* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Tuesday, September 16, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    The Emmys are back: Viewership soars to highest numbers in 4 years – yahoo.com

    The Emmys Return with a Bang: Viewership Hits a 4-Year High

    From Spinal Tap II to Ed Sheeran : your complete entertainment guide to the week ahead – The Guardian

    Fall’s Hottest Ski Films Are Going on Tour—Here’s the List – yahoo.com

    Experience the Thrill: Fall’s Hottest Ski Films Hit the Road-Don’t Miss the Tour!

    Ryan Reynolds reveals he called a journalist who said mean things about John Candy – yahoo.com

    Ryan Reynolds Reveals the Moment He Stood Up to a Journalist Who Insulted John Candy

    Entertainment Community Fund Launches Program Supporting Entrepreneurs – Playbill

    Entertainment Community Fund Unveils Exciting New Program to Empower Entrepreneurs

    Behind the turntables: DJ Johnny Kage’s story of perseverance – yahoo.com

    Behind the Turntables: DJ Johnny Kage’s Inspiring Journey of Perseverance

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Will New Big Technology Engagements Reshape Innodata’s Growth Path? – Yahoo Finance

    Could New Major Tech Partnerships Propel Innodata to Unprecedented Growth?

    Unlocking AI Success: How People, Process, and Technology Form the Ultimate Triangle

    Billion-dollar coffins? New technology could make oceans transparent and Aukus submarines vulnerable – The Guardian

    Billion-Dollar Coffins? How New Technology Could Make Oceans Transparent and Expose Submarines

    What if artificial intelligence is just a “normal” technology? – The Economist

    What if artificial intelligence is just a “normal” technology? – The Economist

    Lincoln Trail College Receives $100,000 Grant from Marathon Petroleum Corporation for Technology Center – wwbl.com

    Lincoln Trail College Lands $100,000 Grant from Marathon Petroleum to Elevate Technology Center

    Aston Martin to integrate Pirelli’s cyber tyre technology in future models – Just Auto

    Aston Martin to Revolutionize Future Models with Pirelli’s Cutting-Edge Cyber Tyre Technology

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    The Emmys are back: Viewership soars to highest numbers in 4 years – yahoo.com

    The Emmys Return with a Bang: Viewership Hits a 4-Year High

    From Spinal Tap II to Ed Sheeran : your complete entertainment guide to the week ahead – The Guardian

    Fall’s Hottest Ski Films Are Going on Tour—Here’s the List – yahoo.com

    Experience the Thrill: Fall’s Hottest Ski Films Hit the Road-Don’t Miss the Tour!

    Ryan Reynolds reveals he called a journalist who said mean things about John Candy – yahoo.com

    Ryan Reynolds Reveals the Moment He Stood Up to a Journalist Who Insulted John Candy

    Entertainment Community Fund Launches Program Supporting Entrepreneurs – Playbill

    Entertainment Community Fund Unveils Exciting New Program to Empower Entrepreneurs

    Behind the turntables: DJ Johnny Kage’s story of perseverance – yahoo.com

    Behind the Turntables: DJ Johnny Kage’s Inspiring Journey of Perseverance

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Will New Big Technology Engagements Reshape Innodata’s Growth Path? – Yahoo Finance

    Could New Major Tech Partnerships Propel Innodata to Unprecedented Growth?

    Unlocking AI Success: How People, Process, and Technology Form the Ultimate Triangle

    Billion-dollar coffins? New technology could make oceans transparent and Aukus submarines vulnerable – The Guardian

    Billion-Dollar Coffins? How New Technology Could Make Oceans Transparent and Expose Submarines

    What if artificial intelligence is just a “normal” technology? – The Economist

    What if artificial intelligence is just a “normal” technology? – The Economist

    Lincoln Trail College Receives $100,000 Grant from Marathon Petroleum Corporation for Technology Center – wwbl.com

    Lincoln Trail College Lands $100,000 Grant from Marathon Petroleum to Elevate Technology Center

    Aston Martin to integrate Pirelli’s cyber tyre technology in future models – Just Auto

    Aston Martin to Revolutionize Future Models with Pirelli’s Cutting-Edge Cyber Tyre Technology

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

New Study Links Gut Vitamin B Deficiency to Parkinson’s Disease

July 4, 2024
in Science
New Study Links Gut Vitamin B Deficiency to Parkinson’s Disease
Share on FacebookShare on Twitter

Parkinson’s Disease Vitamins B2 and B7 Graphic

In Parkinson’s disease, a reduction in the gut bacteria of genes responsible for synthesizing the essential B vitamins B2 and B7 was found. Credit: Reiko Matsushita

Nagoya University researchers found that deficiencies in gut bacteria genes for vitamins B2 and B7 are linked to Parkinson’s disease, suggesting that B vitamin supplementation could be a potential treatment.

A study conducted by the Nagoya University Graduate School of Medicine in Japan has discovered a connection between gut microbiota and Parkinson’s disease (PD). The researchers observed a decrease in gut bacteria genes responsible for synthesizing the essential B vitamins B2 and B7. Additionally, they found a link between the deficiency of these genes and reduced levels of agents that help preserve the integrity of the intestinal barrier.

This barrier prevents toxins from entering the bloodstream, which causes the inflammation seen in PD. Their findings, published in npj Parkinson’s Disease, suggest that treatment with B vitamins to address these deficiencies can be used to treat PD.

PD is characterized by a variety of physical symptoms that hinder daily activities and mobility, such as shaking, slow movement, stiffness, and balance problems. While the frequency of PD may vary between different populations, it is estimated to affect approximately 1-2% of individuals aged 55 years or older.

Various physiological processes are heavily influenced by the microorganisms found in the gut, which are collectively known as gut microbiota. In ideal conditions, gut microbiota produce SCFAs and polyamines, which maintain the intestinal barrier that prevents toxins from entering the bloodstream. Toxins in the blood can be carried to the brain where they cause inflammation and affect neurotransmission processes that are critical for maintaining mental health.

The Research Process

To better understand the relationship between the microbial characteristics of the gut in PD, Hiroshi Nishiwaki and Jun Ueyama from the Nagoya University Graduate School of Medicine conducted a metanalysis of stool samples from patients with PD from Japan, the United States, Germany, China, and Taiwan. They used shotgun sequencing, a technique that sequences all genetic material in a sample. This is an invaluable tool because it offers researchers a better understanding of the microbial community and genetic makeup of the sample.

They observed a decrease in the bacterial genes responsible for the synthesizing of riboflavin (vitamin B2) and biotin (vitamin B7) in patients diagnosed with PD. Riboflavin and biotin, derived from both food and gut microbiota, have anti-inflammatory properties, which may counteract the neuroinflammation seen in diseases like PD.

The Role of B Vitamins

B vitamins play crucial roles in the metabolic processes that influence the production and functions of short-chain fatty acids (SCFAs) and polyamines, two agents that help maintain the integrity of the intestinal barrier, preventing toxins from entering the bloodstream. An examination of fecal metabolites revealed decreases in both in patients with PD.

The findings indicate a potential explanation for the progression of PD. “Deficiencies in polyamines and SCFAs could lead to thinning of the intestinal mucus layer, increasing intestinal permeability, both of which have been observed in PD,” Nishiwaki explained. “This higher permeability exposes nerves to toxins, contributing to abnormal aggregation of alpha-synuclein, activating the immune cells in the brain, and leading to long-term inflammation.”

He added, “Supplementation therapy targeting riboflavin and biotin holds promise as a potential therapeutic avenue for alleviating PD symptoms and slowing disease progression.”

The results of the study highlight the importance of understanding the complex relationship among gut microbiota, metabolic pathways, and neurodegeneration. In the coming years, therapy could potentially be customized based on the unique microbiome profile of each patient. By altering bacterial levels in the microbiome, doctors can potentially delay the onset of symptoms associated with diseases like PD.

“We could perform gut microbiota analysis on patients or conduct fecal metabolite analysis,” Nishiwaki said. “Using these findings, we could identify individuals with specific deficiencies and administer oral riboflavin and biotin supplements to those with decreased levels, potentially creating an effective treatment.”

Reference: “Meta-analysis of shotgun sequencing of gut microbiota in Parkinson’s disease” by Hiroshi Nishiwaki, Jun Ueyama, Mikako Ito, Tomonari Hamaguchi, Keiichi Takimoto, Tetsuya Maeda, Kenichi Kashihara, Yoshio Tsuboi, Hiroshi Mori, Ken Kurokawa, Masahisa Katsuno, Masaaki Hirayama and Kinji Ohno, 21 May 2024, npj Parkinson’s Disease.
DOI: 10.1038/s41531-024-00724-z

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : SciTechDaily – https://scitechdaily.com/new-study-links-gut-vitamin-b-deficiency-to-parkinsons-disease/

Tags: Linkssciencestudy
Previous Post

10 Lesser-Known “First and Only” Facts about U.S. Presidents

Next Post

Unraveling Malaria’s Ancient Mysteries: DNA Reveals 5,500-Year-Old Infections

Antibiotic pollution could accelerate amphibian decline by turning a potential solution into a threat – Phys.org

Antibiotic pollution could accelerate amphibian decline by turning a potential solution into a threat – Phys.org

September 16, 2025
Fiji’s Ants Are Struggling. Scientists Say They’re Part of the Broader ‘Insect Apocalypse’ – Smithsonian Magazine

Fiji’s Ants Are Disappearing: A Stark Sign of the Global Insect Crisis

September 16, 2025

California Leads the Way with a Bipartisan, Science-Backed Ban on Ultra-Processed School Meals

September 16, 2025

Marwa Zaied: Leading the Revolution in Cancer Care and Longevity with Lifestyle Medicine

September 16, 2025
Will New Big Technology Engagements Reshape Innodata’s Growth Path? – Yahoo Finance

Could New Major Tech Partnerships Propel Innodata to Unprecedented Growth?

September 16, 2025
Registration open for fitness programs at Hereford Sports & Wellness – KFDA | NewsChannel 10

Registration open for fitness programs at Hereford Sports & Wellness – KFDA | NewsChannel 10

September 16, 2025
Men’s Freestyle Team Standings At The 2025 Senior World Championship – FloWrestling

Men’s Freestyle Team Standings at the 2025 Senior World Championship Revealed

September 15, 2025
ONEflight Myrtle Beach Classic boosts economy with $15.8M impact – WPDE

ONEflight Myrtle Beach Classic boosts economy with $15.8M impact – WPDE

September 15, 2025
The Emmys are back: Viewership soars to highest numbers in 4 years – yahoo.com

The Emmys Return with a Bang: Viewership Hits a 4-Year High

September 15, 2025
Bridging gap between artificial intelligence, real-world health outcomes – Rice University

Bridging the Divide: How Artificial Intelligence is Transforming Real-World Health Outcomes

September 15, 2025

Categories

Archives

September 2025
MTWTFSS
1234567
891011121314
15161718192021
22232425262728
2930 
« Aug    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (822)
  • Economy (841)
  • Entertainment (21,719)
  • General (17,059)
  • Health (9,885)
  • Lifestyle (856)
  • News (22,149)
  • People (845)
  • Politics (850)
  • Science (16,052)
  • Sports (21,341)
  • Technology (15,823)
  • World (824)

Recent News

Antibiotic pollution could accelerate amphibian decline by turning a potential solution into a threat – Phys.org

Antibiotic pollution could accelerate amphibian decline by turning a potential solution into a threat – Phys.org

September 16, 2025
Fiji’s Ants Are Struggling. Scientists Say They’re Part of the Broader ‘Insect Apocalypse’ – Smithsonian Magazine

Fiji’s Ants Are Disappearing: A Stark Sign of the Global Insect Crisis

September 16, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version