* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Tuesday, September 2, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

    Country music star apologizes after drunken show ends with cops taking him down: ‘I’m not OK’ – PennLive.com

    Country Music Star Apologizes After Drunken Show Ends in Police Intervention: ‘I’m Not OK

    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

    Erykah Badu Announces ‘Abi & Alan’ Album With The Alchemist Will Be Delayed – yahoo.com

    Erykah Badu Opens Up About the Delay of Her Highly Anticipated ‘Abi & Alan’ Album with The Alchemist

    If You Needed Some BTS Pics Of The Rock’s Tree Trunk Legs To Spice Up Your Day, We Got ‘Em – yahoo.com

    Need a Boost? Check Out These Epic BTS Shots of The Rock’s Tree Trunk Legs!

    Sabrina Carpenter’s pearl-clutching magic? Humor – CNN

    Sabrina Carpenter’s pearl-clutching magic? Humor – CNN

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    China’s CATL sells stake in Finnish subcontract car manufacturer – Reuters

    China’s CATL Sells Stake in Finnish Auto Supplier in Strategic Move

    This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

    How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

    Gator football kicks off with excitement and new technology – WCJB | TV20

    Gator Football Kicks Off with Thrilling Action and Innovative Technology

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Propelling solar technology into a perovskite future – CORDIS

    Propelling solar technology into a perovskite future – CORDIS

    13 Top Technology Trends (2025) – Exploding Topics

    13 Game-Changing Technology Trends to Watch in 2025

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

    Country music star apologizes after drunken show ends with cops taking him down: ‘I’m not OK’ – PennLive.com

    Country Music Star Apologizes After Drunken Show Ends in Police Intervention: ‘I’m Not OK

    Comanche Nation Entertainment closes casino near Devol – KSWO 7News

    Comanche Nation Entertainment Closes Casino Near Devol in Surprising Move

    Erykah Badu Announces ‘Abi & Alan’ Album With The Alchemist Will Be Delayed – yahoo.com

    Erykah Badu Opens Up About the Delay of Her Highly Anticipated ‘Abi & Alan’ Album with The Alchemist

    If You Needed Some BTS Pics Of The Rock’s Tree Trunk Legs To Spice Up Your Day, We Got ‘Em – yahoo.com

    Need a Boost? Check Out These Epic BTS Shots of The Rock’s Tree Trunk Legs!

    Sabrina Carpenter’s pearl-clutching magic? Humor – CNN

    Sabrina Carpenter’s pearl-clutching magic? Humor – CNN

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    China’s CATL sells stake in Finnish subcontract car manufacturer – Reuters

    China’s CATL Sells Stake in Finnish Auto Supplier in Strategic Move

    This Secret Technology Will Make The IPhone 17 Super Thin Air – VOI.ID

    How This Breakthrough Technology Will Make the iPhone 17 Incredibly Thin and Lightweight

    Gator football kicks off with excitement and new technology – WCJB | TV20

    Gator Football Kicks Off with Thrilling Action and Innovative Technology

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Marvell Technology (MRVL) Loses 18.6% as Growth Outlook Fails to Impress – Yahoo Finance

    Propelling solar technology into a perovskite future – CORDIS

    Propelling solar technology into a perovskite future – CORDIS

    13 Top Technology Trends (2025) – Exploding Topics

    13 Game-Changing Technology Trends to Watch in 2025

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Multi-electrode integration in gut-on-chip systems enhances intestinal barrier monitoring

May 29, 2024
in Science
Multi-electrode integration in gut-on-chip systems enhances intestinal barrier monitoring
Share on FacebookShare on Twitter

A leap forward in gut health research: Multi-electrode integration in gut-on-chip systems

Credit: Microsystems & Nanoengineering (2024). DOI: 10.1038/s41378-023-00640-x

To enhance the fields of drug development and medical research, there has been a strategic pivot from traditional animal experiments to the adoption of novel in vitro models. These models meticulously replicate human physiology, spurring the development of microphysiological systems or Organs-on-Chips.

This evolution presents a more ethical and sophisticated framework for investigating human organs and diseases, accurately simulating organ functions and enabling detailed studies of tissue and organ health without the moral quandaries associated with animal testing. Specifically, the gut-on-a-chip model emerges as a cutting-edge tool for investigating the intestinal barrier’s reaction to a myriad of factors, utilizing advanced techniques like transepithelial electrical resistance (TEER) for the real-time assessment of barrier integrity.

Published on January 24, 2024, in Microsystems & Nanoengineering, a study showcases a method to enhance intestinal barrier monitoring within the Human Microbial Crosstalk (HuMiX) gut-on-a-chip model.

This method facilitates real-time, spatially resolved measurements of TEER, offering direct insights into the gut barrier’s integrity. By overcoming the limitations of previous designs, the research team introduced a novel fabrication process that applies thin-film metal electrodes onto flexible substrates, which are then seamlessly incorporated into the HuMiX platform via a transfer-tape method.

This innovative setup allows for comprehensive monitoring of barrier formation, disruption, and recovery, detailing the cell culture area’s different sections. The strategic placement of electrodes navigates the platform’s intricate design, ensuring accurate and reliable data collection. The application of impedance spectroscopy enhances this data, enabling measurements across various frequencies.

Demonstrating the system’s efficacy, the researchers conducted real-time monitoring of a cancerous epithelial cell line’s barrier formation, underscoring the model’s potential to shed light on gut health and disease pathways.

Researchers from the University of Luxembourg and the University of Uppsala collaborated on this study and underscore the significance of this advancement, “This technology significantly advances our capability to monitor the gut barrier function in real-time, offering insights into the complex interactions between gut epithelial cells and the microbiome. This marks a considerable leap towards the realization of personalized medicine and the formulation of targeted interventions for gut-related conditions.”

This novel method of monitoring the formation and integrity of the gut barrier heralds a new era in gut health research. It profoundly influences our comprehension of the gut barrier’s reaction to various stimuli, paving the way for the innovation of therapeutic approaches for gut-related diseases. Moreover, its implications for personalized medicine are profound, enabling precise predictions of individual reactions to dietary adjustments or medical treatments.

More information:
Mara Lucchetti et al, Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system, Microsystems & Nanoengineering (2024). DOI: 10.1038/s41378-023-00640-x

Provided by
TranSpread

Citation:
Multi-electrode integration in gut-on-chip systems enhances intestinal barrier monitoring (2024, May 29)
retrieved 29 May 2024
from https://phys.org/news/2024-05-multi-electrode-gut-chip-intestinal.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Phys.org – https://phys.org/news/2024-05-multi-electrode-gut-chip-intestinal.html

Tags: integrationMulti-electrodescience
Previous Post

Theory of everything: How a fear of failure is hampering physicists’ quest for the ultimate answer

Next Post

New technique offers more precise maps of the moon’s surface

Russia and China redouble their efforts to reshape the world order – CNN

Russia and China redouble their efforts to reshape the world order – CNN

September 2, 2025
How Bad Bunny’s Puerto Rico Residency is Boosting the Economy – The New York Times

How Bad Bunny’s Puerto Rico Residency is Sparking a Local Economic Boom

September 2, 2025
Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

September 2, 2025
Trump quashes health concerns on Truth Social, ‘never felt better in my life’ and tees up next battle with Fed’s Lisa Cook – Fortune

Trump Denies Health Rumors, Says He’s ‘Never Felt Better’ as He Gears Up for Next Showdown with Fed’s Lisa Cook

September 2, 2025
The 1600: The Hell-Cycle of Political Prosecutions – Newsweek

The 1600: The Hell-Cycle of Political Prosecutions – Newsweek

September 2, 2025
Construction of forest ecological security patterns based on MSPA model and circuit theory in the Desertification Control forests in South China Karst – Nature

Construction of forest ecological security patterns based on MSPA model and circuit theory in the Desertification Control forests in South China Karst – Nature

September 2, 2025
Bringing life science to life: Park Crossing teacher recognized – WSFA

Bringing life science to life: Park Crossing teacher recognized – WSFA

September 2, 2025
Take flight: EH seventh-graders learn science through paper airplanes – The Daily Reporter – Greenfield Indiana

Soar to New Heights: Seventh-Graders Explore Science with Paper Airplanes

September 2, 2025
Marcos orders lifestyle audit of all government officials — Dateline Philippines – Asian Journal News

Marcos Initiates Comprehensive Lifestyle Audit of Government Officials to Boost Accountability

September 2, 2025
China’s CATL sells stake in Finnish subcontract car manufacturer – Reuters

China’s CATL Sells Stake in Finnish Auto Supplier in Strategic Move

September 2, 2025

Categories

Archives

September 2025
MTWTFSS
1234567
891011121314
15161718192021
22232425262728
2930 
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (802)
  • Economy (821)
  • Entertainment (21,701)
  • General (16,809)
  • Health (9,862)
  • Lifestyle (835)
  • News (22,149)
  • People (822)
  • Politics (829)
  • Science (16,031)
  • Sports (21,319)
  • Technology (15,801)
  • World (802)

Recent News

Russia and China redouble their efforts to reshape the world order – CNN

Russia and China redouble their efforts to reshape the world order – CNN

September 2, 2025
How Bad Bunny’s Puerto Rico Residency is Boosting the Economy – The New York Times

How Bad Bunny’s Puerto Rico Residency is Sparking a Local Economic Boom

September 2, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version