* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Thursday, August 28, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    ‘SNL’ Parts Ways With Emil Wakim Amid Rumored Season 51 Cast Shakeup – yahoo.com

    SNL Shakes Up Season 51 Cast with Emil Wakim’s Surprising Exit

    Do you have a favorable or an unfavorable opinion of Taylor Swift? – YouGov

    Do You Love Taylor Swift or Not? Share Your Thoughts!

    Upload Season 4 Review – yahoo.com

    Upload Season 4 Review: A Thrilling New Chapter Unveiled

    ‘The Roses’ review: Olivia Colman, Benedict Cumberbatch sparkle in dark comedy – Yakima Herald-Republic

    The Roses’ Review: Olivia Colman and Benedict Cumberbatch Shine in Dark Comedy Delight

    ‘When Calls the Heart’ Fans All Want the Same Thing After Seeing the Show’s Latest Update – yahoo.com

    When Calls the Heart’ Fans Rally Together in Excitement Over Exciting New Update!

    Quotes of the Week: Peacemaker, Project Runway, Countdown and More – yahoo.com

    This Week’s Most Memorable Quotes from Peacemaker, Project Runway, Countdown, and More!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    ITSWC 2025: Thursday sessions guide – Traffic Technology Today

    Your Ultimate Guide to Thursday Sessions at ITSWC 2025

    MC Machinery Technology Summit Showcases Manufacturing Innovations – Modern Machine Shop

    MC Machinery Technology Summit Unveils Cutting-Edge Manufacturing Innovations

    US-ROK Technology Cooperation Faces Rising Tensions – The National Interest

    Rising Tensions Put US-South Korea Technology Partnership to the Test

    The Role of AI and Technology in Shaping the Future of Interactive Entertainment – Technology Org

    How AI and Technology Are Transforming the Future of Interactive Entertainment

    Ten upcoming sports stadiums where technology takes to the field – Dezeen

    10 Futuristic Sports Stadiums Revolutionizing the Game with Cutting-Edge Technology

    Figure Technology Solutions, Inc. Files Registration Statement for Proposed Initial Public Offering – Business Wire

    Figure Technology Solutions, Inc. Unveils Exciting Plans for Its Upcoming Initial Public Offering

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    ‘SNL’ Parts Ways With Emil Wakim Amid Rumored Season 51 Cast Shakeup – yahoo.com

    SNL Shakes Up Season 51 Cast with Emil Wakim’s Surprising Exit

    Do you have a favorable or an unfavorable opinion of Taylor Swift? – YouGov

    Do You Love Taylor Swift or Not? Share Your Thoughts!

    Upload Season 4 Review – yahoo.com

    Upload Season 4 Review: A Thrilling New Chapter Unveiled

    ‘The Roses’ review: Olivia Colman, Benedict Cumberbatch sparkle in dark comedy – Yakima Herald-Republic

    The Roses’ Review: Olivia Colman and Benedict Cumberbatch Shine in Dark Comedy Delight

    ‘When Calls the Heart’ Fans All Want the Same Thing After Seeing the Show’s Latest Update – yahoo.com

    When Calls the Heart’ Fans Rally Together in Excitement Over Exciting New Update!

    Quotes of the Week: Peacemaker, Project Runway, Countdown and More – yahoo.com

    This Week’s Most Memorable Quotes from Peacemaker, Project Runway, Countdown, and More!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    ITSWC 2025: Thursday sessions guide – Traffic Technology Today

    Your Ultimate Guide to Thursday Sessions at ITSWC 2025

    MC Machinery Technology Summit Showcases Manufacturing Innovations – Modern Machine Shop

    MC Machinery Technology Summit Unveils Cutting-Edge Manufacturing Innovations

    US-ROK Technology Cooperation Faces Rising Tensions – The National Interest

    Rising Tensions Put US-South Korea Technology Partnership to the Test

    The Role of AI and Technology in Shaping the Future of Interactive Entertainment – Technology Org

    How AI and Technology Are Transforming the Future of Interactive Entertainment

    Ten upcoming sports stadiums where technology takes to the field – Dezeen

    10 Futuristic Sports Stadiums Revolutionizing the Game with Cutting-Edge Technology

    Figure Technology Solutions, Inc. Files Registration Statement for Proposed Initial Public Offering – Business Wire

    Figure Technology Solutions, Inc. Unveils Exciting Plans for Its Upcoming Initial Public Offering

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Unlocking the Secret of Aging: Scientists Uncover Surprising Role of Long Genes

March 25, 2024
in Science
Unlocking the Secret of Aging: Scientists Uncover Surprising Role of Long Genes
Share on FacebookShare on Twitter

DNA Functions Concept

New research has identified the length of genes as a central factor in the aging process, with long genes playing a significant role in both the acceleration and deceleration of aging. This insight shifts the focus from specific aging genes to the broader impact of gene length, offering new avenues for understanding and potentially addressing age-related changes and diseases.

What causes our body to age? Four complementary studies, including one from Northwestern Medicine, have come to the same conclusion: long genes.

In a new paper, the scientists write about their findings and how they advance existing knowledge about aging.

“Long genes that become less active with age may be the central cause of aging in our bodies,” said co-corresponding author Thomas Stoeger, assistant professor of medicine in pulmonary and critical care at Northwestern University Feinberg School of Medicine and a member of the Potocsnak Longevity Institute. “Our finding advances the field by identifying a single phenomenon that connects most existing knowledge about aging and makes this underlying phenomenon measurable.”

Gene Length and Biological Aging

The paper, which highlighted the shared findings of four international research groups, was published in Trends in Genetics on March 21. The groups are the first to arrive at the conclusion that most aspects of biological aging relate to gene length.

Conditions known to accelerate aging decrease the activity of long genes. This includes smoking, alcohol, oxidative stress, and UV-irradiation. Conditions known to slow aging increase the activity of long genes such as caloric restriction. Also, genes that are very short or very long encode for cellular processes known to change in aging such as the formation of cellular energy, protein synthesis, and transmission of neural signals.

The Link Between Long Genes and Aging

“The regulation of genes is one of the most central processes of life, and our four studies explain why the activity of long genes in particular change in aging,” Stoeger said. “In addition to aging, we show that the same finding occurs in patients with Alzheimer’s disease, an age-associated disease. Our findings help us rethink the causes of neurodegenerative diseases such as Alzheimer’s disease. Because genes with neural function are unusually long, we hypothesize that the decreased activity of long genes cells fails to produce sufficient biomaterials to properly maintain neural function.”

The trigger of aging is a physical phenomenon related to the length of the genes and not to the specific genes involved or the function of those genes, the scientists report. The original findings were based on a mixture of molecular data from humans, mice, rats, killifish, C. elegans, D. melanogaster, and experiments in mice. Previously scientific research sought to identify specific genes responsible for aging. This new view differs from prevailing biological approaches that study the effects of single genes.

DNA Damage and Aging

Long genes simply have more potential sites that could be damaged. The scientists compare it to a road trip — the longer the trip, the more likely that something will go wrong. And because the physiological roles of some cell types rely upon genes that are longer than those of other cell types, some cell types are more likely to be affected by DNA damage that accumulates as they age. During aging, genes take damage as the strands of DNA that contain the genes break. This stops cells from reading the information and activating the information contained in the gene. The longer the gene, the more likely it is that at least one DNA damage site exists and stops the gene’s activation.

Because neural cells are known to rely on particularly long genes and are slow or non-dividing, they are especially susceptible to the phenomenon. Many of the genes involved in brain loss during aging and associated with Alzheimer’s disease are exceptionally long. Pediatric cancer patients, who are cured by DNA-damaging chemotherapy, later suffer from premature aging, including neurodegeneration.

Reference: “Time is ticking faster for long genes in aging” by Sourena Soheili-Nezhad, Olga Ibáñez-Solé, Ander Izeta, Jan H.J. Hoeijmakers and Thomas Stoeger, 21 March 2024, Trends in Genetics.
DOI: 10.1016/j.tig.2024.01.009

The research from Northwestern was supported by grant R00AG068544 from the National Institute on Aging of the National Institutes of Health.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : SciTechDaily – https://scitechdaily.com/unlocking-the-secret-of-aging-scientists-uncover-surprising-role-of-long-genes/

Tags: scienceSecretUnlocking
Previous Post

Warning: Sweetened Drinks Linked to Irregular Heart Rhythms

Next Post

Unlocking TNA: Researchers Develop Artificial Building Blocks of Life

Ecological Concerns – The Portugal News

Rising Ecological Concerns Threaten Portugal’s Natural Heritage

August 28, 2025
Scientists warn ocean-based climate fixes lack rules and oversight – Mongabay

Scientists warn ocean-based climate fixes lack rules and oversight – Mongabay

August 28, 2025
Posco student volunteers take science projects abroad – The Korea Herald

Posco Student Volunteers Ignite Curiosity with Science Projects in Communities Abroad

August 28, 2025
Mediterranean diet with lifestyle changes lowers diabetes risk by 31% – News-Medical

Adopting a Mediterranean Diet and Lifestyle Cuts Diabetes Risk by 31%

August 28, 2025
ITSWC 2025: Thursday sessions guide – Traffic Technology Today

Your Ultimate Guide to Thursday Sessions at ITSWC 2025

August 28, 2025
Real Madrid Graduate School Universidad Europea and UNO Launch Dual Degree in Sports Management – University of Nebraska Omaha

Real Madrid Graduate School and UNO Launch Exciting New Dual Degree in Sports Management

August 28, 2025
Hamburg Township baton twirlers capture world championship title in Italy – WXYZ Channel 7

Hamburg Township Baton Twirlers Triumph as World Champions in Italy

August 28, 2025
Diversification helps Minnesota farm navigate ag economy slump – Brownfield Ag News

How Diversification is Powering a Minnesota Farm’s Success During Tough Agricultural Times

August 28, 2025
‘SNL’ Parts Ways With Emil Wakim Amid Rumored Season 51 Cast Shakeup – yahoo.com

SNL Shakes Up Season 51 Cast with Emil Wakim’s Surprising Exit

August 28, 2025
CDC Director Susan Monarez ousted, four other leaders quit health agency – CNBC

Top Health Officials Resign Amid Controversy as CDC Director Susan Monarez Is Ousted

August 28, 2025

Categories

Archives

August 2025
MTWTFSS
 123
45678910
11121314151617
18192021222324
25262728293031
« Jul    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (794)
  • Economy (813)
  • Entertainment (21,692)
  • General (16,717)
  • Health (9,854)
  • Lifestyle (827)
  • News (22,149)
  • People (814)
  • Politics (821)
  • Science (16,023)
  • Sports (21,312)
  • Technology (15,794)
  • World (795)

Recent News

Ecological Concerns – The Portugal News

Rising Ecological Concerns Threaten Portugal’s Natural Heritage

August 28, 2025
Scientists warn ocean-based climate fixes lack rules and oversight – Mongabay

Scientists warn ocean-based climate fixes lack rules and oversight – Mongabay

August 28, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version