symptoms suggestive of stable angina, the MICA group showed.

Sampled just before diagnostic outpatient angiography, high-sensitivity cardiac troponin I (hs-cTnI) results tracked with the presence of angiographically proven coronary artery disease (CAD) and subsequent myocardial infarction (MI) or cardiovascular death:

No CAD: troponin 1.9 ng/LCAD with no event: 3.3 ng/LCAD with an event: 6.7 ng/L

Troponin concentrations were associated with the primary outcome after adjusting for cardiovascular risk factors and CAD severity (adjusted HR 2.3, 95% CI 1.7-3.0), reported Nicholas Mills, MD, PhD, of University of Edinburgh and the Royal Infirmary of Edinburgh in Scotland.

Moreover, troponin>10 ng/L was the threshold that identified patients with a 50% increase in the risk of MI or cardiovascular death over a median follow-up of 2.4 years, the authors showed in the Journal of the American College of Cardiology.

“Together these findings suggest that routine cardiac troponin testing could provide important additional information to guide the management of patients with chronic CAD,” they wrote, noting that the role of troponin testing in diagnosing chronic disease itself is “likely to be limited.”

It is possible that routine testing could inform the selection of high-risk patients for treatment intensification, such revascularization or a short period of dual antiplatelet therapy, Mill’s group suggested. “Randomized trials are needed to evaluate whether routine cardiac troponin testing to guide the management of patients with chronic CAD can reduce major adverse cardiovascular events.”

For now, routine troponin testing is not recommended for people with chronic CAD despite studies showing its prognostic value in some people with asymptomatic heart disease or heart attack survivors.

Recently updated American recommendations give a class I endorsement for revascularization to improve symptoms in patients with lifestyle-limiting angina despite guideline-directed medical therapy and with coronary stenoses amenable to revascularization.

“Current risk stratification strategies for patients with chronic CAD primarily focus on the identification of obstructive disease and revascularization targets using anatomical and functional imaging. However, one-half of all MIs occur in patients with nonobstructive coronary disease who typically do not have the ischemic substrate on functional testing to effectively guide risk stratification,” Mills and colleagues argued.

In their report, angiography revealed CAD in 92% of the symptomatic cohort: 32% with nonobstructive disease and 68% with obstructive disease.

“The role of cTn continues to evolve beyond ACS, with emerging data such as in MICA supporting its application as a risk-stratification tool in patients with CCS [chronic coronary syndrome]. Although more data are needed to understand how to use this prognostic information to improve outcomes, the measurement of hs-cTn in patients with chronic CAD may serve multiple functions,” agreed Yader Sandoval, MD, of Minneapolis Heart Institute, Abbott Northwestern Hospital, and Allan Jaffe, MD, of Mayo Clinic in Rochester, Minnesota.

“Recognizing that increasing severity of angina is associated with worse outcomes because of more adverse anatomy, it may be that hs-cTn is beneficial in higher-risk patients with more symptoms rather than in those with mild or no symptoms,” they noted in an accompanying editorial.

For the study, the MICA investigators had prospectively enrolled a cohort of consecutive patients with suspected stable angina who were scheduled for outpatient coronary angiography from 2016 to 2021. They had hs-cTnI measured, but their clinicians were blinded to the results so as not to alter the course of subsequent clinical care.

Participants were 4,240 individuals averaging age 66, with one in three being women. Most were already on lipid-lowering and antiplatelet therapy.

Ultimately, 6% had primary outcome events over follow-up.

This study cohort may not represent the full spectrum of chronic CAD, the investigators cautioned. They added that external validation of the results is needed in other settings, and that they did not evaluate changes in cardiac troponin over time.

author['full_name']

Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow

Disclosures

The study was funded by a grant from the British Heart Foundation and supported by DataLoch, which is funded by the Data Driven Innovation programme within the Edinburgh and South East Scotland City Region Deal.

Mills was supported by awards from the British Heart Foundation and has received honoraria from Abbott Diagnostics, Siemens Healthineers, Roche Diagnostics, and LumiraDx; and institutional research grants from Abbott Diagnostics and Siemens Healthineers.

Sandoval has been on advisory boards for Abbott Diagnostics, Roche Diagnostics, Philips, and Zoll; and holds patent 20210401347 (for machine learning models for ECG-based troponin assessment) along with others.

Jaffe has consulted for Abbott, Roche, Siemens, Beckman-Coulter, Ortho, Radiometer, Astellas, SpinChip, LumiraDx, and RCE Technologies; and holds patent 20210401347 along with others.

Primary Source

Journal of the American College of Cardiology

Source Reference: Wereski R, et al “High-sensitivity cardiac troponin for risk assessment in patients with chronic coronary artery disease” J Am Coll Cardiol 2023; DOI: 10.1016/j.jacc.2023.05.046.

Secondary Source

Journal of the American College of Cardiology

Source Reference: Sandoval Y and Jaffe AS “The evolving role of cardiac troponin: from acute to chronic coronary syndromes” J Am Coll Cardiol 2023; DOI: 10.1016/j.jacc.2023.05.047

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : MedPageToday – https://www.medpagetoday.com/cardiology/prevention/105700

Tags: CouldhealthTroponin
Previous Post

Banks report tighter lending standards, weaker demand for mortgages and HELOCs

Next Post

CMS Announces New Dementia Care Model for Medicare Patients

National TRAP Program targets ghostly issue with second round of coastal clean up funding – EurekAlert!

National TRAP Program Launches Second Wave of Funding to Combat Ghost Gear on Our Coasts

October 29, 2025
In the Presence of the Minister of Energy, Cisco and King Abdullah University of Science and Technology (KAUST) launch landmark AI Institute to accelerate AI research, development, and talent in Saudi Arabia – Cisco Newsroom

Cisco and KAUST Launch Revolutionary AI Institute to Drive Saudi Arabia’s Innovation and Talent Growth

October 29, 2025
Whitman’s DIVAS Program Builds Computational Thinking Skills in Future Scientists – Whitman College

Whitman’s DIVAS Program Ignites Future Scientists with Vital Computational Thinking Skills

October 29, 2025
Reynolds Wrap unveils a Dubai Chocolate turkey recipe – Yahoo

Discover the Irresistible Dubai Chocolate Turkey Recipe

October 29, 2025
Chipmaker Nvidia hits $5 trillion valuation – Al Jazeera

Nvidia Rockets to an Astonishing $5 Trillion Valuation

October 29, 2025
High school sports roundup for Oct. 27-28, 2025 – My Edmonds News

High school sports roundup for Oct. 27-28, 2025 – My Edmonds News

October 29, 2025
Dodgers win WS classic on Freeman’s HR in 18th – ESPN

Dodgers Clinch Epic 18-Inning World Series Victory with Freeman’s Walk-Off Home Run

October 29, 2025
Which indicators are the most accurate in determining the state of the economy? – WOSU Public Media

The Key Economic Indicators That Truly Reveal Our Economy’s Health

October 29, 2025
Rock Hall Ceremony Adds Chappell, Donald Glover – Yahoo

Chappell and Donald Glover Shine Bright in a Star-Studded Rock Hall Celebration

October 29, 2025
Project THRIVE expected to have positive impact on area teens’ mental health – theflintcouriernews.com

Project THRIVE Launches to Empower and Support Local Teens’ Mental Health

October 29, 2025

Categories

Archives

October 2025
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (892)
  • Economy (914)
  • Entertainment (21,785)
  • General (17,878)
  • Health (9,955)
  • Lifestyle (927)
  • News (22,149)
  • People (915)
  • Politics (924)
  • Science (16,125)
  • Sports (21,414)
  • Technology (15,894)
  • World (897)

Recent News

National TRAP Program targets ghostly issue with second round of coastal clean up funding – EurekAlert!

National TRAP Program Launches Second Wave of Funding to Combat Ghost Gear on Our Coasts

October 29, 2025
In the Presence of the Minister of Energy, Cisco and King Abdullah University of Science and Technology (KAUST) launch landmark AI Institute to accelerate AI research, development, and talent in Saudi Arabia – Cisco Newsroom

Cisco and KAUST Launch Revolutionary AI Institute to Drive Saudi Arabia’s Innovation and Talent Growth

October 29, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version