* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Sunday, June 8, 2025
Earth-News
  • Home
  • Business
  • Entertainment
  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Reeves to Announce £86 Billion for Science and Technology in Spending Review – Bloomberg

    Reeves Set to Unveil Groundbreaking £86 Billion Investment in Science and Technology!

    Innovation at Scale: How P&G Transforms Business Through Technology – Procter & Gamble

    Revolutionizing Business: P&G’s Bold Journey into Technological Innovation

    Drag racer survives frightening airborne crash at World Wide Technology Raceway – FOX 2

    Drag racer survives frightening airborne crash at World Wide Technology Raceway – FOX 2

    Apple Watch and the future of wearable technology in healthcare – MSN

    Revolutionizing Healthcare: The Future of Wearable Technology with Apple Watch

    ECS Professor Pankaj K. Jha Receives NSF Grant to Develop Quantum Technology – Syracuse University News

    Unlocking the Future: ECS Professor Pankaj K. Jha Secures NSF Grant for Groundbreaking Quantum Technology Development

    Fire Tech Brief: 5 Fire Apparatus Technology Upgrades – firehouse.com

    Revving Up Safety: 5 Innovative Upgrades for Fire Apparatus Technology

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Reeves to Announce £86 Billion for Science and Technology in Spending Review – Bloomberg

    Reeves Set to Unveil Groundbreaking £86 Billion Investment in Science and Technology!

    Innovation at Scale: How P&G Transforms Business Through Technology – Procter & Gamble

    Revolutionizing Business: P&G’s Bold Journey into Technological Innovation

    Drag racer survives frightening airborne crash at World Wide Technology Raceway – FOX 2

    Drag racer survives frightening airborne crash at World Wide Technology Raceway – FOX 2

    Apple Watch and the future of wearable technology in healthcare – MSN

    Revolutionizing Healthcare: The Future of Wearable Technology with Apple Watch

    ECS Professor Pankaj K. Jha Receives NSF Grant to Develop Quantum Technology – Syracuse University News

    Unlocking the Future: ECS Professor Pankaj K. Jha Secures NSF Grant for Groundbreaking Quantum Technology Development

    Fire Tech Brief: 5 Fire Apparatus Technology Upgrades – firehouse.com

    Revving Up Safety: 5 Innovative Upgrades for Fire Apparatus Technology

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Science

Weight Loss’ Secret Weapon: GDF15 Powers Calorie Burn During Dieting

July 2, 2023
in Science
Weight Loss’ Secret Weapon: GDF15 Powers Calorie Burn During Dieting
Share on FacebookShare on Twitter

Obesity Weight Loss

Researchers at McMaster University have found that the hormone GDF15, previously linked to reduced appetite due to metformin, could also help with weight loss by maintaining metabolism during dieting. This could lead to improved weight loss therapies and offer insights into individual variations in dieting success.

Research opens new possibilities to help people maintain weight loss after dieting.

Researchers led by McMaster University professor Gregory Steinberg and postdoctoral research fellow Dongdong Wang have uncovered a key mechanism for promoting weight loss and maintaining the burning of calories during dieting.

The research team studied a hormone called GDF15 that they had previously shown to reduce appetite in response to the type 2 diabetes drug metformin. Their latest findings, published in Nature on June 28, showed that GDF15 also has the potential to help with weight loss.

The research opens new possibilities to help people maintain weight loss after dieting, as well as the potential to develop combination therapies with GDF15 and currently available drugs that suppress appetite to promote further weight loss. Obesity, a global concern affecting one billion people, is linked to many metabolic disorders including type 2 diabetes. It has long been a target of research on effective weight loss methods.

Dongdong Wang and Gregory Steinberg

Dongdong Wang, first author and postdoctoral research fellow and Gregory Steinberg, professor of Medicine at McMaster University and co-director of the Centre for Metabolism, Obesity, and Diabetes Research at McMaster University. Credit: McMaster University

“We have discovered that in mice, GDF15 blocks the slowing of metabolism that occurs during dieting by ramping up calcium futile cycling in muscle,” said Steinberg, a professor of the Department of Medicine at McMaster University and co-director of the Centre for Metabolism, Obesity, and Diabetes Research.

“Our study highlights the potential of the hormone GDF15 to not only reduce the desire to eat fatty foods but also simultaneously boost energy burning in muscle.”

While calorie restriction initially leads to weight loss, the body’s metabolism eventually slows this process down, reducing its effectiveness. The research showed, however, that mice treated with GDF15 continued losing weight while consuming the same number of calories as the control group. This increase in energy burn occurred in their muscles but not fat tissue.

More research is needed to confirm these findings in humans, said Steinberg. He said that understanding how GDF15 levels impact muscle energy burning in humans could help explain why people have diverse levels of success in losing weight with dieting.

Further research on GDF15 might also provide new ways to help individuals who struggle to lose weight through traditional diets and may extend the benefits of recently approved appetite-suppressing drugs that target the GLP1 receptor.

Reference: “GDF15 promotes weight loss by enhancing energy expenditure in muscle” by Dongdong Wang, Logan K. Townsend, Geneviève J. DesOrmeaux, Sara M. Frangos, Battsetseg Batchuluun, Lauralyne Dumont, Rune Ehrenreich Kuhre, Elham Ahmadi, Sumei Hu, Irena A. Rebalka, Jaya Gautam, Maria Joy Therese Jabile, Chantal A. Pileggi, Sonia Rehal, Eric M. Desjardins, Evangelia E. Tsakiridis, James S. V. Lally, Emma Sara Juracic, A. Russell Tupling, Hertzel C. Gerstein, Guillaume Paré, Theodoros Tsakiridis, Mary-Ellen Harper, Thomas J. Hawke, John R. Speakman, Denis P. Blondin, Graham P. Holloway, Sebastian Beck Jørgensen and Gregory R. Steinberg, 28 June 2023, Nature.
DOI: 10.1038/s41586-023-06249-4

This analysis of the impact of GDF15 on weight loss is the result of a collaboration with Novo Nordisk and researchers from Ottawa, Waterloo, Sherbrooke, Beijing, and Guelph.

This work was funded in part by Diabetes Canada, the Canadian Institutes of Health Research, and Novo Nordisk.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : SciTechDaily – https://scitechdaily.com/weight-loss-secret-weapon-gdf15-powers-calorie-burn-during-dieting/

Tags: Loss’scienceWeight
Previous Post

Cross River govt will adopt ‘monkey work, monkey chop’ in giving appointments: APC

Next Post

Preparing for Asteroid Bennu: NASA’s OSIRIS-REx Astromaterials Lab Opens Doors to Media

Reeves to Announce £86 Billion for Science and Technology in Spending Review – Bloomberg

Reeves Set to Unveil Groundbreaking £86 Billion Investment in Science and Technology!

June 8, 2025
Shotgun sequencing of airborne eDNA achieves rapid assessment of whole biomes, population genetics and genomic variation – Nature

Revolutionizing Biodiversity: Rapid Insights into Ecosystems and Genetic Diversity Through Shotgun Sequencing of Airborne eDNA

June 8, 2025
Earth’s energy balance is rising much faster than scientists predicted, and we have no idea why – Live Science

Unraveling the Mystery: Earth’s Energy Balance is Surging Faster Than Expected!

June 8, 2025
The Undermining of Science — and Society — Continues – UExpress

How the Erosion of Science is Impacting Our Society

June 8, 2025
10 habits that secretly ‘kill’ your happy hormones – Times of India

10 Surprising Habits That Sabotage Your Happy Hormones

June 8, 2025
A GPS Blackout Would Shut Down the World – WIRED

How a GPS Blackout Could Bring the World to a Standstill

June 8, 2025
Six Steps To Ruin a Country’s Image, Economy, and Global Standing | Opinion – Newsweek

Six Surefire Ways to Dismantle a Nation’s Reputation and Prosperity

June 8, 2025
Middle Eastern Entertainment Headlines at 5:49 a.m. GMT – Yahoo

Exciting Updates from the Middle Eastern Entertainment Scene!

June 8, 2025
Omada shares rise 21% in Nasdaq debut after health tech company’s IPO – CNBC

Omada Soars 21% in Thrilling Nasdaq Debut Following Successful IPO!

June 8, 2025
Politics-Based Investing Sounds Smart. But These Strategies Work Better. – Barron’s

Politics-Based Investing Sounds Smart. But These Strategies Work Better. – Barron’s

June 8, 2025

Categories

Archives

June 2025
MTWTFSS
 1
2345678
9101112131415
16171819202122
23242526272829
30 
« May    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (677)
  • Economy (690)
  • Entertainment (21,596)
  • General (15,271)
  • Health (9,732)
  • Lifestyle (694)
  • News (22,149)
  • People (691)
  • Politics (698)
  • Science (15,909)
  • Sports (21,193)
  • Technology (15,677)
  • World (675)

Recent News

Reeves to Announce £86 Billion for Science and Technology in Spending Review – Bloomberg

Reeves Set to Unveil Groundbreaking £86 Billion Investment in Science and Technology!

June 8, 2025
Shotgun sequencing of airborne eDNA achieves rapid assessment of whole biomes, population genetics and genomic variation – Nature

Revolutionizing Biodiversity: Rapid Insights into Ecosystems and Genetic Diversity Through Shotgun Sequencing of Airborne eDNA

June 8, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version