An engineered retrotransposon achieves targeted gene transfer into the human genome.
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Fig. 1: Comparison of transposon systems used for transgene integration.
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Authors and Affiliations
Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
Fred Dyda & Alison B. Hickman
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Dyda, F., Hickman, A.B. A retrotransposon for site-specific gene transfer.
Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02180-9
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Published: 18 March 2024
DOI: https://doi.org/10.1038/s41587-024-02180-9
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