* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Saturday, August 2, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Sens. Blackburn, Warnock introduce CREATE Act to provide tax relief to music creators – Yahoo Home

    Sens. Blackburn and Warnock Launch CREATE Act to Deliver Tax Relief for Music Creators

    That’s (Political) Entertainment: When Theatre Meets Politics

    Future Script: How Generative AI Is Changing Collective Bargaining in the Entertainment Industry – Jackson Lewis

    Future Script: How Generative AI Is Transforming Collective Bargaining in Entertainment

    The SBA’s live-entertainment bailout was supposed to end two years ago. We still don’t know how $1.5 billion was spent. – Yahoo Home

    $1.5 Billion Live-Entertainment Bailout: Two Years Later, Where Did the Money Go?

    Wall Street Bets: Caesars, Golden Entertainment, Churchill Downs, GLPI, Boyd – CDC Gaming

    Top Wall Street Bets: Caesars, Golden Entertainment, Churchill Downs, GLPI, and Boyd Take Center Stage

    Micro wrestling coming to NE Ohio – Cleveland.com

    Get Ready, NE Ohio: Micro Wrestling Is Making Its Exciting Debut!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Emory orthopaedic surgeons use robotic technology to transform knee replacement surgery – Emory News Center

    How Robotic Technology is Revolutionizing Knee Replacement Surgery

    Cognizant Technology Solutions Corp (CTSH) Q2 2025 Earnings Call Highlights: Strong Revenue … – Yahoo.co

    Cognizant Q2 2025 Earnings: Impressive Revenue Growth and Key Takeaways

    Revving Up The U.S. Technology Engine – Forbes

    Revving Up The U.S. Technology Engine – Forbes

    More than just a hockey player – Rochester Institute of Technology Athletics

    Beyond the Ice: The Inspiring Journey of a Remarkable Athlete from Rochester Institute of Technology

    Smart Logistics in Warehousing – From Legacy Protocols to Green IoT – How Technology Is Reshaping the Sustainable Supply Chain – Logistics Viewpoints –

    Smart Logistics in Warehousing – From Legacy Protocols to Green IoT – How Technology Is Reshaping the Sustainable Supply Chain – Logistics Viewpoints –

    AI’s race in the dark with China – Axios

    The High-Stakes AI Race: Innovation and Competition in the Shadows

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Sens. Blackburn, Warnock introduce CREATE Act to provide tax relief to music creators – Yahoo Home

    Sens. Blackburn and Warnock Launch CREATE Act to Deliver Tax Relief for Music Creators

    That’s (Political) Entertainment: When Theatre Meets Politics

    Future Script: How Generative AI Is Changing Collective Bargaining in the Entertainment Industry – Jackson Lewis

    Future Script: How Generative AI Is Transforming Collective Bargaining in Entertainment

    The SBA’s live-entertainment bailout was supposed to end two years ago. We still don’t know how $1.5 billion was spent. – Yahoo Home

    $1.5 Billion Live-Entertainment Bailout: Two Years Later, Where Did the Money Go?

    Wall Street Bets: Caesars, Golden Entertainment, Churchill Downs, GLPI, Boyd – CDC Gaming

    Top Wall Street Bets: Caesars, Golden Entertainment, Churchill Downs, GLPI, and Boyd Take Center Stage

    Micro wrestling coming to NE Ohio – Cleveland.com

    Get Ready, NE Ohio: Micro Wrestling Is Making Its Exciting Debut!

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Emory orthopaedic surgeons use robotic technology to transform knee replacement surgery – Emory News Center

    How Robotic Technology is Revolutionizing Knee Replacement Surgery

    Cognizant Technology Solutions Corp (CTSH) Q2 2025 Earnings Call Highlights: Strong Revenue … – Yahoo.co

    Cognizant Q2 2025 Earnings: Impressive Revenue Growth and Key Takeaways

    Revving Up The U.S. Technology Engine – Forbes

    Revving Up The U.S. Technology Engine – Forbes

    More than just a hockey player – Rochester Institute of Technology Athletics

    Beyond the Ice: The Inspiring Journey of a Remarkable Athlete from Rochester Institute of Technology

    Smart Logistics in Warehousing – From Legacy Protocols to Green IoT – How Technology Is Reshaping the Sustainable Supply Chain – Logistics Viewpoints –

    Smart Logistics in Warehousing – From Legacy Protocols to Green IoT – How Technology Is Reshaping the Sustainable Supply Chain – Logistics Viewpoints –

    AI’s race in the dark with China – Axios

    The High-Stakes AI Race: Innovation and Competition in the Shadows

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Technology

Everything you need to know about artificial wombs

September 30, 2023
in Technology
Everything you need to know about artificial wombs
Share on FacebookShare on Twitter

“The most challenging question to answer is how much unknown is acceptable,” said An Massaro, FDA’s lead neonatologist in the Office of Pediatric Therapeutics, at the committee meeting. That’s a question regulators will have to grapple with as this research moves out of the lab and into first-in-human trials.

What is an artificial womb?

An artificial womb is an experimental medical device intended to provide a womblike environment for extremely premature infants. In most of the technologies, the infant would float in a clear “biobag,” surrounded by fluid. The idea is that preemies could spend a few weeks continuing to develop in this device after birth, so that “when they’re transitioned from the device, they’re more capable of surviving and having fewer complications with conventional treatment,” says George Mychaliska, a pediatric surgeon at the University of Michigan.

One of the main limiting factors for survival in extremely premature babies is lung development. Rather than breathing air, babies in an artificial womb would have their lungs filled with lab-made amniotic fluid, that mimics the amniotic fluid they would have hadjust like they would in utero. Neonatologists would insert tubes into blood vessels in the umbilical cord so that the infant’s blood could cycle through an artificial lung to pick up oxygen. 

The device closest to being ready to be tested in humans, called the EXTrauterine Environment for Newborn Development, or EXTEND, encases the baby in a container filled with lab-made amniotic fluid. It was invented by Alan Flake and Marcus Davey at the Children’s Hospital of Philadelphia and is being developed by Vitara Biomedical. 

Other researchers are working on artificial wombs too, though they’re a bit farther behind. Scientists in Australia and Japan are developing a system very similar to EXTEND. In Europe, the Perinatal Life Support project is working on its own technology. And in Canada, researchers have been testing their version of an artificial womb on piglets. Researchers at the University of Michigan are working on similar technology intended to be used within preemies for whom conventional therapies aren’t likely to work. Rather than floating in fluid, the infants would only have their lungs filled. It’s a system that could be used in existing ICUs with relatively few modifications, so “we believe that that has more clinical applicability,” says Mychaliska,who is leading the project.  

When will this technology be tested in humans?

The technology used in the EXTEND system has been tested on lamb fetuses, about 300 so far, with good results. The lambs can survive and develop inside the sack for three or even four weeks.

To move forward with human testing, the company needs an investigational device exemption from the FDA. At a meeting in June, Flake said Vitara might be ready to request that exemption in September or October. But at the September advisory committee meeting, when Flake was directly asked how far the technology had advanced he declined to answer. He said he could discuss timing with the advisory committee during the portion of the meeting that was closed to the public. To greenlight a trial, FDA officials need to be convinced that babies who try EXTEND are likely to benefit from the system, and that they’ll fare at least as well as babies who receive the current standard of care.

What would the first human tests look like?

The procedure requires a carefully choreographed transfer. First, the baby must be delivered via cesarean section and immediately have tubes inserted into the umbilical cord before being transferred into the fluid-filled container.

The technology would likely be used first on infants born at 22 or 23 weeks who don’t have many other options. “You don’t want to put an infant on this device who would otherwise do well with conventional therapy,” Mychaliska says. At 22 weeks gestation, babies are tiny, often weighing less than a pound. And their lungs are still developing. When researchers looked at babies born between 2013 and 2018, survival among those who were resuscitated at 22 weeks was 30%. That number rose to nearly 56% at 23 weeks. And babies born at that stage who do survive have an increased risk of neurodevelopmental problems, cerebral palsy, mobility problems, hearing impairments, and other disabilities. 

Selecting the right participants will be tricky. Some experts argue that gestational age shouldn’t be the only criteria. One complicating factor is that prognosis varies widely from center to center, and it’s improving as hospitals learn how best to treat these preemies. At the University of Iowa Stead Family Children’s Hospital, for example, survival rates are much higher than average: 64% for babies born at 22 weeks. They’ve even managed to keep a handful of infants born at 21 weeks alive. “These babies are not a hopeless case. They very much can survive. They very much can thrive if you are managing them appropriately,” says Brady Thomas, a neonatologist at Stead. “Are you really going to make that much of a bigger impact by adding in this technology, and what risks might exist to those patients as you’re starting to trial it?”

Prognosis also varies widely from baby to baby depending on a variety of factors. “The girls do better than the boys. The bigger ones do better than the smaller ones,” says Mark Mercurio, a neonatologist and pediatric bioethicist at the Yale School of Medicine. So “how bad does the prognosis with current therapy need to be to justify use of an artificial womb?” That’s a question Mercurio would like to see answered.

What are the risks?

One ever-present concern in the tiniest babies is brain bleeds. “That’s due to a number of factors—a combination of their brain immaturity, and in part associated with the treatment that we provide,” Mychaliska says. Babies in an artificial womb would need to be on a blood thinner to prevent clots from forming where the tubes enter the body. “I believe that places a premature infant at very high risk for brain bleeding,” he says.  

And it’s not just about the baby. To be eligible for EXTEND, infants must be delivered via cesarean section, which puts the pregnant person at higher risk for infection and bleeding. Delivery via a C-section can also have an impact on future pregnancies.  

So if it works, could babies be grown entirely outside the womb?

Not anytime soon. Maybe not ever. In a paper published in 2022, Flake and his colleagues called this scenario “a technically and developmentally naive, yet sensationally speculative, pipe dream.” The problem is twofold. First, fetal development is a carefully choreographed process that relies on chemical communication between the pregnant parent’s body and the fetus. Even if researchers understood all the factors that contribute to fetal development—and they don’t—there’s no guarantee they could recreate those conditions. 

The second issue is size. The artificial womb systems being developed require doctors to insert a small tube into the infant’s umbilical cord to deliver oxygenated blood. The smaller the umbilical cord, the more difficult this becomes.

What are the ethical concerns?

In the near term, there are concerns about how to ensure that researchers are obtaining proper informed consent from parents who may be desperate to save their babies. “This is an issue that comes up with lots of last-chance therapies,” says Vardit Ravitsky, a bioethicist and president of the Hastings Center, a bioethics research institute. 

If the artificial wombs work, more significant questions will come up. When these devices are used to save infants born too soon, “this is obviously potentially a wonderful technology,” Ravitsky says. But as with any technology, other uses might arise. Imagine that a woman wants to terminate a pregnancy at 21 or 22 weeks and this technology is available. How would that impact a woman’s right to choose whether to carry a pregnancy to term? “When we say that a woman has the right to terminate, do we mean the right to physically separate from the fetus? Or do we mean the right not to become a biological mother?” Ravitsky asks.

With the technology at an early stage, that situation might seem far-fetched, but it’s worth thinking about the implications now. Elizabeth Chloe Romanis, who studies health-care law and bioethics at Durham University in the UK, argued at the advisory meeting that “an entity undergoing gestation outside the body is a unique human entity,” one that might have different needs and require different protections. 

The advent of an artificial womb raises all kinds of questions, Ravitsky says: “What’s a fetus, what’s a baby, what’s a newborn, what’s birth, what’s viability?” These questions have ethical implications, but also legal ones. “If we don’t start thinking about it, now we’re going to have lots of blind spots,” she says.  

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Technology Review – https://www.technologyreview.com/2023/09/29/1080538/everything-you-need-to-know-about-artificial-wombs/

Tags: ArtificialEverythingtechnology
Previous Post

Elon Musk wants more bandwidth between people and machines. Do we need it?

Next Post

The Download: brain bandwidth, and artificial wombs

It’s time to retire the word ‘technology’ – Financial Times

Why It’s Time to Say Goodbye to the Word ‘Technology

August 2, 2025

Wrigley Field to host 2027 MLB All-Star Game – Yahoo Sports

August 2, 2025
Women’s Voices Are the Only Way Forward for Climate Change Solutions: ‘As Women, We Have to Stand Up and Back Up Women’ – Ms. Magazine

Women’s Voices Are the Only Way Forward for Climate Change Solutions: ‘As Women, We Have to Stand Up and Back Up Women’ – Ms. Magazine

August 1, 2025
“A Danger to the Entire Planet”: Amid Deadly Extreme Weather, Trump’s EPA Rejects Climate Science – Democracy Now!

“A Danger to the Entire Planet”: Amid Deadly Extreme Weather, Trump’s EPA Rejects Climate Science – Democracy Now!

August 1, 2025
Ten Lifestyle Group Announces Total Voting Rights and Share Capital Update – TipRanks

Ten Lifestyle Group Announces Total Voting Rights and Share Capital Update – TipRanks

August 1, 2025
Five different countries take gold medals on a wide-open day at the swim world championships – AP News

Five Countries Triumph in a Thrilling, Unpredictable Day at the Swim World Championships

August 1, 2025
US employers slash hiring as Trump advances a punishing trade agenda – AP News

US Employers Slash Hiring as Trump’s Aggressive Trade Policies Shake the Market

August 1, 2025
Duffer Brothers and Jerry Bruckheimer Join Program for Entertainment and Technology Summit – Variety

Duffer Brothers and Jerry Bruckheimer Join Forces for an Exciting Entertainment and Technology Summit

August 1, 2025
Alabama schools enhance mental health support as students return to the classroom – WBMA

Alabama Schools Ramp Up Mental Health Support as Students Return to Classrooms

August 1, 2025
Platts­burgh town su­per­visor eyed for Dem ticket in N.Y. Assembly special election – Spectrum News

Platts­burgh town su­per­visor eyed for Dem ticket in N.Y. Assembly special election – Spectrum News

August 1, 2025

Categories

Archives

August 2025
MTWTFSS
 123
45678910
11121314151617
18192021222324
25262728293031
« Jul    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (749)
  • Economy (774)
  • Entertainment (21,652)
  • General (16,232)
  • Health (9,811)
  • Lifestyle (782)
  • News (22,149)
  • People (775)
  • Politics (783)
  • Science (15,987)
  • Sports (21,270)
  • Technology (15,752)
  • World (757)

Recent News

It’s time to retire the word ‘technology’ – Financial Times

Why It’s Time to Say Goodbye to the Word ‘Technology

August 2, 2025

Wrigley Field to host 2027 MLB All-Star Game – Yahoo Sports

August 2, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version