NFL Week 6 Odds: Best Picks to Bet on Sunday’s Schedule

NFL Week 6 Odds: Best Picks to Bet on Sunday’s Schedule

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The 49ers are looking to remain unbeaten this weekend in a matchup against the Browns, and there’s little doubt they’ll accomplish the feat.

However, San Francisco’s odds to win the matchup are -500, so the best bet to take here would be the Niners to cover the spread at -9.5.

Cleveland boasts a strong defense headed by Myles Garrett, but the Browns have yet to face an elite offense this season, facing the likes of the Pittsburgh Steelers, Cincinnati Bengals, Tennessee Titans and Baltimore Ravens to begin the year.

The 49ers represent the Browns’ toughest challenge yet, and there’s little doubt San Francisco’s explosive offense is going to put points on the board.

San Francisco is averaging the second-most points per game in the NFL this season (33.4 PPG) behind the Miami Dolphins. Additionally, star running back Christian McCaffrey leads the league with 510 yards and seven touchdowns on the ground.

The Browns, meanwhile, could have some trouble putting points on the board on Sunday.

Quarterback Deshaun Watson was ruled out with a shoulder injury, meaning rookie signal-caller Dorian Thompson-Robinson will get his second start of the season.

Thompson-Robinson started last weekend’s loss to the Ravens, and the Browns offense failed to score a touchdown as they fell 28-3. He completed 19 of 36 passes for 121 yards and three interceptions in the loss.

The rookie now goes up against a tough San Francisco defense headlined by Nick Bosa. The 49ers are allowing just 202.6 passing yards per game, 64.2 rushing yards per game and 13.6 points per game.

This all doesn’t bode well for the Browns, so expect the 49ers to keep rolling this weekend.

It’s also important to note San Francisco is 4-0-1 against the spread this season with three straight covers.

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