* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Friday, June 6, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    9 things to do this weekend in Lake County plus a look ahead – Leesburg Daily Commercial

    Discover 9 Exciting Weekend Adventures in Lake County and What’s Coming Up!

    Shows to Watch – The Advocate

    Must-See Shows You Can’t Miss!

    Fox News Entertainment Newsletter: Celebrities mentioned during Diddy’s high-profile sex trafficking trial – Fox News

    Fox News Entertainment Newsletter: Celebrities mentioned during Diddy’s high-profile sex trafficking trial – Fox News

    ‘Sinners,’ starring Michael B. Jordan, is now streaming on Prime Video – About Amazon

    Experience the Thrills of ‘Sinners’ Starring Michael B. Jordan – Now Streaming on Prime Video!

    California Mid-State Fair announces entertainment lineups for Frontier and Mission stages – KSBY News

    Exciting Entertainment Lineup Unveiled for California Mid-State Fair’s Frontier and Mission Stages!

    Spotify & OpenAI: Will Gen AI ‘Hollow Out’ Entertainment? – Technology Magazine

    Will Generative AI Transform the Future of Entertainment

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Property Technology Magazine Unveils “PropTech Top 50 Index” and the “2025 PropTech Trends Report – The Great Rebuild.” – Business Wire

    Property Technology Magazine Unveils “PropTech Top 50 Index” and the “2025 PropTech Trends Report – The Great Rebuild.” – Business Wire

    Micron Technology (NASDAQ:MU) Stock Price Expected to Rise, UBS Group Analyst Says – MarketBeat

    UBS Analyst Predicts Surge in Micron Technology Stock Price!

    Domo to Participate in the D.A. Davidson Technology Summit – Business Wire

    Domo Set to Shine at the D.A. Davidson Technology Summit!

    When fiction becomes fact: 3 pieces of modern technology inspired by Star Trek – Redshirts Always Die

    From Screen to Reality: 3 Modern Technologies Inspired by Star Trek

    The Isfahan Center for Nuclear Technology – UCF, ZPP, and IRR10 – Alma Research and Education Center

    Exploring the Isfahan Center for Nuclear Technology: Innovations and Insights from UCF, ZPP, and IRR10

    Inside the tedious effort to tally AI’s energy appetite – MIT Technology Review

    Inside the tedious effort to tally AI’s energy appetite – MIT Technology Review

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    9 things to do this weekend in Lake County plus a look ahead – Leesburg Daily Commercial

    Discover 9 Exciting Weekend Adventures in Lake County and What’s Coming Up!

    Shows to Watch – The Advocate

    Must-See Shows You Can’t Miss!

    Fox News Entertainment Newsletter: Celebrities mentioned during Diddy’s high-profile sex trafficking trial – Fox News

    Fox News Entertainment Newsletter: Celebrities mentioned during Diddy’s high-profile sex trafficking trial – Fox News

    ‘Sinners,’ starring Michael B. Jordan, is now streaming on Prime Video – About Amazon

    Experience the Thrills of ‘Sinners’ Starring Michael B. Jordan – Now Streaming on Prime Video!

    California Mid-State Fair announces entertainment lineups for Frontier and Mission stages – KSBY News

    Exciting Entertainment Lineup Unveiled for California Mid-State Fair’s Frontier and Mission Stages!

    Spotify & OpenAI: Will Gen AI ‘Hollow Out’ Entertainment? – Technology Magazine

    Will Generative AI Transform the Future of Entertainment

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Property Technology Magazine Unveils “PropTech Top 50 Index” and the “2025 PropTech Trends Report – The Great Rebuild.” – Business Wire

    Property Technology Magazine Unveils “PropTech Top 50 Index” and the “2025 PropTech Trends Report – The Great Rebuild.” – Business Wire

    Micron Technology (NASDAQ:MU) Stock Price Expected to Rise, UBS Group Analyst Says – MarketBeat

    UBS Analyst Predicts Surge in Micron Technology Stock Price!

    Domo to Participate in the D.A. Davidson Technology Summit – Business Wire

    Domo Set to Shine at the D.A. Davidson Technology Summit!

    When fiction becomes fact: 3 pieces of modern technology inspired by Star Trek – Redshirts Always Die

    From Screen to Reality: 3 Modern Technologies Inspired by Star Trek

    The Isfahan Center for Nuclear Technology – UCF, ZPP, and IRR10 – Alma Research and Education Center

    Exploring the Isfahan Center for Nuclear Technology: Innovations and Insights from UCF, ZPP, and IRR10

    Inside the tedious effort to tally AI’s energy appetite – MIT Technology Review

    Inside the tedious effort to tally AI’s energy appetite – MIT Technology Review

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Unveiling the Molecular Conspiracy: COVID-19’s Exploitation of Fragile X

March 22, 2024
in Science
Unveiling the Molecular Conspiracy: COVID-19’s Exploitation of Fragile X
Share on FacebookShare on Twitter

Molecular SARS-CoV-2 Virus Art Concept

A new study reveals how the coronavirus SARS-CoV-2 interacts with Fragile X-related proteins, impacting its spread and suggesting increased vulnerability for individuals with Fragile X Syndrome. Credit: SciTechDaily.com

Researchers have found an unexpected connection between coronavirus and Fragile X Syndrome, which is the most common hereditary cause of intellectual disability.

How does coronavirus spread through the body? A new study can help us answer that question. Professor Jakob Nilsson from the Novo Nordisk Foundation Center for Protein Research is one of the researchers responsible for the study.

“When a virus infects the body, it hijacks part of the body’s machinery either to produce new virus particles or to counteract the cell’s antiviral defense. What we wanted to know was which part of the machinery SARS-CoV-2 targets,” Jakob Nilsson says.

SARS-CoV-2 is the coronavirus variant that caused the COVID-19 pandemic.

“This suggests that we should perhaps be more attentive to these patients.” — Professor Jakob Nilsson

“We were extremely surprised to find that SARS-CoV-2 hijacks proteins associated with Fragile X Syndrome, which is the most common hereditary cause of intellectual disability,” Jakob Nilsson says.

To further explore the connection between coronavirus and the Fragile X-related proteins, Postdoc Dimitriya Garvanska, who did the lab work, used various cell-biological and biochemical methods to understand the process.

The team wanted to know whether hijacking the Fragile X-related proteins was vital to the virus’ ability to spread through the body. Together with a group of researchers from the University of Texas Medical Branch, they therefore produced a ‘mutant virus’.

Fragile X Syndrome

The syndrome, which is caused by a defect in the so-called FMR1 gene, is the most common cause of hereditary intellectual disability.It is characterised by intellectual disability – often moderate to severe in boys/men and mild in girls/women.Around 1 in 4,000 baby boys and 1 in 10,000 baby girls are born with Fragile X Syndrome.

“We mutated a small part of the virus protein, NSP3, that binds to the Fragile X-related proteins, and the cell culture test showed that this reduces the virus’ ability to spread. Moreover, tests on hamsters showed that infection with the mutated virus had a less severe impact on the lungs in the early stages of infection,” Dimitriya Garvanska explains and adds:

“That is, binding to Fragile X-related proteins is vital to the virus’ ability to spread. Subsequent tests showed that these proteins are part of the cell’s antiviral defense, and that SARS-CoV-2 seeks to counteract this defense system by hijacking the proteins.”

The results of the study may indicate that persons with Fragile X Syndrome are more susceptible to infection with SARS-CoV-2 and other viruses.

“This suggests that we should perhaps be more attentive to these patients,” Jakob Nilsson says.

The study provides insight into the possible cause of Fragile X Syndrome

Aside from identifying the connection between coronavirus and Fragile X Syndrome, Jakob Nilsson, Dimitriya Garvanska and their colleagues also gained a deeper understanding of Fragile X Syndrome.

“We know that Fragile X-related proteins are key to brain development. Because when we do not have enough of them, we run into problems. But we do not know why they are so important. In this study, we have learned that they bind to another protein, UBAP2L, which helps determine which proteins the cell produces,” Jakob Nilsson says.

The researchers also found that mutations in the Fragile X-related proteins prevent them from binding to UBAP2L.

“This suggests that to understand Fragile X Syndrome we need to understand how this affects the production of proteins in the cell,” Jakob Nilsson explains.

While the new study can be described as fundamental research, the results may nevertheless prove useful in future treatment.

“So far, this is speculation. But basically, the more insight we gain into these mechanisms, the better are our chances of impacting them in the future,” Jakob Nilsson concludes.

You can read the study “SARS-CoV-2 hijacks fragile X mental retardation proteins for efficient infection” in EMBO Reports.

Reference: “The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions” by Dimitriya H Garvanska, R Elias Alvarado, Filip Oskar Mundt, Richard Lindqvist, Josephine Kerzel Duel, Fabian Coscia, Emma Nilsson, Kumari Lokugamage, Bryan A Johnson, Jessica A Plante, Dorothea R Morris, Michelle N Vu, Leah K Estes, Alyssa M Mc Leland, Jordyn Walker, Patricia A Crocquet-Valdes, Blanca Lopez Mendez, Kenneth S Plante, David H Walker, Melanie Bianca Weisser, Anna K Överby, Matthias Mann, Vineet D Menachery and Jakob Nilsson, 2 January 2024, EMBO Reports.
DOI: 10.1038/s44319-023-00043-z

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : SciTechDaily – https://scitechdaily.com/unveiling-the-molecular-conspiracy-covid-19s-exploitation-of-fragile-x/

Tags: molecularscienceUnveiling
Previous Post

Webb’s “Astonishing Discovery” of Huge Black Holes in Early Universe – “Thought To Be Impossible”

Next Post

Zero Emissions of Carbon Dioxide! New Method Produces Ammonia-Based Clean Hydrogen

Hollywood legend Tom Cruise becomes record holder for his fiery Mission Impossible stunt – Guinness World Records

Tom Cruise Sets the Bar High with Record-Breaking Fiery Stunt in Mission Impossible!

June 6, 2025
India could become third largest economy in the world this year: Borge Brende – MSN

India Poised to Become the World’s Third Largest Economy This Year!

June 6, 2025
9 things to do this weekend in Lake County plus a look ahead – Leesburg Daily Commercial

Discover 9 Exciting Weekend Adventures in Lake County and What’s Coming Up!

June 6, 2025
Property Technology Magazine Unveils “PropTech Top 50 Index” and the “2025 PropTech Trends Report – The Great Rebuild.” – Business Wire

Property Technology Magazine Unveils “PropTech Top 50 Index” and the “2025 PropTech Trends Report – The Great Rebuild.” – Business Wire

June 6, 2025
Graphics: China’s ecological, environmental quality keeps improving steadily – news.cgtn.com

Graphics: China’s ecological, environmental quality keeps improving steadily – news.cgtn.com

June 5, 2025
The Forgotten History (and Slippery Science) of Canola Oil – Eater

The Forgotten History (and Slippery Science) of Canola Oil – Eater

June 5, 2025

The White House Gutted Science Funding. Now It Wants to ‘Correct’ Research. – The New York Times

June 5, 2025
Celsius targets active lifestyles in brand’s largest campaign to date – Marketing Dive

Celsius Unleashes Its Boldest Campaign Yet to Energize Active Lifestyles!

June 5, 2025
Here Are The WFDF World Under-24 Ultimate Championships Pools – Ultiworld

Exciting Matchups Ahead: Discover the Pools for the WFDF World Under-24 Ultimate Championships!

June 5, 2025
Iowa GOP Chair responds to report ranking Iowa as state with worst economy – KCRG

Iowa GOP Chair responds to report ranking Iowa as state with worst economy – KCRG

June 5, 2025

Categories

Archives

June 2025
MTWTFSS
 1
2345678
9101112131415
16171819202122
23242526272829
30 
« May    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (669)
  • Economy (684)
  • Entertainment (21,590)
  • General (15,267)
  • Health (9,725)
  • Lifestyle (686)
  • News (22,149)
  • People (684)
  • Politics (691)
  • Science (15,901)
  • Sports (21,187)
  • Technology (15,669)
  • World (669)

Recent News

Hollywood legend Tom Cruise becomes record holder for his fiery Mission Impossible stunt – Guinness World Records

Tom Cruise Sets the Bar High with Record-Breaking Fiery Stunt in Mission Impossible!

June 6, 2025
India could become third largest economy in the world this year: Borge Brende – MSN

India Poised to Become the World’s Third Largest Economy This Year!

June 6, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version