* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Monday, June 9, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Cisco Partners with Monumental Sports & Entertainment to Power New D.C. Arena – Cisco Newsroom

    Cisco Teams Up with Monumental Sports & Entertainment to Revolutionize the New D.C. Arena Experience

    Middle Eastern Entertainment Headlines at 5:49 a.m. GMT – Yahoo

    Exciting Updates from the Middle Eastern Entertainment Scene!

    Ceramic Dalmatian Entertainment is WLAF’s Business of the Week – WLAF

    Spotlight on Success: Ceramic Dalmatian Entertainment Shines as This Week’s Featured Business!

    Brass Lion Entertainment unveils co-op action RPG Wu-Tang: Rise of the Deceiver – VentureBeat

    Unleash Your Inner Warrior: Discover the Co-Op Action RPG Wu-Tang: Rise of the Deceiver!

    Entertainment lineup released for 2025 Mississippi State Fair – WAPT

    Exciting Entertainment Lineup Unveiled for the 2025 Mississippi State Fair!

    After Denzel Washington Said He Would Be In Black Panther 3, Ryan Coogler Explained Why He’s ‘Fine’ With That Information Being Revealed So Early – Yahoo

    Ryan Coogler Shares Why He’s Cool with Denzel Washington’s Black Panther 3 Reveal!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Technology, Labor Rights, and Political Power in Kenya and Across Africa – Tech Policy Press

    How Technology is Shaping Labor Rights and Political Power Across Africa

    Reeves to Announce £86 Billion for Science and Technology in Spending Review – Bloomberg

    Reeves Set to Unveil Groundbreaking £86 Billion Investment in Science and Technology!

    Innovation at Scale: How P&G Transforms Business Through Technology – Procter & Gamble

    Revolutionizing Business: P&G’s Bold Journey into Technological Innovation

    Drag racer survives frightening airborne crash at World Wide Technology Raceway – FOX 2

    Drag racer survives frightening airborne crash at World Wide Technology Raceway – FOX 2

    Apple Watch and the future of wearable technology in healthcare – MSN

    Revolutionizing Healthcare: The Future of Wearable Technology with Apple Watch

    ECS Professor Pankaj K. Jha Receives NSF Grant to Develop Quantum Technology – Syracuse University News

    Unlocking the Future: ECS Professor Pankaj K. Jha Secures NSF Grant for Groundbreaking Quantum Technology Development

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Cisco Partners with Monumental Sports & Entertainment to Power New D.C. Arena – Cisco Newsroom

    Cisco Teams Up with Monumental Sports & Entertainment to Revolutionize the New D.C. Arena Experience

    Middle Eastern Entertainment Headlines at 5:49 a.m. GMT – Yahoo

    Exciting Updates from the Middle Eastern Entertainment Scene!

    Ceramic Dalmatian Entertainment is WLAF’s Business of the Week – WLAF

    Spotlight on Success: Ceramic Dalmatian Entertainment Shines as This Week’s Featured Business!

    Brass Lion Entertainment unveils co-op action RPG Wu-Tang: Rise of the Deceiver – VentureBeat

    Unleash Your Inner Warrior: Discover the Co-Op Action RPG Wu-Tang: Rise of the Deceiver!

    Entertainment lineup released for 2025 Mississippi State Fair – WAPT

    Exciting Entertainment Lineup Unveiled for the 2025 Mississippi State Fair!

    After Denzel Washington Said He Would Be In Black Panther 3, Ryan Coogler Explained Why He’s ‘Fine’ With That Information Being Revealed So Early – Yahoo

    Ryan Coogler Shares Why He’s Cool with Denzel Washington’s Black Panther 3 Reveal!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Technology, Labor Rights, and Political Power in Kenya and Across Africa – Tech Policy Press

    How Technology is Shaping Labor Rights and Political Power Across Africa

    Reeves to Announce £86 Billion for Science and Technology in Spending Review – Bloomberg

    Reeves Set to Unveil Groundbreaking £86 Billion Investment in Science and Technology!

    Innovation at Scale: How P&G Transforms Business Through Technology – Procter & Gamble

    Revolutionizing Business: P&G’s Bold Journey into Technological Innovation

    Drag racer survives frightening airborne crash at World Wide Technology Raceway – FOX 2

    Drag racer survives frightening airborne crash at World Wide Technology Raceway – FOX 2

    Apple Watch and the future of wearable technology in healthcare – MSN

    Revolutionizing Healthcare: The Future of Wearable Technology with Apple Watch

    ECS Professor Pankaj K. Jha Receives NSF Grant to Develop Quantum Technology – Syracuse University News

    Unlocking the Future: ECS Professor Pankaj K. Jha Secures NSF Grant for Groundbreaking Quantum Technology Development

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Bad News: A Cure for Malaria Is Likely Farther Away Than Scientists Thought

February 2, 2024
in Science
Bad News: A Cure for Malaria Is Likely Farther Away Than Scientists Thought
Share on FacebookShare on Twitter

Zika Malaria Mosquito Virus Concept

A groundbreaking study overturns previous assumptions about a blood type’s resistance to malaria, revealing that even individuals with the “silent Duffy blood group” are susceptible to infection. This finding underscores the complexity of malaria resistance and the importance of advanced diagnostic methods in a changing global health landscape.

People with blood trait thought to prevent the disease still became infected; the question now is ‘how?’

For decades, researchers dedicated to finding a cure for malaria believed they had pinpointed a blood type that appeared to offer protection against the disease.

However, a recent publication in Cell Host & Microbe has revealed that even individuals with this supposedly protective blood type can become infected. The question now is, “how?”

“This might mean that the specific gene mutation related to this blood type doesn’t completely stop malaria, or the malaria bug might have found another way to get into the blood cells,” said Peter Zimmerman, a pathology professor at the Case Western Reserve University School of Medicine and the study’s senior author. “It’s a big deal because it might change how we try to get rid of this type of malaria parasite.”

Peter Zimmerman

Peter Zimmerman. Credit: Case Western Reserve University

“This malaria parasite, called Plasmodium vivax—or P. vivax—used to be common in Northeast Ohio,” said Christopher King, a study co-investigator and pathology professor. “And it was transmitted within the United States—Florida and Texas—this summer for the first time in 20 years.

“We have known,” King said, “that the United States is at risk of re-introduction of malaria with climate changes and increasing immigration and traveling from malaria-endemic areas.”

Study collaborators include researchers from France (Célia Dechavanne and Benoit Gamain, from the National Institute of Blood Transfusion, INSERM/Paris Diderot University); and Madagascar (Arsène Ratsimbasoa, from the University of Fianarantsoa).

The study

“Malaria researchers have been trying to chip away at understanding resistance and susceptibility of P. vivax infection of African people for more than 100 years,” Zimmerman said. “More than 2.5 billion people may live in Africa and Southeast Asia where the parasite is found. Hundreds of thousands of people a year die from malaria. In general, malaria is one of the big three global-health infectious diseases—malaria, tuberculous and HIV/AIDS.”

The team is studying a specific blood type (Fy-negative) in the blood of most people in Africa and of African origin, called “the silent Duffy blood group.” Duffy-negative people have a mutation in the DNA code (GATA-1) that results in the protein not being expressed on the surface of red blood cells.

The researchers did experiments using blood cells grown in the lab and cells taken from bone marrow to study the Duffy-silent blood type.

“Surprisingly, we found that even when people are missing the GATA-1 DNA code, the Duffy protein sometimes shows up on their red blood cells,” Zimmerman said. “Our findings suggest that the bone marrow and other places where blood cells are first made are important for the malaria parasite to find the red cells with the Duffy protein, to grow and cause sickness.”

In other experiments in the lab, they examined the blood of people with Duffy silent blood type. They noticed the P. vivax malaria infection was often detected using a special test rather than the usual microscope test.

This means that people with Duffy-silent blood type can still have the infection, but it’s not always easy to see in regular blood tests. In other words, they found that P. vivax can invade the red blood cells of people with the Duffy-silent trait. Also, if they have the infection in the bone marrow, they produce the transmissible form of the parasite. Mosquitoes can acquire it and cause infections in other people.

“This discovery raises questions about how malaria parasites cause infection and sickness, especially because some people with the infection don’t show many signs in their blood,” Zimmerman said. “We need to look at the blood more closely to understand better how widespread and serious this type of malaria is in people with the Duffy-silent trait.”

Reference: “Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals” by Celia Dechavanne, Sebastien Dechavanne, Jürgen Bosch, Sylvain Metral, Karli R. Redinger, Quentin D. Watson, Arsene C. Ratsimbasoa, Brooke Roeper, Sushma Krishnan, Rich Fong, Seth Bennett, Lenore Carias, Edwin Chen, Nichole D. Salinas, Anil Ghosh, Niraj H. Tolia, Philip G. Woost, James W. Jacobberger, Yves Colin, Benoit Gamain, Christopher L. King and Peter A. Zimmerman, 5 December 2023, Cell Host & Microbe.
DOI: 10.1016/j.chom.2023.10.019

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : SciTechDaily – https://scitechdaily.com/bad-news-a-cure-for-malaria-is-likely-farther-away-than-scientists-thought/

Tags: LikelyMalariascience
Previous Post

2024 Total Solar Eclipse: Broader Path, Longer Totality, and Increased Solar Activity

Next Post

Decoding Metastasis: Unveiling the Secrets Behind Cancer’s Stealthy Spread

Technology, Labor Rights, and Political Power in Kenya and Across Africa – Tech Policy Press

How Technology is Shaping Labor Rights and Political Power Across Africa

June 9, 2025
PCT Day 16-22 — Ecological Whiplash – The Trek

PCT Day 16-22 — Ecological Whiplash – The Trek

June 9, 2025
Attacks on science are attacks on making and keeping America great: op-ed – AL.com

Attacks on science are attacks on making and keeping America great: op-ed – AL.com

June 9, 2025
Science Confirms: Social Media Could Be Making Kids Depressed – SciTechDaily

Science Confirms: Social Media Could Be Making Kids Depressed – SciTechDaily

June 9, 2025
ZEL Mallorca, the active lifestyle brand of Meliá unveils bold and vibrant signature suite in Mallorca collaboration with Parisian artistic duo, Pangea. – Edomex Al Día

ZEL Mallorca, the active lifestyle brand of Meliá unveils bold and vibrant signature suite in Mallorca collaboration with Parisian artistic duo, Pangea. – Edomex Al Día

June 9, 2025
Power up your play with Nintendo Switch 2 and Mario Kart World launching today – News – Nintendo Official Site – Nintendo

Get Ready to Race: Nintendo Switch 2 and Mario Kart World Launch Today!

June 9, 2025
Lebanon aims to lure back wealthy Gulf tourists to jump-start its war-torn economy – Los Angeles Times

Lebanon Sets Sights on Wealthy Gulf Tourists to Revive Its War-Torn Economy

June 8, 2025
Cisco Partners with Monumental Sports & Entertainment to Power New D.C. Arena – Cisco Newsroom

Cisco Teams Up with Monumental Sports & Entertainment to Revolutionize the New D.C. Arena Experience

June 8, 2025
Couples who cuddle before sleep reap key health benefits, study reveals – Fox News

Couples who cuddle before sleep reap key health benefits, study reveals – Fox News

June 8, 2025
‘Damnit, get somebody in there’: Jimmy Patronis presses Ron DeSantis on CFO vacancy – Florida Politics

Damnit, Get Somebody In There!’ Jimmy Patronis Urges Ron DeSantis to Fill CFO Vacancy Immediately

June 8, 2025

Categories

Archives

June 2025
MTWTFSS
 1
2345678
9101112131415
16171819202122
23242526272829
30 
« May    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (678)
  • Economy (691)
  • Entertainment (21,597)
  • General (15,281)
  • Health (9,733)
  • Lifestyle (695)
  • News (22,149)
  • People (692)
  • Politics (698)
  • Science (15,910)
  • Sports (21,193)
  • Technology (15,678)
  • World (676)

Recent News

Technology, Labor Rights, and Political Power in Kenya and Across Africa – Tech Policy Press

How Technology is Shaping Labor Rights and Political Power Across Africa

June 9, 2025
PCT Day 16-22 — Ecological Whiplash – The Trek

PCT Day 16-22 — Ecological Whiplash – The Trek

June 9, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version