* . *
  • About
  • Advertise
  • Privacy & Policy
  • Contact
Thursday, October 16, 2025
Earth-News
  • Home
  • Business
  • Entertainment
    Arts/Entertainment: ‘Wait Until Dark’ brings spooky season center stage – Times Herald Online

    Wait Until Dark’ Delivers Chilling Thrills Perfect for the Spooky Season

    Bluesman James Montgomery Will Perform In Falmouth – CapeNews.net

    Blues Legend James Montgomery Ready to Ignite the Stage in Falmouth

    Mexican singer Pedro Fernández to make Ave Fénix tour stop in Stockton. Tickets, schedule – Yahoo

    Mexican Singer Pedro Fernández Brings the Ave Fénix Tour to Stockton – Don’t Miss It!

    Flutter Entertainment’s SWOT Analysis: Uncovering the Growth Potential Amid Challenges

    Dylan Efron Shares Sweet ‘DWTS’ Rehearsal Photos Featuring His Little Sister Olivia – yahoo.com

    Dylan Efron’s Heartwarming ‘DWTS’ Rehearsal Moments with Little Sister Olivia

    Diane Keaton, Oscar-Winning Star of ‘Annie Hall’ and ‘The Godfather,’ Dies at 79 – Yahoo

    Diane Keaton, Oscar-Winning Star of ‘Annie Hall’ and ‘The Godfather,’ Dies at 79 – Yahoo

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Erie Canal’s 200th anniversary: How a technological marvel for trade changed the environment forever – The Conversation

    Erie Canal’s 200th Anniversary: How a Trade Marvel Transformed the Environment Forever

    Day 5 of Gains Streak for Solidion Technology Stock with 475% Return (vs. -20% YTD) [10/14/2025] – Trefis

    Solidion Technology Stock Rockets for 5th Consecutive Day, Soaring an Astonishing 475% Year-to-Date

    Tracking DNA and RNA Together To Unlock Disease Insights – Technology Networks

    Unlocking Disease Insights by Tracking DNA and RNA Together

    The future of battery technology – Engineer Live

    Revolutionizing Energy: Exploring the Future of Battery Technology

    How Can Boosting Your Travel Experience with Less Technology Lead to a More Relaxing Vacation? All You Need to Know About This Latest Trend – Travel And Tour World

    How Can Boosting Your Travel Experience with Less Technology Lead to a More Relaxing Vacation? All You Need to Know About This Latest Trend – Travel And Tour World

    Davenport CornCon Cybersecurity Conference helps students explore technology, AI use – KWQC

    Davenport CornCon Cybersecurity Conference Ignites Student Passion for Technology and AI Innovations

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Arts/Entertainment: ‘Wait Until Dark’ brings spooky season center stage – Times Herald Online

    Wait Until Dark’ Delivers Chilling Thrills Perfect for the Spooky Season

    Bluesman James Montgomery Will Perform In Falmouth – CapeNews.net

    Blues Legend James Montgomery Ready to Ignite the Stage in Falmouth

    Mexican singer Pedro Fernández to make Ave Fénix tour stop in Stockton. Tickets, schedule – Yahoo

    Mexican Singer Pedro Fernández Brings the Ave Fénix Tour to Stockton – Don’t Miss It!

    Flutter Entertainment’s SWOT Analysis: Uncovering the Growth Potential Amid Challenges

    Dylan Efron Shares Sweet ‘DWTS’ Rehearsal Photos Featuring His Little Sister Olivia – yahoo.com

    Dylan Efron’s Heartwarming ‘DWTS’ Rehearsal Moments with Little Sister Olivia

    Diane Keaton, Oscar-Winning Star of ‘Annie Hall’ and ‘The Godfather,’ Dies at 79 – Yahoo

    Diane Keaton, Oscar-Winning Star of ‘Annie Hall’ and ‘The Godfather,’ Dies at 79 – Yahoo

  • General
  • Health
  • News

    Cracking the Code: Why China’s Economic Challenges Aren’t Shaking Markets, Unlike America’s” – Bloomberg

    Trump’s Narrow Window to Spread the Truth About Harris

    Trump’s Narrow Window to Spread the Truth About Harris

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    Israel-Gaza war live updates: Hamas leader Ismail Haniyeh assassinated in Iran, group says

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    PAP Boss to Niger Delta Youths, Stay Away from the Protest

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Court Restricts Protests In Lagos To Freedom, Peace Park

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Fans React to Jazz Jennings’ Inspiring Weight Loss Journey

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Technology
    Erie Canal’s 200th anniversary: How a technological marvel for trade changed the environment forever – The Conversation

    Erie Canal’s 200th Anniversary: How a Trade Marvel Transformed the Environment Forever

    Day 5 of Gains Streak for Solidion Technology Stock with 475% Return (vs. -20% YTD) [10/14/2025] – Trefis

    Solidion Technology Stock Rockets for 5th Consecutive Day, Soaring an Astonishing 475% Year-to-Date

    Tracking DNA and RNA Together To Unlock Disease Insights – Technology Networks

    Unlocking Disease Insights by Tracking DNA and RNA Together

    The future of battery technology – Engineer Live

    Revolutionizing Energy: Exploring the Future of Battery Technology

    How Can Boosting Your Travel Experience with Less Technology Lead to a More Relaxing Vacation? All You Need to Know About This Latest Trend – Travel And Tour World

    How Can Boosting Your Travel Experience with Less Technology Lead to a More Relaxing Vacation? All You Need to Know About This Latest Trend – Travel And Tour World

    Davenport CornCon Cybersecurity Conference helps students explore technology, AI use – KWQC

    Davenport CornCon Cybersecurity Conference Ignites Student Passion for Technology and AI Innovations

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s

August 6, 2023
in Health
Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s
Share on FacebookShare on Twitter

Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer's

Graphical abstract. Credit: iScience (2023). DOI: 10.1016/j.isci.2023.107522

The projected cost of caring for millions of individuals who have Alzheimer’s disease (AD) worldwide will exceed a $1 trillion in a few years. In addition to the enormous health burden, patients and their caregivers experience financial, physical and psychological strain. A theory regarding repeated drug failure in AD is that patients undergoing experimental therapies are selected too late in the disease process. Therefore, it is important to identify patients at a high risk of progression to AD in early stages of the disease.

To help identify persons who could benefit from early interventions, researchers from Boston University have developed a deep learning framework that can stratify individuals with mild cognitive impairment (MCI) based on their risk of advancing to AD.

“Quantifying the risk of progression to Alzheimer’s disease (AD) could help identify persons who could benefit from early interventions,” says corresponding author Vijaya B. Kolachalama, Ph.D., FAHA, associate professor of medicine at Boston University Chobanian & Avedisian School of Medicine.

The team studied data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and National Alzheimer’s Coordinating Center (NACC), separating individuals with mild cognitive impairment (MCI) into groups based on their brain fluid amyloid-β levels. They studied gray matter volume patterns within these groups to identify risk groups, validating their findings with expert assessments.

They developed models that combined neural networks with survival analysis to predict the progress from MCI to Alzheimer’s disease. They then linked their model predictions with biological evidence, confirming Alzheimer’s diagnoses with post-mortem data.

“By utilizing advances in interpretable machine learning, we demonstrated that brain regions relevant to AD such as the medial temporal lobe are among the most important regions for predicting progression risk, thereby assuring that our findings are consistent with established medical knowledge,” added Kolachalama.

According to the researchers, these findings represent innovation at the intersection of neurology and computer science, while underscoring model conformity with biological evidence using routinely collected information such as structural MRI to quantify risk of progression from MCI to AD.

“We utilized survival-based deep neural networks in conjunction with minimally processed structural MRI, a widely available, non-invasive technique. Further, by employing state-of-the-art deep learning methods in conjunction with SHapley Additive exPlanations (SHAP), a method based on cooperative game theory and used to increase transparency and interpretability of machine learning models, we were able to identify regions particularly important for predicting increased progression risk.”

These findings appear online in the journal iScience.

More information:
Michael F. Romano et al, Deep learning for risk-based stratification of cognitively impaired individuals, iScience (2023). DOI: 10.1016/j.isci.2023.107522

Citation:
Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s (2023, August 4)
retrieved 6 August 2023
from https://medicalxpress.com/news/2023-08-strategy-stratify-mild-cognitive-impairment.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2023-08-strategy-stratify-mild-cognitive-impairment.html

Tags: healthproposeResearchers
Previous Post

Valley fever could hit California hard. The drought-to-downpour cycle is to blame

Next Post

Consumer Health: Questions about breastfeeding

Using nature to help tackle mental health issues – Inside Ecology

Using nature to help tackle mental health issues – Inside Ecology

October 15, 2025
Get Inspired at the Bay Area Science Festival on Saturday, October 25 – marinmommies.com

Get Inspired at the Bay Area Science Festival on Saturday, October 25 – marinmommies.com

October 15, 2025
Scientists Found a Chemical That Could Help Regrow Your Hair. It Might Be In Your Pantry. – Popular Mechanics

This Common Pantry Ingredient Could Be the Key to Regrowing Your Hair

October 15, 2025
Face your fears in 4k: October State Theatre film lineup – The Daily Collegian

Conquer Your Fears in Stunning 4K: October Film Lineup at the State Theatre

October 15, 2025
Erie Canal’s 200th anniversary: How a technological marvel for trade changed the environment forever – The Conversation

Erie Canal’s 200th Anniversary: How a Trade Marvel Transformed the Environment Forever

October 15, 2025
Sporting KC to participate in 2026 Coachella Valley Invitational – Sporting Kansas City

Sporting KC Prepares for an Exciting Run at the 2026 Coachella Valley Invitational

October 15, 2025
Madagascar: Gen Z protesters united by an anime pirate flag are challenging governments around the world – NBC News

Madagascar: Gen Z protesters united by an anime pirate flag are challenging governments around the world – NBC News

October 15, 2025
New report reveals concerning blind spot posing risk to global economy: ‘Not a distant threat’ – Yahoo Finance

New report reveals concerning blind spot posing risk to global economy: ‘Not a distant threat’ – Yahoo Finance

October 15, 2025
Arts/Entertainment: ‘Wait Until Dark’ brings spooky season center stage – Times Herald Online

Wait Until Dark’ Delivers Chilling Thrills Perfect for the Spooky Season

October 15, 2025
Potential crisis looms with loss of environmental health research – Johns Hopkins University

Urgent Alert: Environmental Health Research at a Crossroads

October 15, 2025

Categories

Archives

October 2025
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (20,132)
  • Ecology (869)
  • Economy (890)
  • Entertainment (21,762)
  • General (17,615)
  • Health (9,932)
  • Lifestyle (903)
  • News (22,149)
  • People (891)
  • Politics (900)
  • Science (16,101)
  • Sports (21,390)
  • Technology (15,870)
  • World (873)

Recent News

Using nature to help tackle mental health issues – Inside Ecology

Using nature to help tackle mental health issues – Inside Ecology

October 15, 2025
Get Inspired at the Bay Area Science Festival on Saturday, October 25 – marinmommies.com

Get Inspired at the Bay Area Science Festival on Saturday, October 25 – marinmommies.com

October 15, 2025
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version