* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Saturday, May 31, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Entertainment: On Your Marks, Get Set, Beer Run! – Urban Milwaukee

    Get Ready to Race: The Ultimate Beer Run Experience Awaits!

    Rachel Guttman Launches Entertainment Law Firm Gutt Law, PLLC [Exclusive] – MusicRow.com

    Rachel Guttman Unveils Exciting New Entertainment Law Firm: Gutt Law, PLLC!

    HYBE Cashes In: Offloads Final Stake in K-Pop Rival SM Entertainment for $177 Million!

    Allied Gaming & Entertainment Receives Expected Nasdaq Notice Regarding Delayed Quarterly Report – Business Wire

    Allied Gaming & Entertainment Faces Nasdaq Notice Over Delayed Quarterly Report

    Weekly Entertainment Report May 29-June 1: Where to find lively arts, music, and shows – Manchester Ink Link

    Weekly Entertainment Report May 29-June 1: Where to find lively arts, music, and shows – Manchester Ink Link

    Aziz Ansari made Keanu Reeves Indian food so he wouldn’t feel ‘freaked out’ directing him in Good Fortune (exclusive) – Entertainment Weekly

    Aziz Ansari Whips Up Indian Cuisine for Keanu Reeves to Ease Directing Jitters in Good Fortune

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology

    Revolutionary Harvesting Technology Promises to Slash CAR-T Manufacturing Costs!

    Stop the Machines: The Rise of Anti-Technology Extremism – International Centre for Counter-Terrorism – ICCT

    Unplugged: The Surge of Anti-Technology Extremism

    Finland to head EU’s quantum defense technology project – Latest news from Azerbaijan

    Finland Takes the Lead in Pioneering EU’s Quantum Defense Technology Initiative!

    i3D Robotics Unveils Breakthrough Glass Defect Detection Technology – USGlass Magazine

    Revolutionary Glass Defect Detection Technology Unveiled by i3D Robotics!

    4Liberty Announces Collaboration with Itron to Drive Innovation in Utility Technology Adoption and Optimization – FinancialContent

    4Liberty Partners with Itron to Revolutionize Utility Technology and Boost Innovation

    Q1 2025 Quantum Technology Investment: What’s Driving the Surge in Quantum Investment? – The Quantum Insider

    Unleashing the Future: Exploring the Surge in Quantum Technology Investments for Q1 2025

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Entertainment: On Your Marks, Get Set, Beer Run! – Urban Milwaukee

    Get Ready to Race: The Ultimate Beer Run Experience Awaits!

    Rachel Guttman Launches Entertainment Law Firm Gutt Law, PLLC [Exclusive] – MusicRow.com

    Rachel Guttman Unveils Exciting New Entertainment Law Firm: Gutt Law, PLLC!

    HYBE Cashes In: Offloads Final Stake in K-Pop Rival SM Entertainment for $177 Million!

    Allied Gaming & Entertainment Receives Expected Nasdaq Notice Regarding Delayed Quarterly Report – Business Wire

    Allied Gaming & Entertainment Faces Nasdaq Notice Over Delayed Quarterly Report

    Weekly Entertainment Report May 29-June 1: Where to find lively arts, music, and shows – Manchester Ink Link

    Weekly Entertainment Report May 29-June 1: Where to find lively arts, music, and shows – Manchester Ink Link

    Aziz Ansari made Keanu Reeves Indian food so he wouldn’t feel ‘freaked out’ directing him in Good Fortune (exclusive) – Entertainment Weekly

    Aziz Ansari Whips Up Indian Cuisine for Keanu Reeves to Ease Directing Jitters in Good Fortune

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology

    Revolutionary Harvesting Technology Promises to Slash CAR-T Manufacturing Costs!

    Stop the Machines: The Rise of Anti-Technology Extremism – International Centre for Counter-Terrorism – ICCT

    Unplugged: The Surge of Anti-Technology Extremism

    Finland to head EU’s quantum defense technology project – Latest news from Azerbaijan

    Finland Takes the Lead in Pioneering EU’s Quantum Defense Technology Initiative!

    i3D Robotics Unveils Breakthrough Glass Defect Detection Technology – USGlass Magazine

    Revolutionary Glass Defect Detection Technology Unveiled by i3D Robotics!

    4Liberty Announces Collaboration with Itron to Drive Innovation in Utility Technology Adoption and Optimization – FinancialContent

    4Liberty Partners with Itron to Revolutionize Utility Technology and Boost Innovation

    Q1 2025 Quantum Technology Investment: What’s Driving the Surge in Quantum Investment? – The Quantum Insider

    Unleashing the Future: Exploring the Surge in Quantum Technology Investments for Q1 2025

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Gut bacteria sometimes get people drunk, leading to DUIs and liver disease

May 5, 2024
in Science
Gut bacteria sometimes get people drunk, leading to DUIs and liver disease
Share on FacebookShare on Twitter

A white man with a beard sits in the driver's seat of a car clutching his forehead. A hand holds a breathalyzer test toward him

People with a condition called auto-brewery syndrome carry microbes that produce high levels of alcohol when breaking down sugars and carbohydrates.
(Image credit: Shutterstock)

Imagine you’re a police officer. You spot a car that’s swerving all over the road. You pull the driver over and they’re clearly intoxicated. With slurred speech, they swear that they haven’t had a drop of alcohol all day. Would you believe them?

In 2024, a Belgian man was acquitted after he was cited three times for DUI within four years. Though his job at a brewery likely raised suspicions, he insisted that he hadn’t been drinking. Three doctors confirmed that he suffered from a condition called auto-brewery syndrome and was unaware. People with this syndrome carry microbes in their intestines that produce abnormally high levels of alcohol when breaking down sugars and carbohydrates.

Though it’s a rare condition, a woman was acquitted of her DUI charge in 2016 after doctors diagnosed her with the same syndrome. She had a blood alcohol level four times the legal limit.

I am a microbiologist who is intrigued by the roles the gut microbiome plays in human health. As the author of the book “Pleased to Meet Me: Genes, Germs, and the Curious Forces That Make Us Who We Are,” I have done extensive research into how your microbiome affects your health, mood and behavior. It turns out the specific species of bacteria in your intestines at the root of auto-brewery syndrome may also cause fatty liver disease by producing high levels of alcohol.

Diseased liver, without drinking

The accumulation of excess fats in the liver can cause serious health problems, including inflammation. This can lead to cirrhosis, or scarring, and liver cancer. Most people associate fatty liver disease with alcoholism. However, metabolic dysfunction-associated steatotic liver disease, or MASLD, arises without excessive alcohol intake. Formerly known as nonalcoholic fatty liver disease, this condition affects 80 million to 100 million Americans.

There appear to be multiple causes of MASLD, such as obesity, insulin resistance, high cholesterol and hepatitis C infection. Microbes may be another.

In a 2019 study, physicians identified a patient who was suffering from both auto-brewery syndrome and severe MASLD. When researchers examined stool samples from the patient, they found a species of bacteria called Klebsiella pneumoniae. This particular strain of K. pneumoniae was making between four and six times the quantity of alcohol that strains of the same bacteria make in healthy people. Examining a cohort of 43 other patients with MASLD, they discovered that 61% of participants possessed K. pneumoniae excreting unusually high amounts of alcohol. Among the 48 healthy people included as controls, only 6% had such bacteria.

Get the world’s most fascinating discoveries delivered straight to your inbox.

The team noted that K. pneumoniae bacteria was only slightly more abundant in the intestines of MASLD patients. It was the quantity of alcohol that the microbes produced that differed. But could the excessive alcohol the bacteria was making actually give rise to fatty liver?

A microbrewery in the gut

To understand whether microbes were really to blame for fatty liver, the scientists fed the high-alcohol-producing K. pneumoniae bacteria to healthy mice. Within one month, these mice developed measurable symptoms of fatty liver, which progressed to cirrhosis within two months. The bacteria-triggered liver disease followed the same timeline the researchers observed when they fed the mice pure alcohol.

Further supporting their hypothesis, transferring intestinal material from either mice or humans with MASLD into healthy mice led them to develop fatty liver damage.

Finally, researchers treated the intestinal material harvested from MASLD mice with a virus that kills only Klebsiella. When intestinal material free of Klebsiella was transplanted into healthy mice, they didn’t develop any disease.

Their results suggest that certain K. pneumoniae bacteria make excessive alcohol that can lead to fatty liver. This also means that some K. pneumoniae-induced cases of fatty liver might be treatable with antibiotics. Indeed, giving the antibiotic imipenem to mice with K. pneumoniae-induced fatty liver reversed progression of the disease.

Since K. pneumoniae converts sugar to alcohol, physicians may be able to diagnose this form of fatty liver with a simple blood test to measure blood alcohol levels in response to sugar. The researchers showed that mice harboring the alcohol-producing Klebsiella bacteria became inebriated and showed increased blood alcohol levels after consuming sugar.

It isn’t clear whether this phenomenon is widespread. Klebsiella bacteria is commonly found in human intestines, but it is unknown why some people harbor strains that make high levels of alcohol.

In the bigger picture, the study further illustrates the importance of the microbiome in regulating mood and behavior. Some people may possess intestinal microbes secreting enough alcohol to make them act drunk when, in fact, they ate only a sweet dessert, as was the case with the woman charged with DUI. The Belgian man is also trying to minimize the amount of alcohol his gut microbes make through dieting and medication. Whether these people have a greater tolerance for alcohol through constant exposure is another question.

This article, originally published Sep. 30, 2019, has been updated to include details from a 2024 DUI case.

This edited article is republished from The Conversation under a Creative Commons license. Read the original article.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Live Science – https://www.livescience.com/health/gut-bacteria-sometimes-get-people-drunk-leading-to-duis-and-liver-disease

Tags: BacteriascienceSometimes
Previous Post

Why do dogs sniff each other’s butts?

Next Post

Space photo of the week: A planet-size explosion rocks the sun’s ‘mossy’ corona

Predicting invasion costs from sparse data – Nature

Unlocking the Secrets of Invasion Costs: Insights from Sparse Data

May 31, 2025
High school science teacher’s advice leaves lasting mark on student – MSN

How a High School Science Teacher Inspired a Lifelong Passion for Learning

May 31, 2025
RFK Jr. threatens to bar government scientists from publishing in leading medical journals – Politico

RFK Jr. Vows to Restrict Government Scientists from Publishing in Top Medical Journals

May 31, 2025
Monique Thomas gifts love with Stem & Story Studio – Jamaica Gleaner

Monique Thomas gifts love with Stem & Story Studio – Jamaica Gleaner

May 31, 2025
Texas vs. Florida: 2025 Women’s College World Series Game 1 | Extended highlights – NCAA.com

Texas vs. Florida: 2025 Women’s College World Series Game 1 | Extended highlights – NCAA.com

May 31, 2025
Proposed URI medical school could fill doctor shortage, boost economy, draft report finds – The Public’s Radio

New URI Medical School: A Solution to Doctor Shortages and Economic Growth!

May 31, 2025
Entertainment: On Your Marks, Get Set, Beer Run! – Urban Milwaukee

Get Ready to Race: The Ultimate Beer Run Experience Awaits!

May 31, 2025
Trump administration ‘MAHA’ health report cited nonexistent studies – Reuters

Trump Administration’s ‘MAHA’ Health Report: Uncovering the Truth Behind Questionable Studies

May 31, 2025
Tributes pour in honoring legacy of legendary politician John Thrasher – Florida Politics

Celebrating the Enduring Legacy of Legendary Politician John Thrasher

May 31, 2025

Revolutionary Harvesting Technology Promises to Slash CAR-T Manufacturing Costs!

May 31, 2025

Categories

Archives

May 2025
MTWTFSS
 1234
567891011
12131415161718
19202122232425
262728293031 
« Apr    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (653)
  • Economy (668)
  • Entertainment (21,574)
  • General (15,252)
  • Health (9,710)
  • Lifestyle (670)
  • News (22,149)
  • People (670)
  • Politics (676)
  • Science (15,890)
  • Sports (21,172)
  • Technology (15,655)
  • World (656)

Recent News

Predicting invasion costs from sparse data – Nature

Unlocking the Secrets of Invasion Costs: Insights from Sparse Data

May 31, 2025
High school science teacher’s advice leaves lasting mark on student – MSN

How a High School Science Teacher Inspired a Lifelong Passion for Learning

May 31, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version