* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Wednesday, September 17, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Gen V Season 2: What is The Odessa Project? – yahoo.com

    Gen V Season 2: Unlocking the Secrets of The Odessa Project

    PENN Entertainment stock rating reiterated at Market Outperform by JMP – Investing.com

    PENN Entertainment Stock Rated a Market Outperformer by Experts

    Here’s how NJ’s once-vibrant nightclub scene was born and why it died – Bergen Record

    The Rise and Fall of New Jersey’s Once-Vibrant Nightclub Scene: What Happened?

    The Emmys are back: Viewership soars to highest numbers in 4 years – yahoo.com

    The Emmys Return with a Bang: Viewership Hits a 4-Year High

    From Spinal Tap II to Ed Sheeran : your complete entertainment guide to the week ahead – The Guardian

    Fall’s Hottest Ski Films Are Going on Tour—Here’s the List – yahoo.com

    Experience the Thrill: Fall’s Hottest Ski Films Hit the Road-Don’t Miss the Tour!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    City IT presented Best of North Carolina Technology Award – RaleighNC.gov

    City IT Honored with Best of North Carolina Technology Award

    LELO Releases 2025 Futurist Report: Intergenerational Views on Relationships, Sex, and Technology – PR Newswire

    Exploring the Future: How Different Generations View Relationships, Sex, and Technology in 2025

    Will New Big Technology Engagements Reshape Innodata’s Growth Path? – Yahoo Finance

    Could New Major Tech Partnerships Propel Innodata to Unprecedented Growth?

    Unlocking AI Success: How People, Process, and Technology Form the Ultimate Triangle

    Billion-dollar coffins? New technology could make oceans transparent and Aukus submarines vulnerable – The Guardian

    Billion-Dollar Coffins? How New Technology Could Make Oceans Transparent and Expose Submarines

    What if artificial intelligence is just a “normal” technology? – The Economist

    What if artificial intelligence is just a “normal” technology? – The Economist

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Gen V Season 2: What is The Odessa Project? – yahoo.com

    Gen V Season 2: Unlocking the Secrets of The Odessa Project

    PENN Entertainment stock rating reiterated at Market Outperform by JMP – Investing.com

    PENN Entertainment Stock Rated a Market Outperformer by Experts

    Here’s how NJ’s once-vibrant nightclub scene was born and why it died – Bergen Record

    The Rise and Fall of New Jersey’s Once-Vibrant Nightclub Scene: What Happened?

    The Emmys are back: Viewership soars to highest numbers in 4 years – yahoo.com

    The Emmys Return with a Bang: Viewership Hits a 4-Year High

    From Spinal Tap II to Ed Sheeran : your complete entertainment guide to the week ahead – The Guardian

    Fall’s Hottest Ski Films Are Going on Tour—Here’s the List – yahoo.com

    Experience the Thrill: Fall’s Hottest Ski Films Hit the Road-Don’t Miss the Tour!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    City IT presented Best of North Carolina Technology Award – RaleighNC.gov

    City IT Honored with Best of North Carolina Technology Award

    LELO Releases 2025 Futurist Report: Intergenerational Views on Relationships, Sex, and Technology – PR Newswire

    Exploring the Future: How Different Generations View Relationships, Sex, and Technology in 2025

    Will New Big Technology Engagements Reshape Innodata’s Growth Path? – Yahoo Finance

    Could New Major Tech Partnerships Propel Innodata to Unprecedented Growth?

    Unlocking AI Success: How People, Process, and Technology Form the Ultimate Triangle

    Billion-dollar coffins? New technology could make oceans transparent and Aukus submarines vulnerable – The Guardian

    Billion-Dollar Coffins? How New Technology Could Make Oceans Transparent and Expose Submarines

    What if artificial intelligence is just a “normal” technology? – The Economist

    What if artificial intelligence is just a “normal” technology? – The Economist

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Breakthrough in Arthritis Treatment: JAK Inhibitors Prove Highly Effective in Japanese Study

January 3, 2024
in Science
Breakthrough in Arthritis Treatment: JAK Inhibitors Prove Highly Effective in Japanese Study
Share on FacebookShare on Twitter

Arthritis Knee Pain X-ray Illustration

A new study has confirmed the effectiveness of JAK inhibitors in treating rheumatoid arthritis. The Japanese multicenter, retrospective study found high remission and low disease activity rates among patients, with the majority continuing treatment. This success highlights the potential of JAK inhibitors as a favorable alternative to conventional treatments, which often lead to reduced effectiveness and discomfort over time.

A new study published in the journal Rheumatology reveals that JAK inhibitors, commonly used to treat arthritis patients, are indeed effective. Despite initial concerns about their effectiveness, this multicenter, retrospective study conducted by Japanese researchers has shown impressive remission rates in patients, with most opting to continue the treatment

Understanding Rheumatoid Arthritis and Current Treatments

Rheumatoid arthritis is a common autoimmune disease characterized by chronic inflammation of joint linings and results in progressive joint destruction and other systemic complications. The use of biological disease-modifying drugs enables patients to enjoy the achievement of low disease activity and remission. But clinics must administer such drugs through subcutaneous or intravenous routes, which is unpleasant for patients, and over time these drugs commonly become less effective.

Recently scientists have developed Janus kinase (JAK) inhibitors for arthritis treatment. Patients take such drugs orally. Previous research has demonstrated the efficacy and safety of JAK inhibitors in randomized controlled trials.

However, some researchers have questioned the potential efficacy of JAK inhibitors for widespread patient use. In practice, doctors mostly treat patients with JAK inhibitors precisely because those patients have other health problems and so conventional drugs like methotrexate are less effective on them. Real-world patients have distinctive characteristics compared with the patients recruited in randomized controlled trials.

The Japanese Study on JAK Inhibitors

In the present multicenter, retrospective study, researchers using data from 622 patients treated at seven major university hospitals in Japan compared the efficacy and safety of four common JAK inhibitors: tofacitinib, baricitinib, peficitinib, and upadacitinib.

The researchers here found that approximately one in three patients reached remission, three in four reached at least low disease activity, with both numbers representing impressive efficacy. They noted that more than 80% of the patients were still on the JAK inhibitor drugs after six months.

They believe that this is particularly relevant given that immunological secondary treatment failure, where drugs cease to be effective because they produce adverse immune system responses in patients, cannot occur with these oral medications. Immunological secondary treatment failure is common in patients who treat their arthritis with drugs like methotrexate.

Reference: “Real-world comparative study of the efficacy of Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study” by Shinya Hayashi, Shotaro Tachibana, Toshihisa Maeda, Mai Yamashita, Iku Shirasugi, Yuzuru Yamamoto, Hirotaka Yamada, Takaichi Okano, Keisuke Nishimura, Yo Ueda, Sadao Jinnno, Jun Saegusa, Wataru Yamamoto, Koichi Murata, Takayuki Fujii, Kenichiro Hata, Ayaka Yoshikawa, Kosuke Ebina, Yuki Etani, Naofumi Yoshida, Hideki Amuro, Motomu Hashimoto, Ryota Hara, Masaki Katayama, Tadashi Okano and Ryosuke Kuroda, 01 November 2023, Rheumatology.
DOI: 10.1093/rheumatology/kead543

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : SciTechDaily – https://scitechdaily.com/breakthrough-in-arthritis-treatment-jak-inhibitors-prove-highly-effective-in-japanese-study/

Tags: ArthritisBreakthroughscience
Previous Post

The ‘Accidental Activist’ Who Changed the Face of Mathematics

Next Post

Space Rocks to Life Blocks: Meteorites Likely Source of Nitrogen for Early Earth

Indonesia ponders pro-growth mandate for central bank as economy flags – Financial Times

Indonesia ponders pro-growth mandate for central bank as economy flags – Financial Times

September 17, 2025
Gen V Season 2: What is The Odessa Project? – yahoo.com

Gen V Season 2: Unlocking the Secrets of The Odessa Project

September 17, 2025
Is the Economy as Healthy as Trump Claims? – The New York Times

Is the Economy as Healthy as Trump Claims? – The New York Times

September 17, 2025
Inside Stephen A. Smith’s near-$40M-a-year bonanza as he launches into political prime time – The New York Times

Inside Stephen A. Smith’s near-$40M-a-year bonanza as he launches into political prime time – The New York Times

September 17, 2025
Torch Lake faces ecological challenges from invasive Quagga Mussels – WPBN

Torch Lake Fights Back Against the Growing Threat of Invasive Quagga Mussels

September 17, 2025
New Data Science Minor Prepares Students for Data-Driven World – CSUF News

Unlock Your Potential with the Exciting New Data Science Minor Designed for a Data-Driven Future

September 17, 2025
Miami University’s Cleveland Clinic Health Sciences and Wellness facility. – Cleveland Clinic Newsroom

Explore Miami University’s Exciting New Cleveland Clinic Health Sciences and Wellness Center

September 17, 2025
This Is The Most Popular Soup In The U.S. Right Now—And It’s A Fall Classic – yahoo.com

This Fall’s Most Beloved Soup Is Taking the U.S. by Storm

September 17, 2025
City IT presented Best of North Carolina Technology Award – RaleighNC.gov

City IT Honored with Best of North Carolina Technology Award

September 17, 2025

Lillie C. Ainscough – altoonamirror.com

September 17, 2025

Categories

Archives

September 2025
MTWTFSS
1234567
891011121314
15161718192021
22232425262728
2930 
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (823)
  • Economy (843)
  • Entertainment (21,722)
  • General (17,085)
  • Health (9,888)
  • Lifestyle (857)
  • News (22,149)
  • People (847)
  • Politics (853)
  • Science (16,054)
  • Sports (21,343)
  • Technology (15,825)
  • World (826)

Recent News

Indonesia ponders pro-growth mandate for central bank as economy flags – Financial Times

Indonesia ponders pro-growth mandate for central bank as economy flags – Financial Times

September 17, 2025
Gen V Season 2: What is The Odessa Project? – yahoo.com

Gen V Season 2: Unlocking the Secrets of The Odessa Project

September 17, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version