Kidney transplant rejection is the main cause of graft failure, but detection of early-stage rejection is challenging. Current approaches are either invasive or can have false-positive or false-negative predictions owing to alteration of known rejection biomarkers due to diet, infections or medications unrelated to rejection. In a study published in Science, Madhavpathy and colleagues develop an implantable bioelectronic system for early detection of graft rejection before serum biomarkers can offer diagnostic value.
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Bishop, A. Implantable biosensor tracks temperature to detect early transplant rejection in rats.
Nat Biotechnol 41, 1386 (2023). https://doi.org/10.1038/s41587-023-01998-z
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Published: 12 October 2023
Issue Date: October 2023
DOI: https://doi.org/10.1038/s41587-023-01998-z
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