* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Sunday, September 7, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Victor Garber on his viral “And Just Like That” toilet scene: ‘I was delighted to be doing something ridiculous’ (exclusive) – yahoo.com

    Victor Garber on his viral “And Just Like That” toilet scene: ‘I was delighted to be doing something ridiculous’ (exclusive) – yahoo.com

    Pendulum Announce Homecoming 2026 Australian Tour – yahoo.com

    Pendulum Announces Thrilling Homecoming Tour Across Australia in 2026

    ITV Studios Launches New Entertainment Label – Global Bulletin – IMDb

    ITV Studios Unveils Exciting New Entertainment Label

    TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

    TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

    Jenny Han Dropped a Major ‘The Summer I Turned Pretty’ Easter Egg Revealing [SPOILER] – yahoo.com

    Jenny Han Just Unveiled a Huge ‘The Summer I Turned Pretty’ Easter Egg That Changes Everything [SPOILER]

    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Health Technology Ecosystem – Centers for Medicare & Medicaid Services | CMS (.gov)

    Discover the Future of Health Technology: Innovations Revolutionizing Patient Care

    Coherent Joins LLNL’s STARFIRE Diode Technology Working Group to Advance Inertial Fusion Energy – GlobeNewswire

    Coherent Partners with LLNL’s STARFIRE Team to Drive Breakthroughs in Inertial Fusion Energy

    Gene Associated With Deadly Heart Disease in Golden Retrievers Identified – Technology Networks

    Breakthrough Discovery Uncovers Gene Behind Deadly Heart Disease in Golden Retrievers

    Monkey Island LNG Picks ConocoPhillips’ Liquefaction Technology – Hart Energy

    Monkey Island LNG Selects ConocoPhillips’ Advanced Liquefaction Technology for Next-Gen Energy Solutions

    Credo Technology Group Holding Ltd. (CRDO) Surpasses Q1 Earnings and Revenue Estimates – Yahoo Finance

    Credo Technology Group Surpasses Q1 Earnings and Revenue Expectations

    The Economist is hiring a science and technology correspondent – The Economist

    Exciting Opportunity: Become Our Next Science and Technology Correspondent!

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Victor Garber on his viral “And Just Like That” toilet scene: ‘I was delighted to be doing something ridiculous’ (exclusive) – yahoo.com

    Victor Garber on his viral “And Just Like That” toilet scene: ‘I was delighted to be doing something ridiculous’ (exclusive) – yahoo.com

    Pendulum Announce Homecoming 2026 Australian Tour – yahoo.com

    Pendulum Announces Thrilling Homecoming Tour Across Australia in 2026

    ITV Studios Launches New Entertainment Label – Global Bulletin – IMDb

    ITV Studios Unveils Exciting New Entertainment Label

    TS Entertainment bringing Malibu Jack’s to former Owensboro mall – Lane Report

    TS Entertainment Launches Malibu Jack’s at Former Owensboro Mall Location

    Jenny Han Dropped a Major ‘The Summer I Turned Pretty’ Easter Egg Revealing [SPOILER] – yahoo.com

    Jenny Han Just Unveiled a Huge ‘The Summer I Turned Pretty’ Easter Egg That Changes Everything [SPOILER]

    Liam Payne’s Cousin Ross Harris Honors Late Singer With Emotional Song ‘Bones’ – yahoo.com

    Liam Payne’s Cousin Ross Harris Honors Late Singer with Emotional New Song ‘Bones

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Health Technology Ecosystem – Centers for Medicare & Medicaid Services | CMS (.gov)

    Discover the Future of Health Technology: Innovations Revolutionizing Patient Care

    Coherent Joins LLNL’s STARFIRE Diode Technology Working Group to Advance Inertial Fusion Energy – GlobeNewswire

    Coherent Partners with LLNL’s STARFIRE Team to Drive Breakthroughs in Inertial Fusion Energy

    Gene Associated With Deadly Heart Disease in Golden Retrievers Identified – Technology Networks

    Breakthrough Discovery Uncovers Gene Behind Deadly Heart Disease in Golden Retrievers

    Monkey Island LNG Picks ConocoPhillips’ Liquefaction Technology – Hart Energy

    Monkey Island LNG Selects ConocoPhillips’ Advanced Liquefaction Technology for Next-Gen Energy Solutions

    Credo Technology Group Holding Ltd. (CRDO) Surpasses Q1 Earnings and Revenue Estimates – Yahoo Finance

    Credo Technology Group Surpasses Q1 Earnings and Revenue Expectations

    The Economist is hiring a science and technology correspondent – The Economist

    Exciting Opportunity: Become Our Next Science and Technology Correspondent!

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

New Potential Obesity Treatment Discovered: Hidden Brain Receptor May Hold Key to Controlling Your Appetite

July 25, 2024
in Science
New Potential Obesity Treatment Discovered: Hidden Brain Receptor May Hold Key to Controlling Your Appetite
Share on FacebookShare on Twitter

Potential Treatment for Obesity

Recent research identifies the latrophilin 1 receptor as a potential regulator of eating behavior, suggesting new approaches to treating obesity by targeting this receptor.

A new potential approach to treating obesity has been identified.

The rising prevalence of overweight and obesity is a significant global medical challenge. Alongside lifestyle changes, genetic factors play a crucial role in the development of obesity. Researchers at Leipzig University and Heinrich Heine University Düsseldorf have identified a new regulator of eating behavior. The findings have been published in the internationally renowned Nature journal Signal Transduction and Targeted Therapy.

“Our research underscores our incomplete understanding of the factors governing food intake. It also reveals the potential involvement of previously overlooked receptors,” says Dr Doreen Thor, lead author of the study and scientist at the Faculty of Medicine at Leipzig University. The newly identified receptor, latrophilin 1, has primarily been studied for its functions in the brain such as synapse formation and development, but not for its role in controlling food intake. It is a G protein-coupled receptor and was so named because of its ability to bind to the neurotoxin latrotoxin. This toxin is produced by some spiders, including the Mediterranean black widow, and has the latrophilin 1 receptor as a key neuronal target structure.

Microscopic View of a Hypothalamus Brain Section

Microscopic view of a hypothalamus brain section. The third ventricle (black) is visible. The red dots show the receptor. The nuclei are blue. Credit: Leipzig University (Albert Ricken)

Impact on Eating Behavior and Physical Activity

In their studies, the research teams led by Dr. Thor from Leipzig University and Professor Simone Prömel from Heinrich Heine University Düsseldorf show that the latrophilin 1 receptor is present in the regions of the brain that control eating behaviour as well as in adipose tissue. In the study, mice lacking the receptor showed increased food intake and reduced physical activity. Although the juveniles were initially of normal weight, they became significantly overweight over the course of a further four months. This in turn leads to the well-known comorbidities of obesity, such as fatty liver and diabetes mellitus.

In addition, the researchers identified a receptor variant of latrophilin 1 in the sequencing data from the Leipzig obesity cohort that occurred in one patient with overweight. Cell culture studies indicated this variant’s impaired functionality, suggesting that the receptor may play a role in the development of obesity not only in animal models, but also in humans.

“The results provide a new approach to understanding the regulation of food intake and the development of obesity,” says Professor Simone Prömel, another corresponding author of the paper. Future studies in the participating research groups at the universities in Leipzig and Düsseldorf will now clarify whether the receptor can serve as a potential pharmacological target for the regulation of food intake in obesity.

Reference: “Dysfunction of the adhesion G protein-coupled receptor latrophilin 1 (ADGRL1/LPHN1) increases the risk of obesity” by André Nguyen Dietzsch, Hadi Al-Hasani, Joachim Altschmied, Katharina Bottermann, Jana Brendler, Judith Haendeler, Susanne Horn, Isabell Kaczmarek, Antje Körner, Kerstin Krause, Kathrin Landgraf, Diana Le Duc, Laura Lehmann, Stefan Lehr, Stephanie Pick, Albert Ricken, Rene Schnorr, Angela Schulz, Martina Strnadová, Akhil Velluva, Heba Zabri, Torsten Schöneberg, Doreen Thor and Simone Prömel, 26 April 2024, Signal Transduction and Targeted Therapy.
DOI: 10.1038/s41392-024-01810-7

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : SciTechDaily – https://scitechdaily.com/new-potential-obesity-treatment-discovered-hidden-brain-receptor-may-hold-key-to-controlling-your-appetite/

Tags: ObesityPotentialscience
Previous Post

Webb Space Telescope Unveils the Strange Split Personality of WASP-39b

Next Post

Baby teeth reveal surprisingly long lifespans of small Jurassic mammals

This Week in Science: Out-of-Sync Seasons, Anti-Aging Breakthroughs, And More! – yahoo.com

This Week in Science: Out-of-Sync Seasons, Anti-Aging Breakthroughs, And More! – yahoo.com

September 7, 2025
Diagnostic dilemma: Woman’s severe knee pain reveals ‘golden threads’ in her joints – Live Science

Mystery Solved: Woman’s Severe Knee Pain Traced to Shimmering ‘Golden Threads’ in Her Joints

September 7, 2025
PHOTOS: All the celebrities at Aryna Sabalenka’s US Open final victory – Tennis.com

PHOTOS: All the celebrities at Aryna Sabalenka’s US Open final victory – Tennis.com

September 7, 2025
Health Technology Ecosystem – Centers for Medicare & Medicaid Services | CMS (.gov)

Discover the Future of Health Technology: Innovations Revolutionizing Patient Care

September 7, 2025
Vermont H.S. sports scores for Friday, Sept. 5: See how your favorite team fared – Burlington Free Press

Friday Night Showdowns: Vermont High School Sports Scores and Highlights from Sept. 5

September 7, 2025
Reformulation of general relativity brings it closer to Newtonian physics – Physics World

Reformulation of general relativity brings it closer to Newtonian physics – Physics World

September 7, 2025
Trump’s Economy Fails Arkansans as Unemployment Reaches Four-Year High – SWARK Today

Trump’s Economy Fails Arkansans as Unemployment Reaches Four-Year High – SWARK Today

September 7, 2025
Victor Garber on his viral “And Just Like That” toilet scene: ‘I was delighted to be doing something ridiculous’ (exclusive) – yahoo.com

Victor Garber on his viral “And Just Like That” toilet scene: ‘I was delighted to be doing something ridiculous’ (exclusive) – yahoo.com

September 7, 2025
Heroes on the Hill event addresses mental health for vets, first responders – CBS News

Heroes on the Hill: Tackling Mental Health Challenges for Vets and First Responders

September 7, 2025

Trump signs executive order creating ‘state sponsor of wrongful detention’ designation – CNN

September 7, 2025

Categories

Archives

September 2025
MTWTFSS
1234567
891011121314
15161718192021
22232425262728
2930 
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (810)
  • Economy (829)
  • Entertainment (21,706)
  • General (16,898)
  • Health (9,870)
  • Lifestyle (842)
  • News (22,149)
  • People (831)
  • Politics (835)
  • Science (16,039)
  • Sports (21,328)
  • Technology (15,809)
  • World (810)

Recent News

This Week in Science: Out-of-Sync Seasons, Anti-Aging Breakthroughs, And More! – yahoo.com

This Week in Science: Out-of-Sync Seasons, Anti-Aging Breakthroughs, And More! – yahoo.com

September 7, 2025
Diagnostic dilemma: Woman’s severe knee pain reveals ‘golden threads’ in her joints – Live Science

Mystery Solved: Woman’s Severe Knee Pain Traced to Shimmering ‘Golden Threads’ in Her Joints

September 7, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version