News & Views
Published: 17 May 2024
Genomics
Nature Biotechnology
(2024)Cite this article
Two CRISPR tools for combinatorial genetic perturbations reveal gene regulatory networks.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
24,99 € / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
209,00 € per year
only 17,42 € per issue
Buy this article
Purchase on Springer LinkInstant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Additional access options:
Log in
Learn about institutional subscriptions
Read our FAQs
Contact customer support
Fig. 1: Two novel CRISPR tools to map genomic regulatory sequences.
References
Pacalin, N. M. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-024-02213-3 (2024).
Article
Google Scholar
Hsiung, C. C.-S. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-024-02224-0 (2024).
Article
Google Scholar
Henikoff, S. & Ahmad, K. Protein Sci.31, e4458 (2022).
Article
CAS
PubMed
PubMed Central
Google Scholar
Melnikov, A. et al. Nat. Biotechnol.30, 271–277 (2012).
Article
CAS
PubMed
PubMed Central
Google Scholar
Arnold, C. D. et al. Science339, 1074–1077 (2013).
Article
CAS
PubMed
Google Scholar
Fulco, C. P. et al. Nat. Genet.51, 1664–1669 (2019).
Article
CAS
PubMed
PubMed Central
Google Scholar
Najm, F. J. et al. Nat. Biotechnol.36, 179–189 (2018).
Article
CAS
PubMed
Google Scholar
Boettcher, M. et al. Nat. Biotechnol.36, 170–178 (2018).
Article
CAS
PubMed
PubMed Central
Google Scholar
Gasperini, M. et al. Cell176, 377–390.e19 (2019).
Article
CAS
PubMed
PubMed Central
Google Scholar
Download references
Author information
Authors and Affiliations
Department of Microbiology and Immunology & UCSF Diabetes Center, University of California, San Francisco, San Francisco, CA, USA
Stefan Oberlin & Michael T. McManus
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
About this article
Cite this article
Oberlin, S., McManus, M.T. Decoding gene regulation with CRISPR perturbations.
Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02222-2
Download citation
Published: 17 May 2024
DOI: https://doi.org/10.1038/s41587-024-02222-2
>>> Read full article>>>
Copyright for syndicated content belongs to the linked Source : Nature.com – https://www.nature.com/articles/s41587-024-02222-2
