* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Saturday, October 18, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Elmira’s New Entertainment Venue ‘Centertown Social’ Adding its Final Touches – WENY News

    Elmira’s New Entertainment Venue ‘Centertown Social’ Adding its Final Touches – WENY News

    Bella Thorne Shows Off Her Toned Abs in Crop Top – Yahoo

    Bella Thorne Shows Off Her Toned Abs in a Chic Crop Top

    Bricktown continues to thrive as OKC’s entertainment district – OKC VeloCity

    Bricktown Shines as Oklahoma City’s Premier Entertainment Hotspot

    This Haunting ‘60s Country Song Is Even More Tragic Than You Remember – Yahoo

    This Haunting ’60s Country Song Will Break Your Heart All Over Again

    Arts/Entertainment: ‘Wait Until Dark’ brings spooky season center stage – Times Herald Online

    Wait Until Dark’ Delivers Chilling Thrills Perfect for the Spooky Season

    Bluesman James Montgomery Will Perform In Falmouth – CapeNews.net

    Blues Legend James Montgomery Ready to Ignite the Stage in Falmouth

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Guide to Proteomics Project Planning: Sample Preparation Strategies – Technology Networks

    Guide to Proteomics Project Planning: Sample Preparation Strategies – Technology Networks

    DLG−Agrifuture Concept Winners 2025 announced – Visionary Ideas in agricultural technology recognized – TheNewsMarket

    Meet the Visionary Innovators Revolutionizing Agricultural Technology in 2025

    Spanning the Gulf: Global Defence Technology 155 – Army Technology

    Spanning the Gulf: Exploring Cutting-Edge Global Defence Technology

    A Nobel Prize for explaining when technology leads to growth – NPR

    Nobel Prize Awarded for Unraveling How Technology Drives Economic Growth

    Erie Canal’s 200th anniversary: How a technological marvel for trade changed the environment forever – The Conversation

    Erie Canal’s 200th Anniversary: How a Trade Marvel Transformed the Environment Forever

    Day 5 of Gains Streak for Solidion Technology Stock with 475% Return (vs. -20% YTD) [10/14/2025] – Trefis

    Solidion Technology Stock Rockets for 5th Consecutive Day, Soaring an Astonishing 475% Year-to-Date

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Elmira’s New Entertainment Venue ‘Centertown Social’ Adding its Final Touches – WENY News

    Elmira’s New Entertainment Venue ‘Centertown Social’ Adding its Final Touches – WENY News

    Bella Thorne Shows Off Her Toned Abs in Crop Top – Yahoo

    Bella Thorne Shows Off Her Toned Abs in a Chic Crop Top

    Bricktown continues to thrive as OKC’s entertainment district – OKC VeloCity

    Bricktown Shines as Oklahoma City’s Premier Entertainment Hotspot

    This Haunting ‘60s Country Song Is Even More Tragic Than You Remember – Yahoo

    This Haunting ’60s Country Song Will Break Your Heart All Over Again

    Arts/Entertainment: ‘Wait Until Dark’ brings spooky season center stage – Times Herald Online

    Wait Until Dark’ Delivers Chilling Thrills Perfect for the Spooky Season

    Bluesman James Montgomery Will Perform In Falmouth – CapeNews.net

    Blues Legend James Montgomery Ready to Ignite the Stage in Falmouth

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Guide to Proteomics Project Planning: Sample Preparation Strategies – Technology Networks

    Guide to Proteomics Project Planning: Sample Preparation Strategies – Technology Networks

    DLG−Agrifuture Concept Winners 2025 announced – Visionary Ideas in agricultural technology recognized – TheNewsMarket

    Meet the Visionary Innovators Revolutionizing Agricultural Technology in 2025

    Spanning the Gulf: Global Defence Technology 155 – Army Technology

    Spanning the Gulf: Exploring Cutting-Edge Global Defence Technology

    A Nobel Prize for explaining when technology leads to growth – NPR

    Nobel Prize Awarded for Unraveling How Technology Drives Economic Growth

    Erie Canal’s 200th anniversary: How a technological marvel for trade changed the environment forever – The Conversation

    Erie Canal’s 200th Anniversary: How a Trade Marvel Transformed the Environment Forever

    Day 5 of Gains Streak for Solidion Technology Stock with 475% Return (vs. -20% YTD) [10/14/2025] – Trefis

    Solidion Technology Stock Rockets for 5th Consecutive Day, Soaring an Astonishing 475% Year-to-Date

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Promising breakthrough: Reversing autoimmune hair loss with novel treatment

May 9, 2024
in Science
Promising breakthrough: Reversing autoimmune hair loss with novel treatment
Share on FacebookShare on Twitter

Alopecia areata is an autoimmune disorder that causes hair loss and affects people of all ages, including children. There is no effective treatment for this type of hair loss.

Researchers at MIT, Brigham and Women’s Hospital, and Harvard Medical School have developed a potential new treatment that includes a microneedle patch that can be painlessly applied to the scalp and releases drugs that help to rebalance the immune response at the site, halting the autoimmune attack.

Scientists observed that while this treatment avoided systemic immunological responses elsewhere in the body, it allowed hair to regenerate and significantly reduced inflammation at the treatment site in a mouse trial. An adaptation of this approach could also treat other autoimmune skin conditions such as vitiligo, atopic dermatitis, and psoriasis.

Natalie Artzi, a principal research scientist in MIT’s Institute for Medical Engineering and Science, an associate professor of medicine at Harvard Medical School and Brigham and Women’s Hospital, and an assistant faculty member at the Wyss Institute of Harvard University said, “This innovative approach marks a paradigm shift. Rather than suppressing the immune system, we’re now focusing on regulating it precisely at the site of antigen encounter to generate immune tolerance.”

The study’s microneedle patches are composed of polyethylene glycol (PEG) and hyaluronic acid, both biocompatible and frequently utilized in medical applications. This technique allows medications to be delivered since creams administered topically cannot penetrate the epidermis’ protective outer layer.

Artzi said, “This polymer formulation allows us to create highly durable needles capable of effectively penetrating the skin. Additionally, it gives us the flexibility to incorporate any desired drug.”

The patches were loaded with a mixture of cytokines, CCL-22, and IL-2, specifically for this investigation. When these immunological chemicals work together, they can attract regulatory T cells, which multiply and reduce inflammation. Additionally, these cells teach the immune system to cease attacking hair follicles by teaching that they are not foreign antigens.

polyethylene glycol (PEG)The microneedle patches used in this study are made from hyaluronic acid crosslinked with polyethylene glycol (PEG), both of which are biocompatible and commonly used in medical applications. The researchers designed the microneedle patches so that after releasing their drug payload, they can also collect samples that could be used to monitor the progress of the treatment. Pictured is another microscopic view of the microneedles. Credit: MIT

According to the researchers, the mice administered this patch every other day for three weeks showed significantly reduced inflammation and a more significant number of regulatory T cells at the location. At such locations, hair could grow back, which persisted for a few weeks after the treatment. The fact that the regulatory T cell counts in these mice’s lymph nodes and spleen remained unchanged suggests that the treatment was limited to the area where the patch was placed.

In further trials, the scientists implanted human skin onto mice with immune systems tailored to humans. The administration of microneedles in these mice expanded regulatory T cells and decreased inflammation.

The purpose of the microneedle patches, according to the researchers, was to release the medication payload while simultaneously gathering samples that might be utilized to track the effectiveness of the treatment. After penetrating the skin, hyaluronic acid causes the needles to enlarge approximately ten times, enabling them to absorb interstitial fluid from the skin containing immunological cells and macromolecules.

Scientists can detect the numbers of regulatory T cells and inflammatory markers in samples by analyzing them after the patch is removed. This could be useful for monitoring patients who might receive this treatment in the future.

Journal References:

Nour Younis, Núria Puigmal, Abdallah El Kurdi et al. Microneedle-mediated Delivery of Immunomodulators Restores Immune Privilege in Hair Follicles and Reverses Immune-Mediated Alopecia. Advanced Materials. DOI: 10.1002/adma.202312088
Younis, Nour; Puigmal, Núria; Kurdi, Abdallah El; Badaoui, Andrew; Zhang, Dongliang. Microneedle‐mediated Delivery of Immunomodulators Restores Immune Privilege in Hair Follicles and Reverses Immune‐Mediated Alopecia. Advanced Materials. Paper.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Tech Explorist – https://www.techexplorist.com/promising-breakthrough-reversing-autoimmune-hair-loss-novel-treatment/83672/#utm_source=rss&utm_medium=rss&utm_campaign=promising-breakthrough-reversing-autoimmune-hair-loss-novel-treatment

Tags: BreakthroughPromisingscience
Previous Post

How do aging clocks tick?

Next Post

Chelsea close to £52m move for Brazilian as first deal of the summer: report

Harnessing the Full Potential of Large-Scale Diversification Dynamics

October 18, 2025
Georgia Southern to offer new Ph.D. in biomedical sciences – Statesboro Herald

Georgia Southern Unveils Groundbreaking New Ph.D. Program in Biomedical Sciences

October 18, 2025

Millburn Dominates Science Park in Exciting ECT Prelims Girls Soccer Clash

October 18, 2025
Cheetos Expected to Expand Flamin’ Hot Lineup With ‘Heavenly’ New Addition – Yahoo

Cheetos Expected to Expand Flamin’ Hot Lineup With ‘Heavenly’ New Addition – Yahoo

October 18, 2025
Guide to Proteomics Project Planning: Sample Preparation Strategies – Technology Networks

Guide to Proteomics Project Planning: Sample Preparation Strategies – Technology Networks

October 18, 2025
Alabama State Rallies Past Alabama A&M in Five-Set Thriller – Alabama State University Athletics

Alabama State Rallies Past Alabama A&M in Five-Set Thriller – Alabama State University Athletics

October 18, 2025
Iran Extends Internet Clampdown Beyond Wartime – The New York Times

Iran Intensifies Internet Crackdown, Extending Restrictions Well Beyond Wartime

October 17, 2025
US aims to raise $20bn ‘facility’ to support Argentina’s struggling economy – Al Jazeera

US Unveils $20 Billion Aid Package to Revitalize Argentina’s Economy

October 17, 2025
Elmira’s New Entertainment Venue ‘Centertown Social’ Adding its Final Touches – WENY News

Elmira’s New Entertainment Venue ‘Centertown Social’ Adding its Final Touches – WENY News

October 17, 2025
Respiratory syncytial virus (RSV) tied to heart problems – Harvard Health

New Study Reveals Surprising Connection Between RSV and Heart Complications

October 17, 2025

Categories

Archives

October 2025
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (873)
  • Economy (894)
  • Entertainment (21,766)
  • General (17,658)
  • Health (9,935)
  • Lifestyle (907)
  • News (22,149)
  • People (895)
  • Politics (904)
  • Science (16,105)
  • Sports (21,394)
  • Technology (15,874)
  • World (877)

Recent News

Harnessing the Full Potential of Large-Scale Diversification Dynamics

October 18, 2025
Georgia Southern to offer new Ph.D. in biomedical sciences – Statesboro Herald

Georgia Southern Unveils Groundbreaking New Ph.D. Program in Biomedical Sciences

October 18, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version