* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Wednesday, October 8, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Offset Is Ready To Finalize Divorce With Cardi B for a Major Reason – Yahoo

    Offset Poised to Finalize Divorce from Cardi B for a Major Reason

    Beyond the Stage: 8 Performing Arts Centers Driving Entertainment and Education – Livability.com

    Beyond the Stage: 8 Performing Arts Centers Transforming Entertainment and Education

    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Charlie Hunnam Reflects on Playing a Serial Killer in Monster: The Ed Gein Story – Yahoo

    Charlie Hunnam Reveals the Dark Challenges of Playing a Serial Killer in Monster: The Ed Gein Story

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    Why Taylor Swift Name-Dropped Elizabeth Taylor in Her New Album – Yahoo

    Here’s Why Taylor Swift Dropped Elizabeth Taylor’s Name in Her New Album

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    US and investors gambling on unproven nuclear technology, warn experts – Financial Times

    US and investors gambling on unproven nuclear technology, warn experts – Financial Times

    Is Light-Speed Analog Computing the Future of Technology? – BIOENGINEER.ORG

    Could Light-Speed Analog Computing Transform the Future of Technology?

    ARM Institute opens technology project call to speed submarine manufacturing – The Robot Report

    ARM Institute Unveils Cutting-Edge Technology Project to Revolutionize Submarine Manufacturing

    Forget Cowbells. Cows Wear High-Tech Collars Now. – The New York Times

    Ditch the Cowbells: Discover the High-Tech Collars Transforming Cattle Care

    What the Recent Price Surge Means for Figure Technology Solutions After SEC Settlement – Yahoo Finance

    What the Recent Price Surge Reveals About Figure Technology Solutions Following SEC Settlement

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Offset Is Ready To Finalize Divorce With Cardi B for a Major Reason – Yahoo

    Offset Poised to Finalize Divorce from Cardi B for a Major Reason

    Beyond the Stage: 8 Performing Arts Centers Driving Entertainment and Education – Livability.com

    Beyond the Stage: 8 Performing Arts Centers Transforming Entertainment and Education

    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Charlie Hunnam Reflects on Playing a Serial Killer in Monster: The Ed Gein Story – Yahoo

    Charlie Hunnam Reveals the Dark Challenges of Playing a Serial Killer in Monster: The Ed Gein Story

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    Why Taylor Swift Name-Dropped Elizabeth Taylor in Her New Album – Yahoo

    Here’s Why Taylor Swift Dropped Elizabeth Taylor’s Name in Her New Album

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    US and investors gambling on unproven nuclear technology, warn experts – Financial Times

    US and investors gambling on unproven nuclear technology, warn experts – Financial Times

    Is Light-Speed Analog Computing the Future of Technology? – BIOENGINEER.ORG

    Could Light-Speed Analog Computing Transform the Future of Technology?

    ARM Institute opens technology project call to speed submarine manufacturing – The Robot Report

    ARM Institute Unveils Cutting-Edge Technology Project to Revolutionize Submarine Manufacturing

    Forget Cowbells. Cows Wear High-Tech Collars Now. – The New York Times

    Ditch the Cowbells: Discover the High-Tech Collars Transforming Cattle Care

    What the Recent Price Surge Means for Figure Technology Solutions After SEC Settlement – Yahoo Finance

    What the Recent Price Surge Reveals About Figure Technology Solutions Following SEC Settlement

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

A generative AI develops drug molecules based on the 3D surface of proteins

April 25, 2024
in Science
A generative AI develops drug molecules based on the 3D surface of proteins
Share on FacebookShare on Twitter

Chemists at ETH Zurich have developed a new computer process that allows them to generate active pharmaceutical ingredients quickly and easily. They have created a generative AI that develops drug molecules based on the 3D surface of proteins with which they interact.

For any 3D-shaped protein, the algorithm creates blueprints for potential drug molecules that either boost or stop a protein’s job in the body. Chemists can then synthesize and test these molecules in the laboratory.

The algorithm only needs to know the protein’s 3D shape, and it will make designs for molecules that fit like keys in a lock to that protein.

The novel technique builds on chemists’ decades-long efforts to understand proteins’ three-dimensional structure and find acceptable candidate drug compounds using computers. Until now, this has frequently required arduous human labor, and the search has often produced extremely difficult or impossible-to-synthesize chemicals. In recent years, if AI has been utilized in this process, it has mainly been used to enhance already-existing molecules.

This new generative AI can develop drug molecules from scratch that match the protein structure. It ensures that the molecules can be chemically synthesized right from the start.

Furthermore, the algorithm only recommends compounds that interact very little or not with other proteins and solely with the designated protein at the desired region. 

Scientists created this algorithm by training AI models with information from hundreds of thousands of known interactions between chemical molecules and the corresponding three-dimensional protein structures.

The new process was found to be capable of what it is designed for in testing. The scientists searched for compounds known as PPARs, which interact with proteins. These proteins regulate the body’s metabolism of fats and sugars. By increasing the activity of these proteins, several diabetes medications help cells absorb more sugar and reduce blood sugar levels.

As soon as possible, the AI-generated new molecules that, like the current medications, increase the activity of PPARs without requiring a significant search period. Team members at Roche evaluated the molecules after ETH researchers created them in the lab. They discovered that the novel molecules are stable and safe from the start.

Gisbert Schneider, a Professor at ETH Zurich’s Department of Chemistry and Applied Biosciences, said, “Our work has made the world of proteins accessible for generative AI in drug research. The new algorithm has enormous potential.” This is especially true for all medically relevant proteins in the human body that don’t interact with any known chemical compounds.

Journal Reference:

Atz K, Cotos L, Isert C, Håkansson M, Focht D, Hilleke M, Nippa DF, Iff M, Ledergerber J, Schiebroek CCG, Romeo V, Hiss JA, Merk D, Schneider P, Kuhn B, Grether U, Schneider G: Prospective de novo drug design with deep interactome learning. Nature Communications, 22 April 2024, doi: 10.1038/s41467-​024-47613-w

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Tech Explorist – https://www.techexplorist.com/generative-ai-develops-drug-molecules-based-3d-surface-proteins/83299/#utm_source=rss&utm_medium=rss&utm_campaign=generative-ai-develops-drug-molecules-based-3d-surface-proteins

Tags: developsGenerativescience
Previous Post

How do birds flock? Uncovering aerodynamic mysteries through mathematics

Next Post

Ben White and six England hopefuls are among the Premier League’s most improved players in 2023/24

New Zealand Surprises With Larger Rate Cut as Economic Concerns Mount – Bloomberg.com

New Zealand Surprises Markets with Larger-Than-Expected Rate Cut Amid Rising Economic Concerns

October 8, 2025
Offset Is Ready To Finalize Divorce With Cardi B for a Major Reason – Yahoo

Offset Poised to Finalize Divorce from Cardi B for a Major Reason

October 8, 2025
Health Rounds: Genetics play a role in higher depression risk for women – Reuters

How Genetics Shape Depression Risk in Women: What Everyone Should Understand

October 8, 2025
October 7, 2025 – Federal government shutdown – CNN

October 7, 2025 – Federal government shutdown – CNN

October 8, 2025
Blackwater photos suggest new symbiosis between fish and anemones – EurekAlert!

Breathtaking Blackwater Photos Unveil an Unexpected Alliance Between Fish and Anemones

October 8, 2025
WATCH LIVE: The winner of the Nobel Prize in chemistry is… – PBS

Breaking News: Unveiling the Latest Nobel Prize Winner in Chemistry!

October 8, 2025
Soar through a 1,000-mile-long maze on Mars in this mesmerizing new satellite video – Live Science

Discover a Breathtaking 1,000-Mile-Long Maze on Mars in This Mesmerizing New Satellite Video

October 8, 2025
Video: Dog Sighs in Different Situations Like ‘He Works 9-5′ – Yahoo

Watch This Dog’s Hilarious Sighs That Perfectly Capture Everyday Life Moments

October 8, 2025
US and investors gambling on unproven nuclear technology, warn experts – Financial Times

US and investors gambling on unproven nuclear technology, warn experts – Financial Times

October 8, 2025
Wings, booze and heartbreak – what my research says about the hidden costs of sports fandom – The Conversation

Wings, Booze, and Heartbreak: The Untold Price of Being a Devoted Sports Fan

October 8, 2025

Categories

Archives

October 2025
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (857)
  • Economy (878)
  • Entertainment (21,751)
  • General (17,478)
  • Health (9,920)
  • Lifestyle (890)
  • News (22,149)
  • People (879)
  • Politics (889)
  • Science (16,088)
  • Sports (21,378)
  • Technology (15,858)
  • World (860)

Recent News

New Zealand Surprises With Larger Rate Cut as Economic Concerns Mount – Bloomberg.com

New Zealand Surprises Markets with Larger-Than-Expected Rate Cut Amid Rising Economic Concerns

October 8, 2025
Offset Is Ready To Finalize Divorce With Cardi B for a Major Reason – Yahoo

Offset Poised to Finalize Divorce from Cardi B for a Major Reason

October 8, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version