* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Tuesday, October 28, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    What to Know About ‘Good Morning America’s 50th Anniversary Episode – Wyoming News Now

    Celebrate the Milestone: Everything You Need to Know About Good Morning America’s 50th Anniversary Episode

    Dylan Efron suffers brutal nose injury in ‘DWTS’ rehearsals – Yahoo

    Dylan Efron Endures Painful Nose Injury During ‘DWTS’ Rehearsals

    Person shot, injured in parking lot of adult entertainment club in Gresham – KPTV

    Person Shot and Injured in Gresham Adult Entertainment Club Parking Lot

    Meet Belynda From ‘Married at First Sight’ Season 19: Age, Job, Instagram and More – Yahoo

    Meet Belynda from ‘Married at First Sight’ Season 19: Age, Career, Instagram & More Revealed!

    General Hospital’s Rena Sofer Exits as Lois — But the Door Isn’t Closed – Yahoo

    General Hospital’s Rena Sofer Exits as Lois — But the Door Isn’t Closed – Yahoo

    CNN Launches New Show – What to Know About Host Elex Michaelson – Central Oregon Daily

    Get to Know Elex Michaelson: The Dynamic New Host Taking CNN by Storm

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

    CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

    Researchers Discover New Bacterium That Turns Food Waste Into Energy – Technology Networks

    Scientists Unveil Breakthrough Bacterium That Transforms Food Waste Into Clean Energy

    Jim Cramer on GSI Technology: “That Thing is a Rocket Ship” – Yahoo Finance

    Jim Cramer Labels GSI Technology a “Rocket Ship” Poised for Takeoff

    The Anti-Tech Backlash Is Going to Grow Stronger – Jacobin

    The Anti-Tech Backlash Is Gaining Unstoppable Momentum

    Comments to EU Regarding the Draft Revised Technology Transfer Block Exemption Regulation and Technology Transfer Guidelines – Information Technology and Innovation Foundation

    Have Your Say: Share Your Thoughts on the Draft Revised Technology Transfer Block Exemption Regulation and Guidelines

    Ghost Tapping is exploiting tap-to-pay technology in order to steal your money; what your need to know – ABC7 New York

    Ghost Tapping: How Thieves Are Using Tap-to-Pay Technology to Steal Your Money and What You Need to Know

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    What to Know About ‘Good Morning America’s 50th Anniversary Episode – Wyoming News Now

    Celebrate the Milestone: Everything You Need to Know About Good Morning America’s 50th Anniversary Episode

    Dylan Efron suffers brutal nose injury in ‘DWTS’ rehearsals – Yahoo

    Dylan Efron Endures Painful Nose Injury During ‘DWTS’ Rehearsals

    Person shot, injured in parking lot of adult entertainment club in Gresham – KPTV

    Person Shot and Injured in Gresham Adult Entertainment Club Parking Lot

    Meet Belynda From ‘Married at First Sight’ Season 19: Age, Job, Instagram and More – Yahoo

    Meet Belynda from ‘Married at First Sight’ Season 19: Age, Career, Instagram & More Revealed!

    General Hospital’s Rena Sofer Exits as Lois — But the Door Isn’t Closed – Yahoo

    General Hospital’s Rena Sofer Exits as Lois — But the Door Isn’t Closed – Yahoo

    CNN Launches New Show – What to Know About Host Elex Michaelson – Central Oregon Daily

    Get to Know Elex Michaelson: The Dynamic New Host Taking CNN by Storm

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

    CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

    Researchers Discover New Bacterium That Turns Food Waste Into Energy – Technology Networks

    Scientists Unveil Breakthrough Bacterium That Transforms Food Waste Into Clean Energy

    Jim Cramer on GSI Technology: “That Thing is a Rocket Ship” – Yahoo Finance

    Jim Cramer Labels GSI Technology a “Rocket Ship” Poised for Takeoff

    The Anti-Tech Backlash Is Going to Grow Stronger – Jacobin

    The Anti-Tech Backlash Is Gaining Unstoppable Momentum

    Comments to EU Regarding the Draft Revised Technology Transfer Block Exemption Regulation and Technology Transfer Guidelines – Information Technology and Innovation Foundation

    Have Your Say: Share Your Thoughts on the Draft Revised Technology Transfer Block Exemption Regulation and Guidelines

    Ghost Tapping is exploiting tap-to-pay technology in order to steal your money; what your need to know – ABC7 New York

    Ghost Tapping: How Thieves Are Using Tap-to-Pay Technology to Steal Your Money and What You Need to Know

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Menopausal Hormone Changes Linked to Cognitive Deficits

November 29, 2023
in Science
Menopausal Hormone Changes Linked to Cognitive Deficits
Share on FacebookShare on Twitter

Exhausted Woman Brain Fog

New research links menopause to cognitive deficits and brain atrophy, emphasizing the role of estrogen receptor beta in astrocytes. Findings from female mice studies suggest potential treatments targeting ERβ for improving cognition and reversing brain changes in menopause.

A recent study led by Dr. Rhonda Voskuhl, a neurologist at UCLA, has unveiled significant insights into how menopause contributes to cognitive decline and brain shrinkage, pinpointing the vital influence of estrogen receptor beta (ERβ) in astrocytes.

This research, carried out using female mice, identified the specific brain regions and mechanisms that drive the cognitive alterations observed during menopause.

Estrogen Loss and Cognitive Impairment: Insights from Animal Models

The research found that loss of ovarian hormones in female mice during midlife, but not at a younger age, induced cognitive impairment. This revealed that both aging and loss of estrogen were critical to cognitive deficits.

Additionally, brain MRIs of these midlife female mice demonstrated atrophy of the dorsal hippocampus, a brain region central to memory and learning, and pathology revealed activation of astrocytes and microglia, with synaptic loss.

The Role of Estrogen Receptor Beta in Brain Health

Selective deletion of estrogen receptor beta (ERβ) in astrocytes, a supportive brain cell, had the same detrimental effects on the brain as hormone loss, suggesting that ERβ in astrocytes plays a pivotal role in maintaining hippocampal function during menopause.

To translate their findings to humans, the researchers showed that changes in gene expression in the hippocampus of estrogen-deficient midlife female mice involved abnormal glucose utilization, and expression of a key gene in this pathway also occurred in post-menopausal women.

Potential Treatments for Menopause-Induced Brain Changes

Aiming to prevent the deleterious effects of estrogen deficiency at midlife, mice treated with an ERβ ligand had improved cognition and reversal of the neuropathological changes observed in the dorsal hippocampus.

While further research is needed to translate these findings into clinical applications for human patients, the study marks a significant step toward understanding the brain’s response to hormonal changes during menopause and offers hope for potential treatments in the future. 

Reference: “Estrogen receptor beta in astrocytes modulates cognitive function in mid-age female mice” by Noriko Itoh, Yuichiro Itoh, Cassandra E. Meyer, Timothy Takazo Suen, Diego Cortez-Delgado, Michelle Rivera Lomeli, Sophia Wendin, Sri Sanjana Somepalli, Lisa C. Golden, Allan MacKenzie-Graham and Rhonda R. Voskuhl, 28 September 2023, Nature Communications.
DOI: 10.1038/s41467-023-41723-7

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : SciTechDaily – https://scitechdaily.com/menopausal-hormone-changes-linked-to-cognitive-deficits/

Tags: HormoneMenopausalscience
Previous Post

Rwanda migrant bill set to rise again as Rishi Sunak reveals judges will not block flights

Next Post

The Pancreatic Puzzle: Cracking the Code of Cancer’s Immune Secrets

Once tadpoles lose lungs, they never get them back – Cornell Chronicle

October 28, 2025
Texas A&M Department of Poultry Science hires Williams – WATTPoultry.com

Texas A&M’s Poultry Science Department Welcomes Expert Williams to the Team

October 28, 2025

Raffaele Colombo Highlights the Thriving Community and Cutting-Edge Science at the Incredible AACR-NCI-EORTC Meeting

October 28, 2025
The Donut Chain Known For Making Some Of The Most Unique Flavors In The Game – Yahoo

Discover the Donut Chain Revolutionizing Flavor with Its Uniquely Delicious Creations

October 28, 2025
CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

CPE Technology Berhad (KLSE:CPETECH) Has Affirmed Its Dividend Of MYR0.015 – Yahoo Finance

October 28, 2025
Clippers fans chant “F-B-I” at Blazers players while shooting free throws during Sunday’s game – Yahoo Sports

Clippers Fans Erupt with “F-B-I” Chants at Blazers Players During Sunday’s Intense Showdown

October 28, 2025
Enter the world of the Pirates of Emerson… if you dare! – NBC4 Los Angeles

Enter the world of the Pirates of Emerson… if you dare! – NBC4 Los Angeles

October 27, 2025
Seneca Nation drives nearly $2B impact on Western New York economy – ReadWrite

Seneca Nation Ignites Nearly $2 Billion Economic Surge in Western New York

October 27, 2025
What to Know About ‘Good Morning America’s 50th Anniversary Episode – Wyoming News Now

Celebrate the Milestone: Everything You Need to Know About Good Morning America’s 50th Anniversary Episode

October 27, 2025
Shingles vaccine connected to ‘exciting’ health benefits in large study – Fox News

Shingles vaccine connected to ‘exciting’ health benefits in large study – Fox News

October 27, 2025

Categories

Archives

October 2025
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (889)
  • Economy (911)
  • Entertainment (21,782)
  • General (17,845)
  • Health (9,952)
  • Lifestyle (924)
  • News (22,149)
  • People (912)
  • Politics (921)
  • Science (16,122)
  • Sports (21,411)
  • Technology (15,891)
  • World (894)

Recent News

Once tadpoles lose lungs, they never get them back – Cornell Chronicle

October 28, 2025
Texas A&M Department of Poultry Science hires Williams – WATTPoultry.com

Texas A&M’s Poultry Science Department Welcomes Expert Williams to the Team

October 28, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version