* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Sunday, June 29, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Susquehanna Raises Penn Entertainment Inc. (PENN) Price Target. – Yahoo Finance

    Susquehanna Raises Price Target for Penn Entertainment Inc. (PENN)

    George Lopez is coming to Spokane – KXLY.com

    George Lopez is coming to Spokane – KXLY.com

    Netflix unveils Dallas immersive venue for fans of hit shows like ‘Squid Game,’ ‘Stranger Things’ – Houston Chronicle

    Step Inside Netflix’s New Dallas Immersive Experience Featuring Hits Like ‘Squid Game’ and ‘Stranger Things

    ‘Puttin’ on the Ritz’: Civic Players bring ‘Young Frankenstein’ to life – Yahoo

    Civic Players Deliver a Hilarious and Unforgettable Performance of ‘Young Frankenstein

    ‘Wheel of Fortune’: Amputee Wins $60,000 After Breaking Incredible ‘Curse’ – Hastings Tribune

    Wheel of Fortune’ Amputee Breaks Incredible ‘Curse’ to Win $60,000!

    North Star Sports & Entertainment Network: Coming soon – KTTC News

    North Star Sports & Entertainment Network: Coming soon – KTTC News

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Mirrors in space and underwater curtains: can technology buy us enough time to save the Arctic ice caps? – The Guardian

    Can Technology Like Space Mirrors and Underwater Curtains Buy Us Time to Save the Arctic Ice Caps?

    Naples restaurant owner prepares for hurricane season with new flood technology – Fox4Now.com

    Naples restaurant owner prepares for hurricane season with new flood technology – Fox4Now.com

    Emerging Memory and Storage Technology Market Analysis Report 2025-2034 | AI and HPC Boom Fuels Surging Demand for Fast, Low-Power Memory Devices – Yahoo Finance

    How AI and HPC Are Driving Explosive Growth in Fast, Low-Power Memory Technologies Through 2034

    Ostin Technology (OST): Volatility’s Warning or Contrarian Opportunity? – AInvest

    Ostin Technology (OST): Navigating Market Volatility – Red Flag or Hidden Opportunity?

    St. Francis Medical Center brings advanced robotic surgery technology to Northeast Louisiana – KNOE

    St. Francis Medical Center brings advanced robotic surgery technology to Northeast Louisiana – KNOE

    Wayve Expands Engineering Leadership to Power Next-Gen Autonomous Driving Technology – Silicon Canals

    Wayve Boosts Engineering Leadership to Accelerate Next-Gen Autonomous Driving Innovation

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Susquehanna Raises Penn Entertainment Inc. (PENN) Price Target. – Yahoo Finance

    Susquehanna Raises Price Target for Penn Entertainment Inc. (PENN)

    George Lopez is coming to Spokane – KXLY.com

    George Lopez is coming to Spokane – KXLY.com

    Netflix unveils Dallas immersive venue for fans of hit shows like ‘Squid Game,’ ‘Stranger Things’ – Houston Chronicle

    Step Inside Netflix’s New Dallas Immersive Experience Featuring Hits Like ‘Squid Game’ and ‘Stranger Things

    ‘Puttin’ on the Ritz’: Civic Players bring ‘Young Frankenstein’ to life – Yahoo

    Civic Players Deliver a Hilarious and Unforgettable Performance of ‘Young Frankenstein

    ‘Wheel of Fortune’: Amputee Wins $60,000 After Breaking Incredible ‘Curse’ – Hastings Tribune

    Wheel of Fortune’ Amputee Breaks Incredible ‘Curse’ to Win $60,000!

    North Star Sports & Entertainment Network: Coming soon – KTTC News

    North Star Sports & Entertainment Network: Coming soon – KTTC News

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Mirrors in space and underwater curtains: can technology buy us enough time to save the Arctic ice caps? – The Guardian

    Can Technology Like Space Mirrors and Underwater Curtains Buy Us Time to Save the Arctic Ice Caps?

    Naples restaurant owner prepares for hurricane season with new flood technology – Fox4Now.com

    Naples restaurant owner prepares for hurricane season with new flood technology – Fox4Now.com

    Emerging Memory and Storage Technology Market Analysis Report 2025-2034 | AI and HPC Boom Fuels Surging Demand for Fast, Low-Power Memory Devices – Yahoo Finance

    How AI and HPC Are Driving Explosive Growth in Fast, Low-Power Memory Technologies Through 2034

    Ostin Technology (OST): Volatility’s Warning or Contrarian Opportunity? – AInvest

    Ostin Technology (OST): Navigating Market Volatility – Red Flag or Hidden Opportunity?

    St. Francis Medical Center brings advanced robotic surgery technology to Northeast Louisiana – KNOE

    St. Francis Medical Center brings advanced robotic surgery technology to Northeast Louisiana – KNOE

    Wayve Expands Engineering Leadership to Power Next-Gen Autonomous Driving Technology – Silicon Canals

    Wayve Boosts Engineering Leadership to Accelerate Next-Gen Autonomous Driving Innovation

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Protein may hold key to preventing a tick-borne disease

September 29, 2023
in Science
Protein may hold key to preventing a tick-borne disease
Share on FacebookShare on Twitter

Protein may hold key to preventing a tick-borne disease

Ticks used in research are shown in the lab of Jason Park, an assistant research professor in WSU’s College of Veterinary Medicine. Credit: College of Veterinary Medicine/Ted S. Warren

A study led by researchers at Washington State University has pinpointed a protein that appears to play a pivotal role in how a harmful bacteria that causes the disease anaplasmosis establishes itself in ticks before being transmitted to unwitting human hosts.

Examining the zoonotic tick-borne agent Anaplasma phagocytophilum, researchers identified a protein secreted by the bacteria that is essential for its survival and spread in tick cells. The findings, which were published in the journal mBio, hold the promise of a deeper understanding of how these bacteria persist and spread within ticks, potentially opening avenues for strategies to prevent the transmission of other tick-borne diseases to humans and other animals.

“If we can unravel the mechanisms at play here, we might be able to block this protein and stop ticks from spreading the bacteria to people—we could break that whole transmission cycle,” said Jason Park, the study’s corresponding author and an assistant research professor in WSU’s College of Veterinary Medicine.

Ticks pose a significant and growing threat to humans and livestock in the United States and elsewhere. Prior research into these bacteria has predominantly concentrated on mammalian hosts while limited attention has been given to understanding how the pathogen thrives and propagates within ticks.

Anaplasma phagocytophilum is the causative agent of anaplasmosis, a disease transmitted to humans through tick bites, primarily from the black-legged tick and western black-legged tick. While treatable with antibiotics, the disease can induce symptoms such as fever, headache, chills, muscle aches and sometimes, severe illness.

During the past two decades, anaplasmosis cases have been on the rise in the U.S., increasing from 348 in 2000 to 5,655 in 2019, according to the Centers for Disease Control and Prevention. Park suspects many cases go unreported.

“It has just continued to become more common,” he said. “It’s kind of under-diagnosed and under-recognized, and it’s an increasing threat.”

Ticks contract the bacteria when feeding off an infected animal. Inside a tick, the goal for the bacteria is to get past the digestive tract and infect the salivary glands, where it will accumulate and await transmission into the next mammal the tick feeds on, perpetuating the cycle.

The researchers observed that the bacteria employ a specific secreted protein, AteA, to inject and reprogram host cells in ticks. Secreted bacterial effector proteins are able to target and manipulate host pathways to benefit the pathogen. In the case of AteA, it is essential for the bacteria’s survival in ticks by interacting with cortical actin, the structural scaffolding of the host cell.

“We’re still in the process of characterizing exactly what the protein is doing, but our research has already shown it to be the first secreted protein specifically important for ticks,” Park said.

Once the bacteria reach a mammal host, the protein no longer seems to play a role, suggesting AteA is specifically adapted for tick interactions. The researchers anticipate there are proteins in addition to AteA that contribute to the bacteria’s survival in ticks.

Park is now exploring how the bacteria regulates expression of proteins such as AteA during both mammalian and tick infections and how they distinguish between their two hosts.

“How does the bacteria know it is in the tick versus a mammal?” Park said. “The bacteria can sense that, so there’s some genetic switch.”

“Instead of trying to treat a person after they’re infected with Anaplasma phagocytophilum,” he said, “we can make it so the ticks can’t spread the bacteria.”

More information:
Jason M. Park et al, An Anaplasma phagocytophilum T4SS effector, AteA, is essential for tick infection, mBio (2023). DOI: 10.1128/mbio.01711-23

Journal information:
mBio

Citation:
Protein may hold key to preventing a tick-borne disease (2023, September 29)
retrieved 29 September 2023
from https://phys.org/news/2023-09-protein-key-tick-borne-disease.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Phys.org – https://phys.org/news/2023-09-protein-key-tick-borne-disease.html

Tags: preventingproteinscience
Previous Post

Climate model provides data-driven answer to major goal of climate research

Next Post

Politicians failing to grasp ‘scientific reality’ of climate: expert

Mirrors in space and underwater curtains: can technology buy us enough time to save the Arctic ice caps? – The Guardian

Can Technology Like Space Mirrors and Underwater Curtains Buy Us Time to Save the Arctic Ice Caps?

June 29, 2025
Guirassy latest candidate for Milan attack with 70m price tag – Yahoo Sports

Guirassy Emerges as Milan’s Top Striker Target with €70 Million Price Tag

June 29, 2025
‘Half the tree of life’: ecologists’ horror as nature reserves are emptied of insects – The Guardian

Half the Tree of Life at Risk: Ecologists Warn as Insect Populations Plummet in Nature Reserves

June 29, 2025
Health, science cuts affect future jobs – The Acorn

Health, science cuts affect future jobs – The Acorn

June 29, 2025
Why Some People Have Absolutely No Sense Of Direction, According To Science – YourTango

Why Do Some People Struggle with Direction? The Surprising Science of Getting Lost

June 29, 2025
Cardiologist shares how stress and modern lifestyle are raising heart risks in 30s and 40s: ‘Don’t wait for chest pain’ | Health – Hindustan Times – Hindustan Times

Cardiologist shares how stress and modern lifestyle are raising heart risks in 30s and 40s: ‘Don’t wait for chest pain’ | Health – Hindustan Times – Hindustan Times

June 29, 2025
79-year old man competing in his 16th World Police and Fire Games – WVTM

79-year old man competing in his 16th World Police and Fire Games – WVTM

June 29, 2025
The Economy Is So Off the Rails That They’re Trying to Figure Out How to Make Ads Specifically Targeted at AI Bots – Futurism

The Economy Is So Off the Rails That They’re Trying to Figure Out How to Make Ads Specifically Targeted at AI Bots – Futurism

June 29, 2025

WATCH: Health Secretary RFK Jr. Faces Intense Questioning on Vaccine Policy and Transparency in House Hearing

June 29, 2025
Jimmy Patronis hails House passage of bill benefitting military, veterans – Florida Politics

Jimmy Patronis Cheers House Approval of Landmark Bill Backing Military and Veterans

June 29, 2025

Categories

Archives

June 2025
MTWTFSS
 1
2345678
9101112131415
16171819202122
23242526272829
30 
« May    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (700)
  • Economy (723)
  • Entertainment (21,613)
  • General (15,621)
  • Health (9,762)
  • Lifestyle (728)
  • News (22,149)
  • People (724)
  • Politics (729)
  • Science (15,940)
  • Sports (21,220)
  • Technology (15,708)
  • World (703)

Recent News

Mirrors in space and underwater curtains: can technology buy us enough time to save the Arctic ice caps? – The Guardian

Can Technology Like Space Mirrors and Underwater Curtains Buy Us Time to Save the Arctic Ice Caps?

June 29, 2025
Guirassy latest candidate for Milan attack with 70m price tag – Yahoo Sports

Guirassy Emerges as Milan’s Top Striker Target with €70 Million Price Tag

June 29, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version