Wireless microelectronic fibers to discover gut and brain pathways

We created miniature and flexible polymer fibers equipped with optoelectronic microdevices, microfluidics and electrodes that can be implanted in anatomically disparate organs such as the brain and the intestine. The microelectronic fibers can be operated wirelessly to sense and manipulate brain and gut neural circuits in untethered, behaving mice.

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Fig. 1: Multifunctional microelectronic fibers enable wireless gut–brain neuromodulation.

References

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This is a summary of: Sahasrabudhe, A. et al. Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-01833-5 (2023).