* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Tuesday, October 7, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Charlie Hunnam Reflects on Playing a Serial Killer in Monster: The Ed Gein Story – Yahoo

    Charlie Hunnam Reveals the Dark Challenges of Playing a Serial Killer in Monster: The Ed Gein Story

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    Why Taylor Swift Name-Dropped Elizabeth Taylor in Her New Album – Yahoo

    Here’s Why Taylor Swift Dropped Elizabeth Taylor’s Name in Her New Album

    Al Roker Gives Olivia Dean an Unexpected ‘New Job’ on the ‘Today’ Show – Yahoo

    Al Roker Shocks Olivia Dean with an Exciting New Role on the ‘Today’ Show

    Books about the arts and some haunts for a Denton October – Denton Record-Chronicle

    Uncover Artistic Treasures and Spooky Adventures to Experience in Denton This October

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    ARM Institute opens technology project call to speed submarine manufacturing – The Robot Report

    ARM Institute Unveils Cutting-Edge Technology Project to Revolutionize Submarine Manufacturing

    Forget Cowbells. Cows Wear High-Tech Collars Now. – The New York Times

    Ditch the Cowbells: Discover the High-Tech Collars Transforming Cattle Care

    What the Recent Price Surge Means for Figure Technology Solutions After SEC Settlement – Yahoo Finance

    What the Recent Price Surge Reveals About Figure Technology Solutions Following SEC Settlement

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    Technology Is Becoming More Important Than Humans In CX – No Jitter

    Technology Is Becoming More Important Than Humans In CX – No Jitter

    A Tech Expo Shows What China Can Make, but Not Who’ll Buy It All – The New York Times

    Inside China’s Tech Expo: Cutting-Edge Innovations Face Uncertain Demand

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Row K Entertainment Emerges as Major New Hollywood Buyer With Splashy TIFF Shopping Spree – TheWrap

    Charlie Hunnam Reflects on Playing a Serial Killer in Monster: The Ed Gein Story – Yahoo

    Charlie Hunnam Reveals the Dark Challenges of Playing a Serial Killer in Monster: The Ed Gein Story

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    “Reba” cast, then and now: See the stars 24 years later (and who’s reunited for another show) – Yahoo

    Why Taylor Swift Name-Dropped Elizabeth Taylor in Her New Album – Yahoo

    Here’s Why Taylor Swift Dropped Elizabeth Taylor’s Name in Her New Album

    Al Roker Gives Olivia Dean an Unexpected ‘New Job’ on the ‘Today’ Show – Yahoo

    Al Roker Shocks Olivia Dean with an Exciting New Role on the ‘Today’ Show

    Books about the arts and some haunts for a Denton October – Denton Record-Chronicle

    Uncover Artistic Treasures and Spooky Adventures to Experience in Denton This October

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    ARM Institute opens technology project call to speed submarine manufacturing – The Robot Report

    ARM Institute Unveils Cutting-Edge Technology Project to Revolutionize Submarine Manufacturing

    Forget Cowbells. Cows Wear High-Tech Collars Now. – The New York Times

    Ditch the Cowbells: Discover the High-Tech Collars Transforming Cattle Care

    What the Recent Price Surge Means for Figure Technology Solutions After SEC Settlement – Yahoo Finance

    What the Recent Price Surge Reveals About Figure Technology Solutions Following SEC Settlement

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    MAC Brings iPad Technology to Football Sidelines Across All 13 Member Schools – Sports Video Group

    Technology Is Becoming More Important Than Humans In CX – No Jitter

    Technology Is Becoming More Important Than Humans In CX – No Jitter

    A Tech Expo Shows What China Can Make, but Not Who’ll Buy It All – The New York Times

    Inside China’s Tech Expo: Cutting-Edge Innovations Face Uncertain Demand

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

High cholesterol and blood pressure raise lifelong heart disease risk

December 30, 2023
in Science
High cholesterol and blood pressure raise lifelong heart disease risk
Share on FacebookShare on Twitter

High cholesterol (LDL-C) and high systolic blood pressure (SBP) are the main global causes of coronary heart disease (CHD). It is still unclear- how they affect CHD risk at different life stages.

A new study aimed to investigate whether genetically mediated SBP/LDL-C is associated with the risk of CHD throughout life. To do so, scientists assessed the impact of SBP and LDL-C at a younger age on the risk of CHD independent of later age SBP and LDL-C. 

Current approaches to lowering cholesterol and blood pressure rely on short-term clinical trials. If prolonged exposure to high levels, as suggested by MR studies, has a cumulative impact, it could significantly influence coronary heart disease (CHD) management. Treating low-risk and younger patients earlier might be beneficial if there are added advantages to controlling risk factors over time.

Researchers performed a Mendelian randomization analysis with data from the UK Biobank, involving 136,648 participants for LDL-C, 135,431 for SBP, and 24,052 CHD cases. The study aimed to evaluate how the duration of exposure to these risk factors affects CHD risk, with analyses stratified by age at enrollment. Univariable analyses consistently showed a link between higher LDL-C and SBP exposure and an increased likelihood of developing CHD in individuals.

BP measurements were performed twice after the participant had rested for at least 5 minutes in the seated position with a digital sphygmomanometer, and the average of the two measurements was used for the analyses.

LDL-C levels were directly measured in mmol/L using Enzymatic Selective Protection analysis on the Beckman Coulter AU5800 platform. If participants reported using cholesterol-lowering medication, LDL-C levels were divided by 0.7. For those using blood pressure-lowering medication, 15 mmHg was added to the measured systolic blood pressure.

The population was categorized by age at enrollment: ≤55 years, 55–60 years, 61–65 years, and ≥65 years. To avoid overlapping genetic associations in univariable MR analysis, participants in each age group were randomly split into two subgroups for exposure (SBP or LDL-C) and outcome (CHD) analysis. This ensured that each participant contributed to only one subgroup, preventing overlap in genetic associations for exposure and outcome.

The main study outcome was coronary heart disease (CHD), defined as a composite of coronary death, nonfatal myocardial infarction, or coronary revascularization. Mean systolic blood pressure (SBP) rose with advancing age, and the use of antihypertensives showed a similar pattern. LDL-C levels were highest among individuals aged 56–60 years; however, the use of lipid-lowering therapy increased with older age.

Scientists noted, “These findings highlight the critical role of cumulative exposure to these risk factors in an individual’s risk of CHD, indicating that past exposure to elevated SBP and LDL-C has long-lasting implications on future CHD risk.”

Journal Reference:

Wang N, Mustafa R, Zuber V, Rodgers A, Dehghan A (2023) Association between systolic blood pressure and low-density lipoprotein cholesterol with coronary heart disease according to age. PLoS ONE 18(12): e0295004. DOI: 10.1371/journal.pone.0295004

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Tech Explorist – https://www.techexplorist.com/pre-55-high-cholesterol-blood-pressure-raise-lifelong-heart-disease-risk/79110/

Tags: bloodCholesterolscience
Previous Post

US: Indian-origin couple, teen daughter found dead inside $4 million mansion

Next Post

Each additional 1cm of waist measurement raises women’s infertility risk

Jason Anderson Signs for Suzuki for 2026 SMX World Championship – Monster Energy AMA Supercross

Jason Anderson Signs for Suzuki for 2026 SMX World Championship – Monster Energy AMA Supercross

October 7, 2025
Downtown St. Paul’s economy showing new life after state employees mandated to return to office – 5 EYEWITNESS NEWS

Downtown St. Paul Thrives Again as State Employees Return to the Office

October 7, 2025
No, Anthony Boyle Didn’t Use a Prosthetic in His House of Guinness Bath Scene – Yahoo

Anthony Boyle Opens Up About the Shocking Truth Behind His House of Gucci Bath Scene

October 7, 2025
Ozzy Osbourne documentary reveals agonizing health struggles of his final years – USA Today

Inside Ozzy Osbourne’s Heartbreaking Battle with Health in His Final Years

October 7, 2025
Latino leaders explore the role community organizing can play in national politics – OSV News

Latino Leaders Unite to Amplify Community Power and Drive National Change

October 7, 2025
Ecology blazing the trail for more clean energy projects – Washington State Department of Ecology (.gov)

How Ecology is Powering the Shift to a Greener Energy Future

October 7, 2025
Penn State Brandywine Earth sciences professor earns two national awards – Penn State University

Penn State Brandywine Earth sciences professor earns two national awards – Penn State University

October 7, 2025
UNESCO and CODATA launch resources on open science for crisis response – unesco.org

UNESCO and CODATA Launch Innovative Open Science Tools to Enhance Crisis Response

October 7, 2025
New Engen Report Identifies Key Trends and Winning Strategies for Active Lifestyle Brands in 2025 and Beyond – Fitt Insider

New Engen Report Identifies Key Trends and Winning Strategies for Active Lifestyle Brands in 2025 and Beyond – Fitt Insider

October 7, 2025
ARM Institute opens technology project call to speed submarine manufacturing – The Robot Report

ARM Institute Unveils Cutting-Edge Technology Project to Revolutionize Submarine Manufacturing

October 7, 2025

Categories

Archives

October 2025
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (855)
  • Economy (876)
  • Entertainment (21,749)
  • General (17,457)
  • Health (9,918)
  • Lifestyle (888)
  • News (22,149)
  • People (877)
  • Politics (887)
  • Science (16,086)
  • Sports (21,376)
  • Technology (15,856)
  • World (859)

Recent News

Jason Anderson Signs for Suzuki for 2026 SMX World Championship – Monster Energy AMA Supercross

Jason Anderson Signs for Suzuki for 2026 SMX World Championship – Monster Energy AMA Supercross

October 7, 2025
Downtown St. Paul’s economy showing new life after state employees mandated to return to office – 5 EYEWITNESS NEWS

Downtown St. Paul Thrives Again as State Employees Return to the Office

October 7, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version