• About
  • Advertise
  • Privacy & Policy
  • Contact
Wednesday, October 4, 2023
Earth-News
  • Home
  • Business
  • Entertainment
    Man bags life imprisonment for sexually assaulting 4-year-old in church

    Man bags life imprisonment for sexually assaulting 4-year-old in church

    BBNaija All-Stars winner gets N120m cheque, Innoson’s victory ride + Videos, photos |

    BBNaija All-Stars winner gets N120m cheque, Innoson’s victory ride + Videos, photos |

    We spent N5.5billion in the production of BBNaija All Stars — Multichoice reveals – Lifestyle Nigeria

    We spent N5.5billion in the production of BBNaija All Stars — Multichoice reveals – Lifestyle Nigeria

    Fashola Sends Fresh Warning To Nigerians

    Fashola Sends Fresh Warning To Nigerians

    Ebunife And Ian’s Outdoor Wedding Was A Show Of Love, Beauty And Sweet Moments

    Ebunife And Ian’s Outdoor Wedding Was A Show Of Love, Beauty And Sweet Moments

    UCL: Osimhen fails to score as Real Madrid beat Napoli 3-2

    UCL: Osimhen fails to score as Real Madrid beat Napoli 3-2

  • General
  • Health
  • News
    InPics: Water lifting project adds vitality to county along Yellow River

    InPics: Water lifting project adds vitality to county along Yellow River

    Container throughput via land-sea trade corridor posts growth

    Container throughput via land-sea trade corridor posts growth

    InPics: The construction of key projects is advancing steadily in Xiong’an New Area

    InPics: The construction of key projects is advancing steadily in Xiong’an New Area

    China Focus: Chinese scientists establish meteorological observation stations on Mt. Cho Oyu

    China Focus: Chinese scientists establish meteorological observation stations on Mt. Cho Oyu

    Child care programs just lost thousands of federal dollars. Families and providers scramble to cope

    Child care programs just lost thousands of federal dollars. Families and providers scramble to cope

    Stock market today: Asian shares are sharply lower, tracking a rates-driven tumble on Wall Street

    Stock market today: Asian shares are sharply lower, tracking a rates-driven tumble on Wall Street

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Tech
    Rivian R1S Max pack battery with 400-mile range arrives on configurator as eye-watering US$16,000 option for dual-motor variants

    Rivian R1S Max pack battery with 400-mile range arrives on configurator as eye-watering US$16,000 option for dual-motor variants

    GameForce ACE and GameForce Indie arrive as new affordable gaming handhelds running LineageOS

    GameForce ACE and GameForce Indie arrive as new affordable gaming handhelds running LineageOS

    Acer Nitro 16 gaming laptop with Ryzen 9 7940HS and Nvidia RTX 4070 discounted down to US$1,349.99

    Acer Nitro 16 gaming laptop with Ryzen 9 7940HS and Nvidia RTX 4070 discounted down to US$1,349.99

    Cooler Master Tempest GP2711: Details of new 27-in gaming monitor with Mini LED backlight emerge

    Cooler Master Tempest GP2711: Details of new 27-in gaming monitor with Mini LED backlight emerge

    ASUS ROG Swift Pro PG248QP: Full technical specifications finally revealed for long-awaited 540 Hz gaming monitor

    ASUS ROG Swift Pro PG248QP: Full technical specifications finally revealed for long-awaited 540 Hz gaming monitor

    Google announces Chromebook Plus program to designate Chromebooks with higher-end specs, AI features, and more

    Google announces Chromebook Plus program to designate Chromebooks with higher-end specs, AI features, and more

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
  • Home
  • Business
  • Entertainment
    Man bags life imprisonment for sexually assaulting 4-year-old in church

    Man bags life imprisonment for sexually assaulting 4-year-old in church

    BBNaija All-Stars winner gets N120m cheque, Innoson’s victory ride + Videos, photos |

    BBNaija All-Stars winner gets N120m cheque, Innoson’s victory ride + Videos, photos |

    We spent N5.5billion in the production of BBNaija All Stars — Multichoice reveals – Lifestyle Nigeria

    We spent N5.5billion in the production of BBNaija All Stars — Multichoice reveals – Lifestyle Nigeria

    Fashola Sends Fresh Warning To Nigerians

    Fashola Sends Fresh Warning To Nigerians

    Ebunife And Ian’s Outdoor Wedding Was A Show Of Love, Beauty And Sweet Moments

    Ebunife And Ian’s Outdoor Wedding Was A Show Of Love, Beauty And Sweet Moments

    UCL: Osimhen fails to score as Real Madrid beat Napoli 3-2

    UCL: Osimhen fails to score as Real Madrid beat Napoli 3-2

  • General
  • Health
  • News
    InPics: Water lifting project adds vitality to county along Yellow River

    InPics: Water lifting project adds vitality to county along Yellow River

    Container throughput via land-sea trade corridor posts growth

    Container throughput via land-sea trade corridor posts growth

    InPics: The construction of key projects is advancing steadily in Xiong’an New Area

    InPics: The construction of key projects is advancing steadily in Xiong’an New Area

    China Focus: Chinese scientists establish meteorological observation stations on Mt. Cho Oyu

    China Focus: Chinese scientists establish meteorological observation stations on Mt. Cho Oyu

    Child care programs just lost thousands of federal dollars. Families and providers scramble to cope

    Child care programs just lost thousands of federal dollars. Families and providers scramble to cope

    Stock market today: Asian shares are sharply lower, tracking a rates-driven tumble on Wall Street

    Stock market today: Asian shares are sharply lower, tracking a rates-driven tumble on Wall Street

    Trending Tags

    • Trump Inauguration
    • United Stated
    • White House
    • Market Stories
    • Election Results
  • Science
  • Sports
  • Tech
    Rivian R1S Max pack battery with 400-mile range arrives on configurator as eye-watering US$16,000 option for dual-motor variants

    Rivian R1S Max pack battery with 400-mile range arrives on configurator as eye-watering US$16,000 option for dual-motor variants

    GameForce ACE and GameForce Indie arrive as new affordable gaming handhelds running LineageOS

    GameForce ACE and GameForce Indie arrive as new affordable gaming handhelds running LineageOS

    Acer Nitro 16 gaming laptop with Ryzen 9 7940HS and Nvidia RTX 4070 discounted down to US$1,349.99

    Acer Nitro 16 gaming laptop with Ryzen 9 7940HS and Nvidia RTX 4070 discounted down to US$1,349.99

    Cooler Master Tempest GP2711: Details of new 27-in gaming monitor with Mini LED backlight emerge

    Cooler Master Tempest GP2711: Details of new 27-in gaming monitor with Mini LED backlight emerge

    ASUS ROG Swift Pro PG248QP: Full technical specifications finally revealed for long-awaited 540 Hz gaming monitor

    ASUS ROG Swift Pro PG248QP: Full technical specifications finally revealed for long-awaited 540 Hz gaming monitor

    Google announces Chromebook Plus program to designate Chromebooks with higher-end specs, AI features, and more

    Google announces Chromebook Plus program to designate Chromebooks with higher-end specs, AI features, and more

    Trending Tags

    • Nintendo Switch
    • CES 2017
    • Playstation 4 Pro
    • Mark Zuckerberg
No Result
View All Result
Earth-News
No Result
View All Result
Home Health

Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s

August 6, 2023
in Health
Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s
Share on FacebookShare on Twitter

Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer's

Graphical abstract. Credit: iScience (2023). DOI: 10.1016/j.isci.2023.107522

The projected cost of caring for millions of individuals who have Alzheimer’s disease (AD) worldwide will exceed a $1 trillion in a few years. In addition to the enormous health burden, patients and their caregivers experience financial, physical and psychological strain. A theory regarding repeated drug failure in AD is that patients undergoing experimental therapies are selected too late in the disease process. Therefore, it is important to identify patients at a high risk of progression to AD in early stages of the disease.

To help identify persons who could benefit from early interventions, researchers from Boston University have developed a deep learning framework that can stratify individuals with mild cognitive impairment (MCI) based on their risk of advancing to AD.

“Quantifying the risk of progression to Alzheimer’s disease (AD) could help identify persons who could benefit from early interventions,” says corresponding author Vijaya B. Kolachalama, Ph.D., FAHA, associate professor of medicine at Boston University Chobanian & Avedisian School of Medicine.

The team studied data from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) and National Alzheimer’s Coordinating Center (NACC), separating individuals with mild cognitive impairment (MCI) into groups based on their brain fluid amyloid-β levels. They studied gray matter volume patterns within these groups to identify risk groups, validating their findings with expert assessments.

They developed models that combined neural networks with survival analysis to predict the progress from MCI to Alzheimer’s disease. They then linked their model predictions with biological evidence, confirming Alzheimer’s diagnoses with post-mortem data.

“By utilizing advances in interpretable machine learning, we demonstrated that brain regions relevant to AD such as the medial temporal lobe are among the most important regions for predicting progression risk, thereby assuring that our findings are consistent with established medical knowledge,” added Kolachalama.

According to the researchers, these findings represent innovation at the intersection of neurology and computer science, while underscoring model conformity with biological evidence using routinely collected information such as structural MRI to quantify risk of progression from MCI to AD.

“We utilized survival-based deep neural networks in conjunction with minimally processed structural MRI, a widely available, non-invasive technique. Further, by employing state-of-the-art deep learning methods in conjunction with SHapley Additive exPlanations (SHAP), a method based on cooperative game theory and used to increase transparency and interpretability of machine learning models, we were able to identify regions particularly important for predicting increased progression risk.”

These findings appear online in the journal iScience.

More information:
Michael F. Romano et al, Deep learning for risk-based stratification of cognitively impaired individuals, iScience (2023). DOI: 10.1016/j.isci.2023.107522

Citation:
Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s (2023, August 4)
retrieved 6 August 2023
from https://medicalxpress.com/news/2023-08-strategy-stratify-mild-cognitive-impairment.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Medical Xpress – https://medicalxpress.com/news/2023-08-strategy-stratify-mild-cognitive-impairment.html

Tags: healthproposeResearchers
Previous Post

Valley fever could hit California hard. The drought-to-downpour cycle is to blame

Next Post

Consumer Health: Questions about breastfeeding

InPics: Water lifting project adds vitality to county along Yellow River

InPics: Water lifting project adds vitality to county along Yellow River

October 4, 2023
Container throughput via land-sea trade corridor posts growth

Container throughput via land-sea trade corridor posts growth

October 4, 2023
InPics: The construction of key projects is advancing steadily in Xiong’an New Area

InPics: The construction of key projects is advancing steadily in Xiong’an New Area

October 4, 2023
China Focus: Chinese scientists establish meteorological observation stations on Mt. Cho Oyu

China Focus: Chinese scientists establish meteorological observation stations on Mt. Cho Oyu

October 4, 2023
Child care programs just lost thousands of federal dollars. Families and providers scramble to cope

Child care programs just lost thousands of federal dollars. Families and providers scramble to cope

October 4, 2023
Stock market today: Asian shares are sharply lower, tracking a rates-driven tumble on Wall Street

Stock market today: Asian shares are sharply lower, tracking a rates-driven tumble on Wall Street

October 4, 2023
A test case of another kind for the Supreme Court: Who can sue hotels over disability access

A test case of another kind for the Supreme Court: Who can sue hotels over disability access

October 4, 2023
Lahaina residents deliver petition asking Hawaii governor to delay tourism reopening

Lahaina residents deliver petition asking Hawaii governor to delay tourism reopening

October 4, 2023
The CEO of IBM says he doesn’t intend to ‘get rid of’ a single programmer because of AI

The CEO of IBM says he doesn’t intend to ‘get rid of’ a single programmer because of AI

October 4, 2023
The gag order in Trump’s civil fraud case not surprising, legal expert says, but he’s not likely to face a fine or jail time if he breaks it

The gag order in Trump’s civil fraud case not surprising, legal expert says, but he’s not likely to face a fine or jail time if he breaks it

October 4, 2023
Partenaires
afric.info
europ.info
usa-news
lesmeilleureschaussures.fr
goodsforyoutoday.com
looktopbeauty.com
keto-diet.biz
soccernews.info
nba-news.net
sportsprblog.com compar.biz
the-best.top
bestchoices.biz
expert-plus.fr
travel-mag.info
pksportsnews.com
news-sports.org

Categories

Archives

October 2023
M T W T F S S
 1
2345678
9101112131415
16171819202122
23242526272829
3031  
« Sep    
Earth-News.info

The Earth News is an independent English-language daily published Website from all around the World News

Browse by Category

  • Business (3,857)
  • Entertainment (3,959)
  • General (2,927)
  • Health (1,881)
  • News (4,464)
  • Science (3,037)
  • Sports (4,111)
  • Tech (2,995)

Recent News

InPics: Water lifting project adds vitality to county along Yellow River

InPics: Water lifting project adds vitality to county along Yellow River

October 4, 2023
Container throughput via land-sea trade corridor posts growth

Container throughput via land-sea trade corridor posts growth

October 4, 2023
  • About
  • Advertise
  • Privacy & Policy
  • Contact

© 2023 earth-news.info

No Result
View All Result

© 2023 earth-news.info

Go to mobile version

Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s- https://www.maquillages.info/   https://maquillages.org   https://www.deguisements-fetes.fr   https://maillots-de-bain-shop.com   https://www.le-noeud-papillon.com   https://www.jeepeg.fr   https://maillotde-bain.com   https://pushkarvisit.com   -/- According to Luke Fickell, Wisconsin is ‘all-in’ on NIL   Barbie film hits $1bn mark at global box office   Zhuhai Championships: Andy Murray loses to Aslan Karatsev in last 16   Breece Hall named Jets’ offensive X-factor for 2023   Soundking AK20 BA Amplificateur pour Basse   -*-$$DAKINE Split Roller Mallette ordinateur à roulettes, 21 cm, 110 L, Carbon   Veuve Clicquot – Coffret Retraite V.Clicquot Rose   Enceinte Mobile 700W Sono Active DJ KARAOKE 12″ Autonome Batterie à LED RVB + Micro VHF USB/SD/Bluetooth – LedWood Boostar1400   Volkswagen: IT-Störung bei Volkswagen behoben   Newcastle adds BetMGM UK to its bookmaker alliances   $$* Amalia   El Rancho Place d’Italie, Centre commercial Italie 2, place d’Italie 75013 Paris   Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s *Researchers propose a strategy to stratify risk of progression from mild cognitive impairment to Alzheimer’s